4Y2P

Structure of soluble epoxide hydrolase in complex with N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine

Summary for 4Y2P

Entry DOI	10.2210/pdb4y2p/pdb
Related	4Y2J 4Y2Q 4Y2R 4Y2S 4Y2T 4Y2U 4Y2V 4Y2X 4Y2Y
Descriptor	Bifunctional epoxide hydrolase 2, MAGNESIUM ION, N-methyl-1-[3-(pyridin-3-yl)phenyl]methanamine, ... (4 entities in total)
Functional Keywords	inhibitor complex, hydrolase, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
Biological source	Homo sapiens (Human)
Total number of polymer chains	1
Total formula weight	63737.08
Authors	Amano, Y.,Yamaguchi, T. (deposition date: 2015-02-10, release date: 2015-05-06, Last modification date: 2024-03-20)
Primary citation	Amano, Y.,Tanabe, E.,Yamaguchi, T. Identification of N-ethylmethylamine as a novel scaffold for inhibitors of soluble epoxide hydrolase by crystallographic fragment screening Bioorg.Med.Chem., 23:2310-2317, 2015 Cited by PubMed: 25862210 DOI: 10.1016/j.bmc.2015.03.083 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation