PDB: 13252 件ウェブページステータス検索Chemie searchBIRD

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8FOJ	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the post RNA handoff state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.8 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8FOH	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase complex in the RNA synthesis state 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (4.6 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
3HHN	Crystal structure of class I ligase ribozyme self-ligation product, in complex with U1A RBD 分子名称: Class I ligase ribozyme, self-ligation product, MAGNESIUM ION, ... 著者 Shechner, D.M, Grant, R.A, Bagby, S.C, Bartel, D.P. 登録日 2009-05-15 公開日 2009-11-24 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.987 Å) 主引用文献 Crystal structure of the catalytic core of an RNA-polymerase ribozyme. Science, 326, 2009
6H02	Crystal structure of human Mediator subunit MED23 分子名称: LAMA nanobody NB106, Mediator of RNA polymerase II transcription subunit 23 著者 Clantin, B, Monte, D, Villeret, V. 登録日 2018-07-06 公開日 2018-08-29 最終更新日 2018-09-05 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Crystal structure of human Mediator subunit MED23. Nat Commun, 9, 2018
6T9L	SAGA DUB module bound to a ubiqitinated nucleosome 分子名称: Histone H2A, Histone H2B, Histone H2B 1.1, ... 著者 Wang, H, Cramer, P. 登録日 2019-10-28 公開日 2020-01-29 最終更新日 2024-05-22 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the transcription coactivator SAGA. Nature, 577, 2020
8D71	Human Ago2 bound to miR122(21nt) 分子名称: MAGNESIUM ION, Protein argonaute-2, miR-122-21nt 著者 Xiao, Y, MacRae, I. 登録日 2022-06-07 公開日 2023-05-03 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 A tiny loop in the Argonaute PIWI domain tunes small RNA seed strength. Embo Rep., 24, 2023
6UEB	Structure of Rabies SAD-B19 L-P complex from cryo-EM 分子名称: Large structural protein, Phosphoprotein,Phosphoprotein, ZINC ION 著者 Horwitz, J.A, Harrison, S.C. 登録日 2019-09-20 公開日 2020-02-05 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Structure of a rabies virus polymerase complex from electron cryo-microscopy. Proc.Natl.Acad.Sci.USA, 117, 2020
5EHG	DENGUE 3 NS5 METHYLTRANSFERASE BOUND TO S-ADENOSYL METHIONINE AND MOLECULE BF341 分子名称: 4-[3-[(2-azanyl-4-chloranyl-phenyl)carbamoylamino]phenyl]sulfonyloxybenzoic acid, RNA-directed RNA polymerase NS5, S-ADENOSYLMETHIONINE 著者 Barral, K, Bricogne, G, Sharff, A. 登録日 2015-10-28 公開日 2016-10-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Discovery of novel dengue virus NS5 methyltransferase non-nucleoside inhibitors by fragment-based drug design. Eur.J.Med.Chem., 125, 2016
8FOC	Cryo-EM structure of S. cerevisiae DNA polymerase alpha-primase in Apo state conformation I 分子名称: DNA polymerase, DNA polymerase alpha subunit B, DNA primase, ... 著者 Yuan, Z, Georgescu, R, Li, H, O'Donnell, M. 登録日 2022-12-30 公開日 2023-05-31 最終更新日 2024-03-13 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Molecular choreography of primer synthesis by the eukaryotic Pol alpha-primase. Nat Commun, 14, 2023
8VRD	Rigid body fitted model for free recombinant gamma tubulin ring complex. 分子名称: Actin, cytoplasmic 1, Gamma-tubulin complex component 3, ... 著者 Aher, A, Urnavicius, L, Kapoor, T.M. 登録日 2024-01-21 公開日 2024-03-27 実験手法 ELECTRON MICROSCOPY (7 Å) 主引用文献 Rigid body fitted model for free recombinant gamma tubulin ring complex. To be published
2W9B	Binary complex of Dpo4 bound to N2,N2-dimethyl-deoxyguanosine modified DNA 分子名称: 5'-D(*GP*GP*GP*GP*GP*AP*AP*GP*GP*AP *TP*TP*CP*DOCP)-3', 5'-D(*TP*CP*AP*TP*M2GP*GP*AP*AP*TP*CP*CP *TP*TP*CP*CP*CP*CP*C)-3', DNA POLYMERASE IV, ... 著者 Eoff, R.L, Zhang, H, Kosekov, I.D, Rizzo, C.J, Egli, M, Guengerich, F.P. 登録日 2009-01-22 公開日 2009-05-12 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.28 Å) 主引用文献 Structure-Function Relationships in Miscoding by Sulfolobus Solfataricus DNA Polymerase Dpo4: Guanine N2,N2-Dimethyl Substitution Produces Inactive and Miscoding Polymerase Complexes. J.Biol.Chem., 284, 2009
6U1X	Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor (3.0 A resolution) 分子名称: Phosphoprotein, RNA-directed RNA polymerase L, ZINC ION 著者 Jenni, S, Bloyet, L.M, Dias-Avalos, R, Liang, B, Wheelman, S.P.J, Grigorieff, N, Harrison, S.C. 登録日 2019-08-17 公開日 2020-01-22 最終更新日 2024-03-20 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structure of the Vesicular Stomatitis Virus L Protein in Complex with Its Phosphoprotein Cofactor. Cell Rep, 30, 2020
7R08	Abortive infection DNA polymerase Abi-P2 分子名称: Reverse transcriptase 著者 Gapinska, M.A, Figiel, M, Czarnocki Cieciura, M, Nowotny, M, Zajko, W. 登録日 2022-02-01 公開日 2022-09-07 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Mechanism of protein-primed template-independent DNA synthesis by Abi polymerases. Nucleic Acids Res., 50, 2022
8ASG	Structure of the SFTSV L protein bound in a resting state [RESTING] 分子名称: MAGNESIUM ION, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*AP*UP*GP*A*)-3'), RNA (5'-R(*GP*AP*UP*CP*UP*GP*GP*GP*CP*GP*GP*UP*CP*UP*UP*UP*GP*UP*GP*U*)-3'), ... 著者 Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. 登録日 2022-08-19 公開日 2023-01-18 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
8ASB	Structure of the SFTSV L protein stalled at early elongation with the endonuclease domain in a raised conformation [EARLY-ELONGATION-ENDO] 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, RNA (5'-R(*AP*CP*AP*CP*AP*GP*AP*GP*AP*CP*GP*CP*CP*CP*AP*GP*A)-3'), ... 著者 Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. 登録日 2022-08-18 公開日 2023-01-18 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
8AS7	Structure of the SFTSV L protein stalled at early elongation [EARLY-ELONGATION] 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, MAGNESIUM ION, ... 著者 Williams, H.M, Thorkelsson, S.R, Vogel, D, Milewski, M, Busch, C, Cusack, S, Grunewald, K, Quemin, E.R.J, Rosenthal, M. 登録日 2022-08-18 公開日 2023-01-18 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 Structural insights into viral genome replication by the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 51, 2023
8D5V	WhiB6 bound to the SigmaAr4-RNAP Beta flap tip chimera 分子名称: IRON/SULFUR CLUSTER, Probable transcriptional regulator WhiB6, RNA polymerase sigma factor SigA,DNA-directed RNA polymerase subunit beta 著者 Wan, T, Zhang, L.M. 登録日 2022-06-06 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of WhiB6 and SigA4-betaTip complex To Be Published
4KRE	Structure of Human Argonaute-1 bound to endogenous Sf9 RNA 分子名称: Protein argonaute-1, RNA (5'-R(P*AP*AP*UP*AP*UP*UP*AP*AP*A*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3') 著者 Faehnle, C.R, Elkayam, E, Joshua-Tor, L. 登録日 2013-05-16 公開日 2013-06-19 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.754 Å) 主引用文献 The making of a slicer: activation of human argonaute-1. Cell Rep, 3, 2013
4KXT	Structure of human ARGONAUTE1 in complex with guide RNA 分子名称: Protein argonaute-1, RNA 著者 Nakanishi, K, Patel, D.J. 登録日 2013-05-28 公開日 2013-07-31 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.294 Å) 主引用文献 Eukaryote-Specific Insertion Elements Control Human ARGONAUTE Slicer Activity. Cell Rep, 3, 2013
7CYQ	Cryo-EM structure of an extended SARS-CoV-2 replication and transcription complex reveals an intermediate state in cap synthesis 分子名称: GUANOSINE-5'-DIPHOSPHATE, Helicase, MAGNESIUM ION, ... 著者 Yan, L, Ge, J, Zheng, L, Zhang, Y, Gao, Y, Wang, T, Wang, H, Huang, Y, Li, M, Wang, Q, Rao, Z, Lou, Z. 登録日 2020-09-04 公開日 2020-12-09 最終更新日 2024-03-27 実験手法 ELECTRON MICROSCOPY (2.83 Å) 主引用文献 Cryo-EM Structure of an Extended SARS-CoV-2 Replication and Transcription Complex Reveals an Intermediate State in Cap Synthesis. Cell, 184, 2021
6G0R	Crystal Structure of the first bromodomain of human BRD4 in complex with an acetylated POLR2A peptide (K775ac/K778ac) 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, DNA-directed RNA polymerase II subunit RPB1 著者 Filippakopoulos, P, Picaud, S, Pike, A.C.W, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C. 登録日 2018-03-19 公開日 2018-11-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Interactome Rewiring Following Pharmacological Targeting of BET Bromodomains. Mol. Cell, 73, 2019
6XYA	Cap-binding domain of SFTSV L protein 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, RNA-dependent RNA polymerase, SODIUM ION 著者 Gogrefe, N, Guenther, S, Rosenthal, M. 登録日 2020-01-30 公開日 2020-04-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Structural and functional characterization of the severe fever with thrombocytopenia syndrome virus L protein. Nucleic Acids Res., 48, 2020
4ES5	Crystal structure of the cap-binding domain of polymerase basic protein 2 from influenza virus A/Bar-headed Gs/Qinghai/15c/2005 (h5n1) with bound m7GTP 分子名称: 7N-METHYL-8-HYDROGUANOSINE-5'-TRIPHOSPHATE, Polymerase basic subunit 2, SULFATE ION 著者 Meng, G, Liu, Y, Zheng, X. 登録日 2012-04-22 公開日 2013-03-06 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural and functional characterization of K339T substitution identified in the PB2 subunit cap-binding pocket of influenza A virus J.Biol.Chem., 288, 2013
8BY6	Structure of the human nuclear cap-binding complex bound to NCBP3(560-620) and cap-analogue m7GpppG 分子名称: 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE-5'-GUANOSINE, Nuclear cap-binding protein subunit 1, Nuclear cap-binding protein subunit 2, ... 著者 Dubiez, E, Pellegrini, E, Foucher, A.E, Cusack, S, Kadlec, J. 登録日 2022-12-12 公開日 2024-01-24 最終更新日 2024-01-31 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Structural basis for competitive binding of productive and degradative co-transcriptional effectors to the nuclear cap-binding complex. Cell Rep, 43, 2024
5A53	Crystal Structure of the Rpf2-Rrs1 complex 分子名称: REGULATOR OF RIBOSOME BIOSYNTHESIS, RIBOSOME BIOGENESIS PROTEIN RPF2, SULFATE ION 著者 Madru, C, Lebaron, S, Blaud, M, Delbos, L, Rety, S, Leulliot, N. 登録日 2015-06-16 公開日 2015-10-21 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.401 Å) 主引用文献 Chaperoning 5S RNA Assembly. Genes Dev., 29, 2015

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