7OE3

Apo-structure of Lassa virus L protein (well-resolved endonuclease) [APO-ENDO]

Summary for 7OE3

• Entry DOI: 10.2210/pdb7oe3/pdb
• Related: 7OCH
• EMDB information: 12860
• Descriptor: RNA-directed RNA polymerase L, ZINC ION, MAGNESIUM ION (3 entities in total)
• Functional Keywords: lassa virus rna-dependent rna polymerase viral rna, viral protein
• Biological source: Lassa mammarenavirus
• Total number of polymer chains: 1
• Total formula weight: 253746.65

Authors

Kouba, T.,Vogel, D.,Thorkelsson, S.,Quemin, E.,Williams, H.M.,Milewski, M.,Busch, C.,Gunther, S.,Grunewald, K.,Rosenthal, M.,Cusack, S. (deposition date: 2021-05-01, release date: 2021-12-01, Last modification date: 2024-05-01)

• Primary citation: Kouba, T.,Vogel, D.,Thorkelsson, S.R.,Quemin, E.R.J.,Williams, H.M.,Milewski, M.,Busch, C.,Gunther, S.,Grunewald, K.,Rosenthal, M.,Cusack, S.; Conformational changes in Lassa virus L protein associated with promoter binding and RNA synthesis activity.; Nat Commun, 12:7018-7018, 2021; PubMed: 34857749; DOI: 10.1038/s41467-021-27305-5

Experimental method

ELECTRON MICROSCOPY (3.35 Å)