PDB: 674 件ウェブページステータス検索Chemie searchBIRD

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1EDB	CRYSTALLOGRAPHIC AND FLUORESCENCE STUDIES OF THE INTERACTION OF HALOALKANE DEHALOGENASE WITH HALIDE IONS: STUDIES WITH HALIDE COMPOUNDS REVEAL A HALIDE BINDING SITE IN THE ACTIVE SITE 分子名称: CHLORIDE ION, HALOALKANE DEHALOGENASE 著者 Verschueren, K.H.G, Dijkstra, B.W. 登録日 1993-05-13 公開日 1993-10-31 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions. Studies with halide compounds reveal a halide binding site in the active site. Biochemistry, 32, 1993
5Y2X	Crystal structure of apo-HaloTag (M175C) 分子名称: CHLORIDE ION, Haloalkane dehalogenase 著者 Lee, H, Kang, M, Rhee, H, Lee, C. 登録日 2017-07-27 公開日 2017-09-06 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Structure-guided synthesis of a protein-based fluorescent sensor for alkyl halides Chem. Commun. (Camb.), 53, 2017
4UFO	Laboratory evolved variant R-C1B1D33E6 of potato epoxide hydrolase StEH1 分子名称: EPOXIDE HYDROLASE 著者 Carlsson, A.J, Bauer, P, Nilsson, M, Dobritzsch, D, Kamerlin, S.C.L, Widersten, M. 登録日 2015-03-17 公開日 2016-04-13 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Laboratory Evolved Enzymes Provide Snapshots of the Development of Enantioconvergence in Enzyme-Catalyzed Epoxide Hydrolysis. Chembiochem, 17, 2016
3T4U	L29I Mutation in an Aryl Esterase from Pseudomonas fluorescens Leads to Unique Peptide Flip and Increased Activity 分子名称: Arylesterase, CHLORIDE ION, GLYCEROL, ... 著者 Kazlauskas, R.J, Yin, T, Purpero, V.M. 登録日 2011-07-26 公開日 2012-08-01 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 L29I Mutation in an Aryl Esterase from Pseudomonas fluorescens Leads to Unique Peptide Flip and Increased Activity To be Published
6COI	AtHNL enantioselectivity mutant At-A9-H7 Apo, Y13C,Y121L,P126F,L128W,C131T,A209I with CYANIDE, benzaldehyde, MANDELIC ACID NITRILE 分子名称: (2R)-hydroxy(phenyl)ethanenitrile, (S)-MANDELIC ACID NITRILE, Alpha-hydroxynitrile lyase, ... 著者 Jones, B.J, Kazlauskas, R.J, Desrouleaux, R. 登録日 2018-03-12 公開日 2019-03-20 最終更新日 2023-10-04 実験手法 X-RAY DIFFRACTION (2.024 Å) 主引用文献 AtHNL enantioselectivity mutants To be published
7C4D	Marine microorganism esterase 分子名称: 1,2-ETHANEDIOL, ACETATE ION, Putative esterase, ... 著者 Zhu, C.H, Wu, Y.K, Isupov, M.N. 登録日 2020-05-16 公開日 2021-05-26 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Structural Insights into a Novel Esterase from the East Pacific Rise and Its Improved Thermostability by a Semirational Design. J.Agric.Food Chem., 69, 2021
8E19	Crystal structure of TnmK1 complexed with TNM H 分子名称: (1R,8S,13S)-8-[(4-hydroxy-9,10-dioxo-9,10-dihydroanthracen-1-yl)amino]-12-methoxy-10-methylbicyclo[7.3.1]trideca-9,11-diene-2,6-diyne-13-carbaldehyde, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, SUCCINIC ACID, ... 著者 Liu, Y.-C, Gui, C, Shen, B. 登録日 2022-08-10 公開日 2022-11-09 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Intramolecular C-C Bond Formation Links Anthraquinone and Enediyne Scaffolds in Tiancimycin Biosynthesis. J.Am.Chem.Soc., 144, 2022
5AKJ	ligand complex structure of soluble epoxide hydrolase 分子名称: 2-(1H-BENZIMIDAZOL-2-YLSULFANYL)ETHANOL, BIFUNCTIONAL EPOXIDE HYDROLASE 2, DIMETHYL SULFOXIDE, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-03 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
4Y2P	Structure of soluble epoxide hydrolase in complex with N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine 分子名称: Bifunctional epoxide hydrolase 2, MAGNESIUM ION, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine 著者 Amano, Y, Yamaguchi, T. 登録日 2015-02-10 公開日 2015-05-06 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Identification of N-ethylmethylamine as a novel scaffold for inhibitors of soluble epoxide hydrolase by crystallographic fragment screening Bioorg.Med.Chem., 23, 2015
4ETW	Structure of the Enzyme-ACP Substrate Gatekeeper Complex Required for Biotin Synthesis 分子名称: Acyl carrier protein, Pimelyl-[acyl-carrier protein] methyl ester esterase, methyl 7-{[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl]sulfanyl}-7-oxoheptanoate 著者 Agarwal, V, Nair, S.K. 登録日 2012-04-24 公開日 2012-10-17 最終更新日 2019-07-17 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Structure of the enzyme-acyl carrier protein (ACP) substrate gatekeeper complex required for biotin synthesis. Proc.Natl.Acad.Sci.USA, 109, 2012
1BRO	BROMOPEROXIDASE A2 分子名称: BROMOPEROXIDASE A2 著者 Hecht, H.J, Sobek, H, Haag, T, Pfeifer, O, Van Pee, K.H. 登録日 1996-06-01 公開日 1996-12-07 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 The metal-ion-free oxidoreductase from Streptomyces aureofaciens has an alpha/beta hydrolase fold. Nat.Struct.Biol., 1, 1994
4C4Z	Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with A8 分子名称: 1-ethyl-3-naphthalen-1-ylurea, BIFUNCTIONAL EPOXIDE HYDROLASE 2 著者 Pilger, J, Mazur, A, Monecke, P, Schreuder, H, Elshorst, B, Langer, T, Schiffer, A, Krimm, I, Wegstroth, M, Lee, D, Hessler, G, Wendt, K.-U, Becker, S, Griesinger, C. 登録日 2013-09-09 公開日 2014-10-01 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 A Combination of Spin Diffusion Methods for the Determination of Protein-Ligand Complex Structural Ensembles. Angew.Chem.Int.Ed.Engl., 54, 2015
5ALP	ligand complex structure of soluble epoxide hydrolase 分子名称: BIFUNCTIONAL EPOXIDE HYDROLASE 2, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-08 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.06 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
2PU7	Crystal Structure of S112A/H265A double mutant of a C-C hydrolase, BphD, from Burkholderia xenovorans LB400 分子名称: 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase, MALONATE ION, SODIUM ION 著者 Bhowmik, S, Bolin, J.T. 登録日 2007-05-08 公開日 2007-05-22 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.07 Å) 主引用文献 The Tautomeric Half-reaction of BphD, a C-C Bond Hydrolase: KINETIC AND STRUCTURAL EVIDENCE SUPPORTING A KEY ROLE FOR HISTIDINE 265 OF THE CATALYTIC TRIAD. J.Biol.Chem., 282, 2007
6JR5	ZHD/H242A complex with bZOL 分子名称: (3S,7S,11E)-7,14,16-trihydroxy-3-methyl-3,4,5,6,7,8,9,10-octahydro-1H-2-benzoxacyclotetradecin-1-one, GLYCEROL, Zearalenone hydrolase 著者 Hu, X.J. 登録日 2019-04-02 公開日 2020-04-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.08 Å) 主引用文献 Structure of ZHD complex To Be Published
6JQZ	ZHD/H242A complex with ZEN 分子名称: (3S,11E)-14,16-dihydroxy-3-methyl-3,4,5,6,9,10-hexahydro-1H-2-benzoxacyclotetradecine-1,7(8H)-dione, GLYCEROL, Zearalenone hydrolase 著者 Hu, X.J. 登録日 2019-04-02 公開日 2020-04-08 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structure of ZHD complex To Be Published
5AKX	ligand complex structure of soluble epoxide hydrolase 分子名称: 5-iodanyl-1H-indazole, DIMETHYL SULFOXIDE, SOLUBLE EPOXIDE HYDROLASE, ... 著者 Oster, L, Tapani, S, Xue, Y, Kack, H. 登録日 2015-03-05 公開日 2015-05-13 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Successful Generation of Structural Information for Fragment-Based Drug Discovery. Drug Discov Today, 20, 2015
2WJ3	CRYSTAL STRUCTURE OF THE COFACTOR-DEVOID 1-H-3-HYDROXY-4- OXOQUINALDINE 2,4-DIOXYGENASE (HOD) FROM ARTHROBACTER NITROGUAJACOLICUS RU61A 分子名称: 1-H-3-HYDROXY-4-OXOQUINALDINE 2,4-DIOXYGENASE, GLYCEROL, S,R MESO-TARTARIC ACID 著者 Steiner, R.A. 登録日 2009-05-20 公開日 2010-01-26 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Structural Basis for Cofactor-Independent Dioxygenation of N-Heteroaromatic Compounds at the {Alpha}/{Beta}-Hydrolase Fold. Proc.Natl.Acad.Sci.USA, 107, 2010
7COG	Cholesterol esterase from Burkholderia stabilis (monoclinic crystal form) 分子名称: Alpha/beta hydrolase, CALCIUM ION 著者 Yasutake, Y, Tamura, T. 登録日 2020-08-04 公開日 2020-12-16 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.098 Å) 主引用文献 Bacterial triacylglycerol lipase is a potential cholesterol esterase: Identification of a key determinant for sterol-binding specificity. Int.J.Biol.Macromol., 167, 2021
7OO4	HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridine Dye 分子名称: 4-[(E)-2-[1-(7-chloranylheptyl)pyridin-1-ium-4-yl]ethenyl]-N,N-dimethyl-aniline, CHLORIDE ION, Haloalkane dehalogenase 著者 Stein, A, Liang, A.D. 登録日 2021-05-26 公開日 2021-07-21 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 HaloTag Engineering for Enhanced Fluorogenicity and Kinetics with a Styrylpyridium Dye. Chembiochem, 22, 2021
1WM1	Crystal Structure of Prolyl Aminopeptidase, Complex with Pro-TBODA 分子名称: (5-TERT-BUTYL-1,3,4-OXADIAZOL-2-YL)[(2R)-PYRROLIDIN-2-YL]METHANONE, Proline iminopeptidase 著者 Nakajima, Y, Inoue, T, Ito, K, Tozaka, T, Hatakeyama, S, Tanaka, N, Nakamura, K.T, Yoshimoto, T. 登録日 2004-07-01 公開日 2004-07-20 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Novel inhibitor for prolyl aminopeptidase from Serratia marcescens and studies on the mechanism of substrate recognition of the enzyme using the inhibitor ARCH.BIOCHEM.BIOPHYS., 416, 2003
2LIP	PSEUDOMONAS LIPASE OPEN CONFORMATION 分子名称: CALCIUM ION, LIPASE 著者 Schrag, J.D, Cygler, M. 登録日 1996-12-13 公開日 1997-03-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The open conformation of a Pseudomonas lipase. Structure, 5, 1997
1XQX	Crystal structure of F1-mutant S105A complex with PCK 分子名称: PHENYLALANYLMETHYLCHLORIDE, Proline iminopeptidase 著者 Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. 登録日 2004-10-13 公開日 2005-07-12 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
7AL6	Crystal structure of the hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Probable hydrolase, ... 著者 Feiler, C.G, Blankenfeldt, W. 登録日 2020-10-05 公開日 2020-10-14 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of the hypothetical protein PA1622 from Pseudomonas aeruginosa PAO1 To Be Published
1U2E	Crystal Structure of the C-C bond hydrolase MhpC 分子名称: 2-hydroxy-6-ketonona-2,4-dienedioic acid hydrolase, CHLORIDE ION 著者 Montgomery, M.G, Dunn, G, Mohammed, F, Robertson, T, Garcia, J.-L, Coker, A, Bugg, T.D.H, Wood, S.P. 登録日 2004-07-19 公開日 2005-02-15 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The Structure of the C-C Bond Hydrolase MhpC Provides Insights into its Catalytic Mechanism J.Mol.Biol., 346, 2005

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