8GWB
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![BU of 8gwb by Molmil](/molmil-images/mine/8gwb) | SARS-CoV-2 E-RTC complex with RNA-nsp9 | 分子名称: | Helicase, MANGANESE (II) ION, Non-structural protein 7, ... | 著者 | Yan, L.M, Rao, Z.H, Lou, Z.Y. | 登録日 | 2022-09-16 | 公開日 | 2022-12-07 | 最終更新日 | 2023-10-25 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | A mechanism for SARS-CoV-2 RNA capping and its inhibition by nucleotide analog inhibitors. Cell, 185, 2022
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8GW8
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![BU of 8gw8 by Molmil](/molmil-images/mine/8gw8) | the human PTH1 receptor bound to an intracellular biased agonist | 分子名称: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Isoform Gnas-2 of Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | 著者 | Kobayashi, K, Kusakizako, T, Okamoto, H.H, Nureki, O. | 登録日 | 2022-09-16 | 公開日 | 2023-06-14 | 最終更新日 | 2023-09-27 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Class B1 GPCR activation by an intracellular agonist. Nature, 618, 2023
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8GW5
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![BU of 8gw5 by Molmil](/molmil-images/mine/8gw5) | |
8GVX
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![BU of 8gvx by Molmil](/molmil-images/mine/8gvx) | Cryo-EM structure of the human TRPC5 ion channel in complex with G alpha i3 subunits, class2 | 分子名称: | (2S)-2-(hexadecanoyloxy)-3-hydroxypropyl (9Z)-octadec-9-enoate, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ... | 著者 | Won, J, Jeong, H, Lee, H.H. | 登録日 | 2022-09-16 | 公開日 | 2023-05-24 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Molecular architecture of the G alpha i -bound TRPC5 ion channel. Nat Commun, 14, 2023
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8GVM
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![BU of 8gvm by Molmil](/molmil-images/mine/8gvm) | The structure of azide-bound cytochrome C oxidase determined using the crystals exposed to 20 mm azide solution for 4 days | 分子名称: | (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ... | 著者 | Tsukihara, T, Shimada, A. | 登録日 | 2022-09-15 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.851 Å) | 主引用文献 | X-ray structural analyses of azide-bound cytochromecoxidases reveal that the H-pathway is critically important for the proton-pumping activity J. Biol. Chem., 293, 2018
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8GVI
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![BU of 8gvi by Molmil](/molmil-images/mine/8gvi) | The complex between H25-11 TCR and HLA-A24 bound to HIV-1 Nef138-8 peptide | 分子名称: | 8-mer peptide from Protein Nef, Beta-2-microglobulin, H25-11 TCR alpha chain, ... | 著者 | Gao, G.F, Shi, Y, Tan, S, Ma, K, Chai, Y, Qi, J, Kawana-Tachikawa, A, Iwamoto, A, Dong, T, Guan, J. | 登録日 | 2022-09-15 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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8GVG
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![BU of 8gvg by Molmil](/molmil-images/mine/8gvg) | The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 (2F) peptide | 分子名称: | Beta-2-microglobulin, MHC class I antigen, TD08 TCR alpha chain, ... | 著者 | Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A. | 登録日 | 2022-09-15 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.37 Å) | 主引用文献 | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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8GVB
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![BU of 8gvb by Molmil](/molmil-images/mine/8gvb) | The complex between public TCR TD08 and HLA-A24 bound to HIV-1 Nef138-8 peptide | 分子名称: | 8-mer peptide from Protein Nef, Beta-2-microglobulin, MHC class I antigen, ... | 著者 | Gao, G.F, Shi, Y, Ma, K, Chai, Y, Guan, J, Qi, J, Tan, S, Dong, T, Iwamoto, A, Kawana-Tachikawa, A. | 登録日 | 2022-09-14 | 公開日 | 2022-10-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Molecular Basis for the Recognition of HIV Nef138-8 Epitope by a Pair of Human Public T Cell Receptors. J Immunol., 209, 2022
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8GUK
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![BU of 8guk by Molmil](/molmil-images/mine/8guk) | Human nucleosome core particle (free form) | 分子名称: | DNA (147-mer), Histone H2A type 1, Histone H2B type 1-J, ... | 著者 | Onishi, S, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.51 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8GUJ
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![BU of 8guj by Molmil](/molmil-images/mine/8guj) | Bre1-nucleosome complex (Model II) | 分子名称: | DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | 著者 | Onishi, S, Sato, K, Hamada, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8GUI
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![BU of 8gui by Molmil](/molmil-images/mine/8gui) | Bre1-nucleosome complex (Model I) | 分子名称: | DNA (147-mer), E3 ubiquitin-protein ligase BRE1A, E3 ubiquitin-protein ligase BRE1B, ... | 著者 | Onishi, S, Hamada, K, Sato, K, Nishizawa, T, Nureki, O, Ogata, K, Sengoku, T. | 登録日 | 2022-09-12 | 公開日 | 2023-09-20 | 最終更新日 | 2024-04-03 | 実験手法 | ELECTRON MICROSCOPY (2.81 Å) | 主引用文献 | Structure of the human Bre1 complex bound to the nucleosome. Nat Commun, 15, 2024
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8GUH
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![BU of 8guh by Molmil](/molmil-images/mine/8guh) | Serine Palmitoyltransferase from Sphingobacterium multivorum complexed with Tris | 分子名称: | 1,2-ETHANEDIOL, Serine palmitoyltransferase, [4-[[[2-(hydroxymethyl)-1,3-bis(oxidanyl)propan-2-yl]amino]methyl]-6-methyl-5-oxidanyl-pyridin-3-yl]methyl dihydrogen phosphate | 著者 | Murakami, T, Takahashi, A, Katayama, A, Miyahara, I, Kamiya, N, Ikushiro, H, Yano, T. | 登録日 | 2022-09-12 | 公開日 | 2023-07-19 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Crystal structure of Sphingobacterium multivorum serine palmitoyltransferase complexed with tris(hydroxymethyl)aminomethane. Acta Crystallogr.,Sect.F, 78, 2022
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8GUE
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![BU of 8gue by Molmil](/molmil-images/mine/8gue) | Crystal Structure of narbomycin-bound cytochrome P450 PikC with the unnatural amino acid p-Acetyl-L-Phenylalanine incorporated at position 238 | 分子名称: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cytochrome P450 monooxygenase PikC, ... | 著者 | Li, G.B, Pan, Y.J, Li, S.Y, Gao, X. | 登録日 | 2022-09-11 | 公開日 | 2023-02-15 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Unnatural activities and mechanistic insights of cytochrome P450 PikC gained from site-specific mutagenesis by non-canonical amino acids. Nat Commun, 14, 2023
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8GUD
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![BU of 8gud by Molmil](/molmil-images/mine/8gud) | Cryo-EM structure of cancer-specific PI3Kalpha mutant E545K in complex with BYL-719 | 分子名称: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Liu, X, Zhou, Q, Hart, J.R, Xu, Y, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2022-09-11 | 公開日 | 2022-11-23 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.62 Å) | 主引用文献 | Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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8GUB
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![BU of 8gub by Molmil](/molmil-images/mine/8gub) | Cryo-EM structure of cancer-specific PI3Kalpha mutant H1047R in complex with BYL-719 | 分子名称: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Liu, X, Zhou, Q, Hart, J.R, Xu, Y, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2022-09-11 | 公開日 | 2022-11-23 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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8GUA
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![BU of 8gua by Molmil](/molmil-images/mine/8gua) | Cryo-EM structure of cancer-specific PI3Kalpha mutant E542K in complex with BYL-719 | 分子名称: | (2S)-N~1~-{4-methyl-5-[2-(1,1,1-trifluoro-2-methylpropan-2-yl)pyridin-4-yl]-1,3-thiazol-2-yl}pyrrolidine-1,2-dicarboxamide, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | 著者 | Liu, X, Zhou, Q, Hart, J.R, Xu, Y, Yang, S, Yang, D, Vogt, P.K, Wang, M.-W. | 登録日 | 2022-09-11 | 公開日 | 2022-12-07 | 最終更新日 | 2024-07-03 | 実験手法 | ELECTRON MICROSCOPY (2.77 Å) | 主引用文献 | Cryo-EM structures of cancer-specific helical and kinase domain mutations of PI3K alpha. Proc.Natl.Acad.Sci.USA, 119, 2022
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8GU7
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![BU of 8gu7 by Molmil](/molmil-images/mine/8gu7) | |
8GU3
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![BU of 8gu3 by Molmil](/molmil-images/mine/8gu3) | |
8GU0
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![BU of 8gu0 by Molmil](/molmil-images/mine/8gu0) | |
8GTX
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![BU of 8gtx by Molmil](/molmil-images/mine/8gtx) | |
8GTT
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![BU of 8gtt by Molmil](/molmil-images/mine/8gtt) | |
8GTS
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![BU of 8gts by Molmil](/molmil-images/mine/8gts) | |
8GTR
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![BU of 8gtr by Molmil](/molmil-images/mine/8gtr) | CryoEM structure of human Pannexin isoform 3 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, PHOSPHATIDYLETHANOLAMINE, Pannexin-3 | 著者 | Hussain, N, Penmatsa, A. | 登録日 | 2022-09-08 | 公開日 | 2024-02-28 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.91 Å) | 主引用文献 | Cryo-EM structures of pannexin 1 and 3 reveal differences among pannexin isoforms. Nat Commun, 15, 2024
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8GTQ
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![BU of 8gtq by Molmil](/molmil-images/mine/8gtq) | cryo-EM structure of Omicron BA.5 S protein in complex with S2L20 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Xia, X.Y, Zhang, Y.Y, Chi, X.M, Huang, B.D, Wu, L.S, Zhou, Q. | 登録日 | 2022-09-08 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against SARS-CoV-2 Omicron variants. Cell Discov, 9, 2023
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8GTP
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![BU of 8gtp by Molmil](/molmil-images/mine/8gtp) | cryo-EM structure of Omicron BA.5 S protein in complex with XGv289 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Xia, X.Y, Zhang, Y.Y, Chi, X.M, Huang, B.D, Wu, L.S, Zhou, Q. | 登録日 | 2022-09-08 | 公開日 | 2023-07-12 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Comprehensive structural analysis reveals broad-spectrum neutralizing antibodies against SARS-CoV-2 Omicron variants. Cell Discov, 9, 2023
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