1KNK
Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli involved in Mevalonate-Independent Isoprenoid Biosynthesis
Summary for 1KNK
Entry DOI | 10.2210/pdb1knk/pdb |
Related | 1KNJ |
Descriptor | 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MANGANESE (II) ION (3 entities in total) |
Functional Keywords | isoprenoids, deoxyxylulose/methyl-erythritol-phosphate pathway, cyclodiphosphate, mep, ygbb, ispf, mecdp, 2-c-methyl-d-erythritol-2, 4-cyclodiphosphate synthase, metal binding protein |
Biological source | Escherichia coli |
Total number of polymer chains | 1 |
Total formula weight | 16975.47 |
Authors | Richard, S.B.,Ferrer, J.L.,Bowman, M.E.,Lillo, A.M.,Tetzlaff, C.N.,Cane, D.E.,Noel, J.P. (deposition date: 2001-12-18, release date: 2002-06-18, Last modification date: 2023-08-16) |
Primary citation | Richard, S.B.,Ferrer, J.L.,Bowman, M.E.,Lillo, A.M.,Tetzlaff, C.N.,Cane, D.E.,Noel, J.P. Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway. J.Biol.Chem., 277:8667-8672, 2002 Cited by PubMed: 11786530DOI: 10.1074/jbc.C100739200 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.8 Å) |
Structure validation
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