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6L49
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BU of 6l49 by Molmil
H3-CA-H3 tri-nucleosome with the 22 base-pair linker DNA
分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H.
登録日2019-10-16
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (18.9 Å)
主引用文献Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
Structure, 28, 2020
5FM3
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BU of 5fm3 by Molmil
Crystal structure of hyper-phosphorylated RET kinase domain with (proximal) juxtamembrane segment
分子名称: 1-TER-BUTYL-3-P-TOLYL-1H-PYRAZOLO[3,4-D]PYRIMIDIN-4-YLAMINE, PROTO-ONCOGENE TYROSINE-PROTEIN KINASE RECEPTOR RET
著者Plaza-Menacho, I, Barnouin, K, Barry, R, Borg, A, Orme, M, Mouilleron, S, Martinez-Torres, R.J, Meier, P, McDonald, N.Q.
登録日2015-10-30
公開日2016-12-28
最終更新日2019-04-24
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献RET Functions as a Dual-Specificity Kinase that Requires Allosteric Inputs from Juxtamembrane Elements.
Cell Rep, 17, 2016
5FN4
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BU of 5fn4 by Molmil
Cryo-EM structure of gamma secretase in class 2 of the apo- state ensemble
分子名称: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
著者Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
登録日2015-11-10
公開日2015-12-16
最終更新日2019-09-11
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
8HGF
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BU of 8hgf by Molmil
Human PKM2 mutant - C326S
分子名称: Pyruvate kinase PKM
著者Chen, Y.-C, Lin, K.-T, Cheng, H.-C.
登録日2022-11-14
公開日2023-11-15
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Human PKM2 mutant - C326S
To Be Published
8HKI
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BU of 8hki by Molmil
Human TRiC open state
分子名称: ADENOSINE-5'-DIPHOSPHATE, T-complex protein 1 subunit alpha, T-complex protein 1 subunit beta, ...
著者Cong, Y, Liu, C.X.
登録日2022-11-27
公開日2023-12-13
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Pathway and mechanism of tubulin folding mediated by TRiC/CCT conjugated with its ATPase cycle revealed by cryo-EM
To Be Published
5FLX
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BU of 5flx by Molmil
Mammalian 40S HCV-IRES complex
分子名称: 18S RRNA, 40S RIBOSOMAL PROTEIN S10, 40S RIBOSOMAL PROTEIN S11, ...
著者Yamamoto, H, Collier, M, Loerke, J, Ismer, J, Schmidt, A, Hilal, T, Sprink, T, Yamamoto, K, Mielke, T, Burger, J, Shaikh, T.R, Dabrowski, M, Hildebrand, P.W, Scheerer, P, Spahn, C.M.T.
登録日2015-10-28
公開日2015-12-23
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Molecular Architecture of the Ribosome-Bound Hepatitis C Virus Internal Ribosomal Entry Site RNA.
Embo J., 34, 2015
8HQ5
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BU of 8hq5 by Molmil
G6 in complex with CRM1-Ran-RanBP1
分子名称: 3-[(4-bromophenyl)carbonylamino]-4-[4-(5-chloranyl-2-methyl-phenyl)piperazin-1-yl]benzoic acid, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ...
著者Sun, Q, Lei, Y.
登録日2022-12-13
公開日2023-12-20
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献F1 in complex with CRM1-Ran-RanBP1
To Be Published
5FWK
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BU of 5fwk by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日2016-02-17
公開日2016-07-06
最終更新日2019-08-21
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
8HQ4
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BU of 8hq4 by Molmil
B27 in complex with CRM1-Ran-RanBP1
分子名称: 3-[(4-fluorophenyl)carbonylamino]-4-[4-[3-(trifluoromethyl)phenyl]piperazin-1-yl]benzoic acid, CHLORIDE ION, CRM1 isoform 1, ...
著者Lei, Y, Sun, Q.
登録日2022-12-13
公開日2023-12-20
実験手法X-RAY DIFFRACTION (2.12 Å)
主引用文献B27 in complex with CRM1-Ran-RanBP1
To Be Published
8HUF
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BU of 8huf by Molmil
B28 in complex with CRM1-Ran-RanBP1
分子名称: 3-[(4-chlorophenyl)carbonylamino]-4-[4-(2,5-dimethylphenyl)piperazin-1-yl]benzoic acid, BROMIDE ION, CHLORIDE ION, ...
著者Sun, Q, Lei, Y.
登録日2022-12-23
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献B28 in complex with CRM1-Ran-RanBP1
To Be Published
8HUG
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BU of 8hug by Molmil
F1 in complex with CRM1-Ran-RanBP1
分子名称: 4-[4-(3-chlorophenyl)piperazin-1-yl]-3-[(3-fluorophenyl)sulfonylamino]benzoic acid, CHLORIDE ION, CRM1 isoform 1, ...
著者Sun, Q, Lei, Y.
登録日2022-12-23
公開日2023-12-27
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献F1 in complex with CRM1-Ran-RanBP1
To Be Published
5FWP
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BU of 5fwp by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日2016-02-18
公開日2016-10-26
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (7.2 Å)
主引用文献Atomic Structure of Hsp90:Cdc37:Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
5FN5
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BU of 5fn5 by Molmil
Cryo-EM structure of gamma secretase in class 3 of the apo- state ensemble
分子名称: Gamma-secretase subunit APH-1A, Gamma-secretase subunit PEN-2, Nicastrin, ...
著者Bai, X.C, Rajendra, E, Yang, G.H, Shi, Y.G, Scheres, S.H.W.
登録日2015-11-10
公開日2015-12-16
最終更新日2019-09-11
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Sampling the conformational space of the catalytic subunit of human gamma-secretase.
Elife, 4, 2015
5FWL
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BU of 5fwl by Molmil
Atomic cryoEM structure of Hsp90-Cdc37-Cdk4 complex
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CYCLIN-DEPENDENT KINASE 4, HEAT SHOCK PROTEIN HSP 90 BETA, ...
著者Verba, K.A, Wang, R.Y.R, Arakawa, A, Liu, Y, Yokoyama, S, Agard, D.A.
登録日2016-02-18
公開日2016-07-06
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (9 Å)
主引用文献Atomic Structure of Hsp90-Cdc37-Cdk4 Reveals that Hsp90 Traps and Stabilizes an Unfolded Kinase.
Science, 352, 2016
6LA8
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BU of 6la8 by Molmil
349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0
分子名称: CALCIUM ION, DNA (349-MER), Histone H1.0, ...
著者Adhireksan, Z, Lee, P.L, Sharma, D, Davey, C.A.
登録日2019-11-12
公開日2020-10-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Near-atomic resolution structures of interdigitated nucleosome fibres.
Nat Commun, 11, 2020
6KVD
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BU of 6kvd by Molmil
Crystal structure of human nucleosome containing H2A.J
分子名称: CHLORIDE ION, DNA (146-MER), Histone H2A.J, ...
著者Tanaka, H, Koyama, M, Sato, S, Kujirai, T, Kurumizaka, H.
登録日2019-09-04
公開日2019-12-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.21 Å)
主引用文献Biochemical and structural analyses of the nucleosome containing human histone H2A.J.
J.Biochem., 167, 2020
6L4A
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BU of 6l4a by Molmil
H3-H3-H3 tri-nucleosome with the 22 base-pair linker DNA
分子名称: DNA (485-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Takizawa, Y, Ho, C.-H, Tachiwana, H, Matsunami, H, Ohi, M, Wolf, M, Kurumizaka, H.
登録日2019-10-16
公開日2019-12-04
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (12.3 Å)
主引用文献Cryo-EM Structures of Centromeric Tri-nucleosomes Containing a Central CENP-A Nucleosome.
Structure, 28, 2020
6LA9
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BU of 6la9 by Molmil
349 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0 (high cryoprotectant)
分子名称: CALCIUM ION, DNA (349-MER), Histone H1.0, ...
著者Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A.
登録日2019-11-12
公開日2020-10-07
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.7 Å)
主引用文献Near-atomic resolution structures of interdigitated nucleosome fibres.
Nat Commun, 11, 2020
6L9Z
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BU of 6l9z by Molmil
338 bp di-nucleosome assembled with linker histone H1.X
分子名称: CALCIUM ION, CHLORIDE ION, DNA (338-MER), ...
著者Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A.
登録日2019-11-11
公開日2021-02-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
6LAB
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BU of 6lab by Molmil
169 bp nucleosome, harboring cohesive DNA termini, assembled with linker histone H1.0
分子名称: CALCIUM ION, CHLORIDE ION, DNA (169-MER), ...
著者Adhireksan, Z, Sharma, D, Bao, Q, Lee, P.L, Padavattan, S, Davey, C.A.
登録日2019-11-12
公開日2021-02-17
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
6LA2
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BU of 6la2 by Molmil
343 bp di-nucleosome harboring cohesive DNA termini assembled with linker histone H1.0
分子名称: DNA (343-MER), Histone H1.0, Histone H2A type 1-B/E, ...
著者Adhireksan, Z, Sharma, D, Lee, P.L, Davey, C.A.
登録日2019-11-11
公開日2021-02-17
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.89 Å)
主引用文献Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
6LER
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BU of 6ler by Molmil
169 bp nucleosome harboring non-identical cohesive DNA termini.
分子名称: CALCIUM ION, DNA (169-MER), Histone H2A type 1-B/E, ...
著者Sharma, D, Adhireksan, Z, Lee, P.L, Davey, C.A.
登録日2019-11-26
公開日2021-03-03
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Engineering nucleosomes for generating diverse chromatin assemblies.
Nucleic Acids Res., 49, 2021
6LU8
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BU of 6lu8 by Molmil
Cryo-EM structure of a human pre-60S ribosomal subunit - state A
分子名称: 28S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N.
登録日2020-01-26
公開日2020-08-26
実験手法ELECTRON MICROSCOPY (3.13 Å)
主引用文献Structural snapshots of human pre-60S ribosomal particles before and after nuclear export.
Nat Commun, 11, 2020
1YWT
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BU of 1ywt by Molmil
Crystal structure of the human sigma isoform of 14-3-3 in complex with a mode-1 phosphopeptide
分子名称: 14-3-3 protein sigma, CALCIUM ION, synthetic optimal phosphopeptide (mode-1)
著者Wilker, E.W, Grant, R.A, Artim, S.C, Yaffe, M.B.
登録日2005-02-18
公開日2005-03-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A structural basis for 14-3-3sigma functional specificity.
J.Biol.Chem., 280, 2005
2C9A
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BU of 2c9a by Molmil
Crystal structure of the MAM-Ig module of receptor protein tyrosine phosphatase mu
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, RECEPTOR-TYPE TYROSINE-PROTEIN PHOSPHATASE MU, ...
著者Aricescu, A.R, Hon, W.C, Siebold, C, Lu, W, Van Der Merwe, P.A, Jones, E.Y.
登録日2005-12-09
公開日2006-01-19
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Molecular Analysis of Receptor Protein Tyrosine Phosphatase Mu-Mediated Cell Adhesion.
Embo J., 25, 2006

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