7OCH
 
 | | Apo-structure of Lassa virus L protein (well-resolved polymerase core) [APO-CORE] | | 分子名称: | MAGNESIUM ION, RNA-directed RNA polymerase L, ZINC ION | | 著者 | Kouba, T, Vogel, D, Thorkelsson, S, Quemin, E, Williams, H.M, Milewski, M, Busch, C, Gunther, S, Grunewald, K, Rosenthal, M, Cusack, S. | | 登録日 | 2021-04-26 | | 公開日 | 2021-12-01 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | | 主引用文献 | Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.
Nat Commun, 12, 2021
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7MKT
 | | Crystal structure of r(GU)11G-NMM complex | | 分子名称: | N-METHYLMESOPORPHYRIN, POTASSIUM ION, RNA (5'-R(*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*GP*UP*G)-3') | | 著者 | Bingman, C.A, Roschdi, S, Nomura, Y, Butcher, S.E. | | 登録日 | 2021-04-26 | | 公開日 | 2022-11-02 | | 最終更新日 | 2024-05-22 | | 実験手法 | X-RAY DIFFRACTION (1.97 Å) | | 主引用文献 | An atypical RNA quadruplex marks RNAs as vectors for gene silencing.
Nat.Struct.Mol.Biol., 29, 2022
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7MKA
 | | Structure of EC+EC (leading EC-focused) | | 分子名称: | DNA (40-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | 著者 | Yang, C, Murakami, K. | | 登録日 | 2021-04-22 | | 公開日 | 2022-04-27 | | 最終更新日 | 2023-05-17 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
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7MK9
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7OA4
 | | Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001 | | 分子名称: | (2Z)-4-[1-benzyl-4-(4-chlorobenzyl)piperidin-4-yl]-2-hydroxy-4-oxobut-2-enoic acid, FORMIC ACID, MANGANESE (II) ION, ... | | 著者 | Feracci, M, Hernandez, S, Vincentelli, R, Ferron, F, Reguera, J, Canard, B, Alvarez, K. | | 登録日 | 2021-04-19 | | 公開日 | 2022-08-03 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structure of the N-terminal endonuclease domain of La Crosse virus L-protein bound to compound L-742,001
To Be Published
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7O7Z
 | | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (classified for pseudoknot) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | | 登録日 | 2021-04-14 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
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7O80
 | | Rabbit 80S ribosome in complex with eRF1 and ABCE1 stalled at the STOP codon in the mutated SARS-CoV-2 slippery site | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | | 登録日 | 2021-04-14 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
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7O81
 | | Rabbit 80S ribosome colliding in another ribosome stalled by the SARS-CoV-2 pseudoknot | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | | 登録日 | 2021-04-14 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
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7O7Y
 | | Rabbit 80S ribosome stalled close to the mutated SARS-CoV-2 slippery site by a pseudoknot (high resolution) | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Bhatt, P.R, Scaiola, A, Leibundgut, M.A, Atkins, J.F, Ban, N. | | 登録日 | 2021-04-14 | | 公開日 | 2021-06-02 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | | 主引用文献 | Structural basis of ribosomal frameshifting during translation of the SARS-CoV-2 RNA genome.
Science, 372, 2021
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7O75
 | | Yeast RNA polymerase II transcription pre-initiation complex with open promoter DNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | 登録日 | 2021-04-13 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7ELL
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7O73
 | | Yeast RNA polymerase II transcription pre-initiation complex with closed distorted promoter DNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | 登録日 | 2021-04-12 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7O72
 | | Yeast RNA polymerase II transcription pre-initiation complex with closed promoter DNA | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | 登録日 | 2021-04-12 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7ELH
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7ELC
 | | Structure of monomeric complex of MACV L bound to Z and 3'-vRNA | | 分子名称: | 3'-vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | | 著者 | Xu, X, Peng, R, Peng, Q, Shi, Y. | | 登録日 | 2021-04-09 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
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7ELA
 | | Structure of Lassa virus polymerase in complex with 3'-vRNA and Z mutant (F36A) | | 分子名称: | 3-'vRNA promoter, MANGANESE (II) ION, RING finger protein Z, ... | | 著者 | Xu, X, Peng, R, Peng, Q, Shi, Y. | | 登録日 | 2021-04-09 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
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7EL9
 | | Structure of Machupo virus L polymerase in complex with Z protein and 3'-vRNA (dimeric complex) | | 分子名称: | MANGANESE (II) ION, Machupo virus 3'-vRNA promoter, RING finger protein Z, ... | | 著者 | Peng, R, Xu, X, Peng, Q, Shi, Y. | | 登録日 | 2021-04-09 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
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7ELB
 | | Structure of Machupo virus L polymerase in complex with Z protein (dimeric form) | | 分子名称: | MANGANESE (II) ION, RING finger protein Z, RNA-directed RNA polymerase L, ... | | 著者 | Peng, R, Xu, X, Peng, Q, Shi, Y. | | 登録日 | 2021-04-09 | | 公開日 | 2021-05-05 | | 最終更新日 | 2021-07-14 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Cryo-EM structures of Lassa and Machupo virus polymerases complexed with cognate regulatory Z proteins identify targets for antivirals.
Nat Microbiol, 6, 2021
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7MEI
 | | Composite structure of EC+EC | | 分子名称: | DNA (74-MER), DNA-directed RNA polymerase II subunit RPB11, DNA-directed RNA polymerase II subunit RPB3, ... | | 著者 | Yang, C, Murakami, K. | | 登録日 | 2021-04-06 | | 公開日 | 2022-03-02 | | 実験手法 | ELECTRON MICROSCOPY (3.54 Å) | | 主引用文献 | Structural visualization of de novo transcription initiation by Saccharomyces cerevisiae RNA polymerase II.
Mol.Cell, 82, 2022
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7O4J
 | | Yeast RNA polymerase II transcription pre-initiation complex (consensus) | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | 登録日 | 2021-04-06 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7O4I
 | | Yeast RNA polymerase II transcription pre-initiation complex with initial transcription bubble | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | 登録日 | 2021-04-06 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7O4L
 | | Yeast TFIIH in the expanded state within the pre-initiation complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | 登録日 | 2021-04-06 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7O4K
 | | Yeast TFIIH in the contracted state within the pre-initiation complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, BERYLLIUM TRIFLUORIDE ION, DNA-directed RNA polymerase II subunit RPB1, ... | | 著者 | Schilbach, S, Aibara, S, Dienemann, C, Grabbe, F, Cramer, P. | | 登録日 | 2021-04-06 | | 公開日 | 2021-06-16 | | 最終更新日 | 2021-08-04 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | Structure of RNA polymerase II pre-initiation complex at 2.9 angstrom defines initial DNA opening.
Cell, 184, 2021
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7EKJ
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7EJU
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