4ELU
 
 | | Snapshot of the large fragment of DNA polymerase I from Thermus Aquaticus processing modified pyrimidines | | 分子名称: | 2'-deoxy-5-[(4-ethynylphenyl)ethynyl]cytidine 5'-(tetrahydrogen triphosphate), ACETATE ION, DNA (5'-D(*AP*AP*AP*GP*CP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... | | 著者 | Marx, A, Diederichs, K, Obeid, S. | | 登録日 | 2012-04-11 | | 公開日 | 2013-03-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Interactions of non-polar and "Click-able" nucleotides in the confines of a DNA polymerase active site.
Chem.Commun.(Camb.), 48, 2012
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3KXD
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4O8F
 | | Crystal Structure of the complex between PPARgamma mutant R357A and rosiglitazone | | 分子名称: | 2,4-THIAZOLIDIINEDIONE, 5-[[4-[2-(METHYL-2-PYRIDINYLAMINO)ETHOXY]PHENYL]METHYL]-(9CL), Peroxisome proliferator-activated receptor gamma | | 著者 | Pochetti, G, Montanari, R, Capelli, D, Chiaraluce, R, Consalvi, V, Lori, C, Loiodice, F, Laghezza, A, Pasquo, A, Cervoni, L, Aschi, M. | | 登録日 | 2013-12-27 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis of the transactivation deficiency of the human PPAR gamma F360L mutant associated with familial partial lipodystrophy.
Acta Crystallogr.,Sect.D, 70, 2014
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4AYC
 | | RNF8 RING domain structure | | 分子名称: | CHLORIDE ION, E3 UBIQUITIN-PROTEIN LIGASE RNF8, GLYCEROL, ... | | 著者 | Mattiroli, F, Vissers, J.H.A, Van Dijk, W.J, Ikpa, P, Citterio, E, Vermeulen, W, Marteijn, J.A, Sixma, T.K. | | 登録日 | 2012-06-20 | | 公開日 | 2012-09-26 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Rnf168 Ubiquitinates K13-15 on H2A/H2Ax to Drive DNA Damage Signaling
Cell(Cambridge,Mass.), 150, 2012
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4OB7
 | | Crystal structure of esterase rPPE mutant W187H | | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, Alpha/beta hydrolase fold-3 domain protein, DI(HYDROXYETHYL)ETHER | | 著者 | Dou, S, Kong, X.D, Ma, B.D, Xu, J.H, Zhou, J.H. | | 登録日 | 2014-01-07 | | 公開日 | 2014-07-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal structures of Pseudomonas putida esterase reveal the functional role of residues 187 and 287 in substrate binding and chiral recognition
Biochem.Biophys.Res.Commun., 446, 2014
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3KNG
 | | Crystal structure of SnoaB, a cofactor-independent oxygenase from Streptomyces nogalater, determined to 1.9 resolution | | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, SULFATE ION, ... | | 著者 | Koskiniemi, H, Grocholski, T, Lindqvist, Y, Mantsala, P, Niemi, J, Schneider, G. | | 登録日 | 2009-11-12 | | 公開日 | 2010-01-26 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Crystal structure of the cofactor-independent monooxygenase SnoaB from Streptomyces nogalater: implications for the reaction mechanism
Biochemistry, 49, 2010
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3KP5
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4EXT
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4OM8
 | | Crystal structure of 5-formly-3-hydroxy-2-methylpyridine 4-carboxylic acid (FHMPC) 5-dehydrogenase, an NAD+ dependent dismutase. | | 分子名称: | 3-hydroxybutyryl-coA dehydrogenase, ACETATE ION, BETA-MERCAPTOETHANOL, ... | | 著者 | Mugo, A.N, Kobayashi, J, Mikami, B, Yagi, T, Ohnishi, K. | | 登録日 | 2014-01-27 | | 公開日 | 2015-01-28 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Crystal structure of 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase, an NAD(+)-dependent dismutase from Mesorhizobium loti
Biochem.Biophys.Res.Commun., 456, 2015
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4C2L
 | | Crystal structure of endo-xylogalacturonan hydrolase from Aspergillus tubingensis | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ENDO-XYLOGALACTURONAN HYDROLASE A, ... | | 著者 | Rozeboom, H.J, Beldman, G, Schols, H.A, Dijkstra, B.W. | | 登録日 | 2013-08-19 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Crystal Structure of Endo-Xylogalacturonan Hydrolase from Aspergillus Tubingensis.
FEBS J., 280, 2013
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4EXS
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3KVD
 | | Crystal structure of the Neisseria meningitidis Factor H binding protein, fHbp (GNA1870) at 2.0 A resolution | | 分子名称: | Lipoprotein | | 著者 | Cendron, L, Veggi, D, Girardi, E, Zanotti, G. | | 登録日 | 2009-11-30 | | 公開日 | 2010-12-29 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Structure of the uncomplexed Neisseria meningitidis factor H-binding protein fHbp (rLP2086).
Acta Crystallogr.,Sect.F, 67, 2011
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3KVM
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3KVW
 | | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand | | 分子名称: | (2Z,3E)-7'-bromo-3-(hydroxyimino)-2'-oxo-1,1',2',3-tetrahydro-2,3'-biindole-5-carboxylic acid, CHLORIDE ION, Dual specificity tyrosine-phosphorylation-regulated kinase 2 | | 著者 | Filippakopoulos, P, Myrianthopoulos, V, Kritsanida, M, Magiatis, P, Skaltsounis, A.L, Soundararajan, M, Krojer, T, Gileadi, O, Hapka, E, Fedorov, O, Berridge, G, Wang, J, Shrestha, L, Vollmar, M, von Delft, F, Arrowsmith, C.H, Edwards, A, Weigelt, J, Bountra, C, Mikros, E, Knapp, S, Structural Genomics Consortium (SGC) | | 登録日 | 2009-11-30 | | 公開日 | 2010-01-05 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Crystal Structure of dual-specificity tyrosine phosphorylation regulated kinase 2 (DYRK2) in complex with an indirubin ligand
To be Published
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3KXQ
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4F0G
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4F0F
 | | Crystal Structure of the Roco4 Kinase Domain bound to AppCp from D. discoideum | | 分子名称: | PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER, Serine/threonine-protein kinase roco4 | | 著者 | Gilsbach, B.K, Vetter, I.R, Wittinghofer, A, Kortholt, A. | | 登録日 | 2012-05-04 | | 公開日 | 2012-06-27 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Roco kinase structures give insights into the mechanism of Parkinson disease-related leucine-rich-repeat kinase 2 mutations.
Proc.Natl.Acad.Sci.USA, 109, 2012
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4BNI
 | | Crystal structure of S. aureus FabI in complex with NADP and 2-(2- aminophenoxy)-5-hexylphenol | | 分子名称: | 2-(2-azanylphenoxy)-5-hexyl-phenol, ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE [NADPH], GLUTAMIC ACID, ... | | 著者 | Schiebel, J, Chang, A, Bommineni, G.R, Tonge, P.J, Kisker, C. | | 登録日 | 2013-05-15 | | 公開日 | 2013-06-05 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Rational Optimization of Drug-Target Residence Time: Insights from Inhibitor Binding to the S. Aureus Fabi Enzyme-Product Complex.
Biochemistry, 52, 2013
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4O9P
 | | Crystal structure of Thermus thermophilis transhydrogeanse domain II dimer SeMet derivative | | 分子名称: | NAD(P) transhydrogenase subunit alpha 2, NAD(P) transhydrogenase subunit beta | | 著者 | Leung, J.H, Yamaguchi, M, Moeller, A, Schurig-Briccio, L.A, Gennis, R.B, Potter, C.S, Carragher, B, Stout, C.D. | | 登録日 | 2014-01-02 | | 公開日 | 2014-06-11 | | 最終更新日 | 2015-01-28 | | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | | 主引用文献 | Structural biology. Division of labor in transhydrogenase by alternating proton translocation and hydride transfer.
Science, 347, 2015
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4OQU
 | | Structure of the SAM-I/IV riboswitch (env87(deltaU92)) | | 分子名称: | MAGNESIUM ION, S-ADENOSYLMETHIONINE, SAM-I/IV riboswitch | | 著者 | Trausch, J.J, Reyes, F.E, Edwards, A.L, Batey, R.T. | | 登録日 | 2014-02-10 | | 公開日 | 2014-06-04 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for diversity in the SAM clan of riboswitches.
Proc.Natl.Acad.Sci.USA, 111, 2014
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4CBG
 | | Pestivirus NS3 helicase | | 分子名称: | ACETATE ION, SERINE PROTEASE NS3 | | 著者 | Tortorici, M.A, Duquerroy, S, Kwok, J, Vonrhein, C, Perez, J, Lamp, B, Bricogne, G, Rumenapf, T, Vachette, P, Rey, F.A. | | 登録日 | 2013-10-14 | | 公開日 | 2015-01-21 | | 最終更新日 | 2015-10-14 | | 実験手法 | X-RAY DIFFRACTION (2.82 Å) | | 主引用文献 | X-Ray Structure of the Pestivirus Ns3 Helicase and its Conformation in Solution.
J.Virol., 89, 2015
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4ORY
 | | Three-dimensional structure of the C65A-K59A double mutant of Human lipocalin-type Prostaglandin D Synthase holo, second crystal form | | 分子名称: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, Prostaglandin-H2 D-isomerase | | 著者 | Perduca, M, Bovi, M, Bertinelli, M, Bertini, E, Destefanis, L, Carrizo, M.E, Capaldi, S, Monaco, H.L. | | 登録日 | 2014-02-12 | | 公開日 | 2014-08-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | High-resolution structures of mutants of residues that affect access to the ligand-binding cavity of human lipocalin-type prostaglandin D synthase.
Acta Crystallogr.,Sect.D, 70, 2014
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4F3Q
 | | Structure of a YebC family protein (CBU_1566) from Coxiella burnetii | | 分子名称: | SULFATE ION, Transcriptional regulatory protein CBU_1566 | | 著者 | Franklin, M.C, Cheung, J, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. | | 登録日 | 2012-05-09 | | 公開日 | 2012-06-27 | | 最終更新日 | 2016-02-10 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
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4OGR
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4BMX
 | | Native structure of futalosine hydrolase of Helicobacter pylori strain 26695 | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ADENINE, MTA/SAH NUCLEOSIDASE | | 著者 | Kim, R.Q, Offen, W.A, Stubbs, K.A, Davies, G.J. | | 登録日 | 2013-05-12 | | 公開日 | 2013-09-11 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structural Enzymology of Helicobacter Pylori Methylthioadenosine Nucleosidase in the Futalosine Pathway
Acta Crystallogr.,Sect.D, 70, 2014
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