4CT1
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![BU of 4ct1 by Molmil](/molmil-images/mine/4ct1) | Human PDK1-PKCzeta Kinase Chimera in Complex with Allosteric Compound PS315 Bound to the PIF-Pocket | 分子名称: | (2Z)-3-(biphenyl-4-yl)-5-(4-chlorophenyl)pent-2-enoic acid, 3-PHOSPHOINOSITIDE-DEPENDENT PROTEIN KINASE 1, ADENOSINE-5'-TRIPHOSPHATE, ... | 著者 | Schulze, J.O, Zhang, H, Lopez-Garcia, L.A, Biondi, R.M. | 登録日 | 2014-03-11 | 公開日 | 2014-05-28 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Molecular Mechanism of Regulation of the Atypical Protein Kinase C by N-Terminal Domains and an Allosteric Small Compound. Chem.Biol., 21, 2014
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4CGL
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![BU of 4cgl by Molmil](/molmil-images/mine/4cgl) | Leishmania major N-myristoyltransferase in complex with an aminoacylpyrrolidine inhibitor | 分子名称: | (3R)-3-azanyl-4-(4-chlorophenyl)-1-[(3S,4R)-3-(4-chlorophenyl)-4-(hydroxymethyl)pyrrolidin-1-yl]butan-1-one, GLYCYLPEPTIDE N-TETRADECANOYLTRANSFERASE, MAGNESIUM ION, ... | 著者 | Brannigan, J.A, Roberts, S.M, Bell, A.S, Hutton, J.A, Smith, D.F, Tate, E.W, Leatherbarrow, R.J, Wilkinson, A.J. | 登録日 | 2013-11-25 | 公開日 | 2014-07-09 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Diverse Modes of Binding in Structures of Leishmania Major N-Myristoyltransferase with Selective Inhibitors Iucrj, 1, 2014
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3MBS
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![BU of 3mbs by Molmil](/molmil-images/mine/3mbs) | Crystal structure of 8mer PNA | 分子名称: | 1,2-ETHANEDIOL, Peptide Nucleic Acid | 著者 | Yeh, J.I, Pohl, E, Truan, D, He, W, Sheldrick, G.M, Achim, C. | 登録日 | 2010-03-26 | 公開日 | 2011-03-30 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.27 Å) | 主引用文献 | The crystal structure of non-modified and bipyridine-modified PNA duplexes. Chemistry, 16, 2010
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4NEN
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![BU of 4nen by Molmil](/molmil-images/mine/4nen) | An internal ligand-bound, metastable state of a leukocyte integrin, aXb2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ... | 著者 | Sen, M, Yuki, K, Springer, T.A. | 登録日 | 2013-10-29 | 公開日 | 2014-01-15 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.9012 Å) | 主引用文献 | An internal ligand-bound, metastable state of a leukocyte integrin, alpha X beta 2. J.Cell Biol., 203, 2013
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4NFO
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![BU of 4nfo by Molmil](/molmil-images/mine/4nfo) | Crystal Structure Analysis of the 16mer GCAGACUUAAGUCUGC | 分子名称: | GCAGACUUAAGUCUGC, SPERMINE | 著者 | Beal, P.A, Fisher, A.J, Phelps, K.J, Ibarra-Soza, J.M, Zheng, Y. | 登録日 | 2013-10-31 | 公開日 | 2014-07-02 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Click Modification of RNA at Adenosine: Structure and Reactivity of 7-Ethynyl- and 7-Triazolyl-8-aza-7-deazaadenosine in RNA. Acs Chem.Biol., 9, 2014
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4CGS
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![BU of 4cgs by Molmil](/molmil-images/mine/4cgs) | Crystal structure of the N-terminal domain of the PA subunit of Dhori virus polymerase | 分子名称: | GLYCEROL, POLYMERASE SUBUNIT PA | 著者 | Guilligay, D, Kadlec, J, Crepin, T, Lunardi, T, Bouvier, D, Kochs, G, Ruigrok, R.W.H, Cusack, S. | 登録日 | 2013-11-26 | 公開日 | 2014-02-05 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Comparative Structural and Functional Analysis of Orthomyxovirus Polymerase CAP-Snatching Domains. Plos One, 9, 2014
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3M75
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3M8E
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4BL9
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![BU of 4bl9 by Molmil](/molmil-images/mine/4bl9) | Crystal structure of full-length human Suppressor of fused (SUFU) mutant lacking a regulatory subdomain (crystal form I) | 分子名称: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose | 著者 | Cherry, A.L, Finta, C, Karlstrom, M, Toftgard, R, Jovine, L. | 登録日 | 2013-05-02 | 公開日 | 2013-11-27 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation Acta Crystallogr.,Sect.D, 69, 2013
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3K4X
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![BU of 3k4x by Molmil](/molmil-images/mine/3k4x) | Eukaryotic Sliding Clamp PCNA Bound to DNA | 分子名称: | DNA (5'-D(*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), DNA (5'-D(*TP*TP*TP*TP*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), Proliferating cell nuclear antigen | 著者 | McNally, R, Kuriyan, J. | 登録日 | 2009-10-06 | 公開日 | 2010-02-16 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.98 Å) | 主引用文献 | Analysis of the role of PCNA-DNA contacts during clamp loading. Bmc Struct.Biol., 10, 2010
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4PCN
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![BU of 4pcn by Molmil](/molmil-images/mine/4pcn) | Phosphotriesterase variant R22 | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Phosphotriesterase variant PTE-R22, ZINC ION | 著者 | Jackson, C.J, Campbell, E, Kaltenbach, M, Tokuriki, N. | 登録日 | 2014-04-16 | 公開日 | 2015-05-06 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | The role of protein dynamics in the evolution of new enzyme function. Nat. Chem. Biol., 12, 2016
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3K7P
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3K94
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![BU of 3k94 by Molmil](/molmil-images/mine/3k94) | Crystal Structure of Thiamin pyrophosphokinase from Geobacillus thermodenitrificans, Northeast Structural Genomics Consortium Target GtR2 | 分子名称: | Thiamin pyrophosphokinase | 著者 | Kuzin, A, Su, M, Seetharaman, J, Janjua, J, Xiao, R, Patel, D.J, Ciccosanti, C, Lee, D, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2009-10-15 | 公開日 | 2010-02-09 | 最終更新日 | 2019-07-17 | 実験手法 | X-RAY DIFFRACTION (2.101 Å) | 主引用文献 | Northeast Structural Genomics Consortium Target GtR2 To be Published
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4BLB
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![BU of 4blb by Molmil](/molmil-images/mine/4blb) | Crystal structure of a human Suppressor of fused (SUFU)-GLI1p complex | 分子名称: | MALTOSE-BINDING PERIPLASMIC PROTEIN, SUPPRESSOR OF FUSED HOMOLOG, ZINC FINGER PROTEIN GLI1, ... | 著者 | Cherry, A.L, Finta, C, Karlstrom, M, De Sanctis, D, Toftgard, R, Jovine, L. | 登録日 | 2013-05-02 | 公開日 | 2013-11-27 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural Basis of Sufu-GLI Interaction in Hedgehog Signalling Regulation Acta Crystallogr.,Sect.D, 69, 2013
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4B9J
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![BU of 4b9j by Molmil](/molmil-images/mine/4b9j) | Structure of self-complemented CssA subunit of enterotoxigenic Escherichia coli colonization factor CS6 | 分子名称: | CS6 FIMBRIAL SUBUNIT A | 著者 | Roy, S.P, Rahman, M.M, Yu, X.D, Tuittila, M, Knight, S.D, Zavialov, A.V. | 登録日 | 2012-09-04 | 公開日 | 2012-11-07 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.542 Å) | 主引用文献 | Crystal Structure of Enterotoxigenic Escherichia Coli Colonization Factor Cs6 Reveals a Novel Type of Functional Assembly. Mol.Microbiol., 86, 2012
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4BAG
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4P2Y
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4FIH
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4B9K
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![BU of 4b9k by Molmil](/molmil-images/mine/4b9k) | pVHL-ELOB-ELOC complex_(2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide bound | 分子名称: | (2S,4R)-1-(3-amino-2-methylbenzoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide, ACETATE ION, TRANSCRIPTION ELONGATION FACTOR B POLYPEPTIDE 1, ... | 著者 | Buckley, D.L, Gustafson, J.L, VanMolle, I, Roth, A.G, SeopTae, H, Gareiss, P.C, Jorgensen, W.L, Ciulli, A, Crews, C.M. | 登録日 | 2012-09-05 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Small-Molecule Inhibitors of the Interaction between the E3 Ligase Vhl and Hif1 Alpha Angew.Chem.Int.Ed.Engl., 51, 2012
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4BIS
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![BU of 4bis by Molmil](/molmil-images/mine/4bis) | JMJD2A COMPLEXED WITH 8-HYDROXYQUINOLINE-4-CARBOXYLIC ACID | 分子名称: | 8-hydroxyquinoline-4-carboxylic acid, CHLORIDE ION, GLYCEROL, ... | 著者 | Chowdhury, R, Thinnes, C, Schofield, C.J. | 登録日 | 2013-04-12 | 公開日 | 2014-02-05 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.493 Å) | 主引用文献 | 5-Carboxy-8-hydroxyquinoline is a Broad Spectrum 2-Oxoglutarate Oxygenase Inhibitor which Causes Iron Translocation. Chem Sci, 4, 2013
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4BIE
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![BU of 4bie by Molmil](/molmil-images/mine/4bie) | Crystal Structures of Ask1-inhibitor Complexes | 分子名称: | GLYCEROL, MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, N-(2-aminoethyl)-5-{2-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamide | 著者 | Singh, O, Shillings, A, Craggs, P, Wall, I, Rowland, P, Skarzynski, T, Hobbs, C.I, Hardwick, P, Tanner, R, Blunt, M, Witty, D.R, Smith, K.J. | 登録日 | 2013-04-10 | 公開日 | 2013-07-03 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. Protein Sci., 22, 2013
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4BAB
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![BU of 4bab by Molmil](/molmil-images/mine/4bab) | Redesign of a Phenylalanine Aminomutase into a beta-Phenylalanine Ammonia Lyase | 分子名称: | PHENYLALANINE AMINOMUTASE | 著者 | Bartsch, S, Wybenga, G.G, Jansen, M, Heberling, M.M, Wu, B, Dijkstra, B.W, Janssen, D.B. | 登録日 | 2012-09-12 | 公開日 | 2013-01-16 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.56 Å) | 主引用文献 | Redesign of a Phenylalanine Aminomutase Into a Phenylalanine Ammonia Lyase To be Published
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3JUK
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4PMN
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![BU of 4pmn by Molmil](/molmil-images/mine/4pmn) | Crystal structure of the Mycobacterium tuberculosis Tat-secreted protein Rv2525c in complex with MES (monoclinic crystal form I) | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ... | 著者 | Bellinzoni, M, Haouz, A, Shepard, W, Alzari, P.M. | 登録日 | 2014-05-22 | 公開日 | 2014-10-08 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (1.44 Å) | 主引用文献 | Structural studies suggest a peptidoglycan hydrolase function for the Mycobacterium tuberculosis Tat-secreted protein Rv2525c. J.Struct.Biol., 188, 2014
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4BKT
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![BU of 4bkt by Molmil](/molmil-images/mine/4bkt) | von Hippel Lindau protein:ElonginB:ElonginC complex, in complex with (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide | 分子名称: | (2S,4R)-N-methyl-1-[2-(3-methyl-1,2-oxazol-5-yl)ethanoyl]-4-oxidanyl-pyrrolidine-2-carboxamide, ARGININE, GLUTAMIC ACID, ... | 著者 | Van Molle, I, Dias, D.M, Baud, M, Galdeano, C, Geraldes, C.F.G.C, Ciulli, A. | 登録日 | 2013-04-29 | 公開日 | 2013-11-27 | 最終更新日 | 2017-07-12 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Is NMR Fragment Screening Fine-Tuned to Assess Druggability of Protein-Protein Interactions? Acs Med.Chem.Lett., 5, 2014
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