4BIE

Crystal Structures of Ask1-inhibitor Complexes

Summary for 4BIE

Entry DOI	10.2210/pdb4bie/pdb
Related	4BF2 4BHN 4BIB 4BIC 4BID
Descriptor	MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 5, GLYCEROL, N-(2-aminoethyl)-5-{2-methyl-1H-pyrrolo[2,3-b]pyridin-4-yl}thiophene-2-sulfonamide, ... (4 entities in total)
Functional Keywords	transferase, structure based desgin
Biological source	HOMO SAPIENS (HUMAN)
Cellular location	Cytoplasm: Q99683
Total number of polymer chains	2
Total formula weight	71933.85
Authors	Singh, O.,Shillings, A.,Craggs, P.,Wall, I.,Rowland, P.,Skarzynski, T.,Hobbs, C.I.,Hardwick, P.,Tanner, R.,Blunt, M.,Witty, D.R.,Smith, K.J. (deposition date: 2013-04-10, release date: 2013-07-03, Last modification date: 2023-12-20)
Primary citation	Singh, O.,Shillings, A.,Craggs, P.,Wall, I.,Rowland, P.,Skarzynski, T.,Hobbs, C.I.,Hardwick, P.,Tanner, R.,Blunt, M.,Witty, D.R.,Smith, K.J. Crystal Structures of Ask1-Inhibtor Complexes Provide a Platform for Structure Based Drug Design. Protein Sci., 22:1071-, 2013 Cited by PubMed: 23776076 DOI: 10.1002/PRO.2298 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.36 Å)

Structure validation