PDB: 9760 件ウェブページステータス検索Chemie searchBIRD

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7SFV	CryoEM structure of Venezuelan Equine Encephalitis virus (VEEV) TC-83 strain VLP in complex with Fab hVEEV-63 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Capsid protein, Spike glycoprotein E1, ... 著者 Binshtein, E, Crowe, J.E. 登録日 2021-10-04 公開日 2022-03-16 最終更新日 2022-07-06 実験手法 ELECTRON MICROSCOPY (4 Å) 主引用文献 Neutralizing antibodies protect mice against Venezuelan equine encephalitis virus aerosol challenge. J.Exp.Med., 219, 2022
5OD0	Crystal structure of ACPA E4 分子名称: Fab fragment of ACPA E4 - Light chain, Fab fragment of ACPA E4 - heavy chain, GLYCEROL 著者 Dobritzsch, D, Ge, C, Holmdahl, R. 登録日 2017-07-04 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural Basis of Cross-Reactivity of Anti-Citrullinated Protein Antibodies. Arthritis Rheumatol, 71, 2019
4FFY	Crystal structure of DENV1-E111 single chain variable fragment bound to DENV-1 DIII, strain 16007. 分子名称: CHLORIDE ION, DENV1-E111 single chain variable fragment (heavy chain), DENV1-E111 single chain variable fragment (light chain), ... 著者 Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-06-01 公開日 2012-06-20 最終更新日 2012-10-31 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope. Plos Pathog., 8, 2012
4FFZ	Crystal Structure of DENV1-E111 fab fragment bound to DENV-1 DIII (Western Pacific-74 strain). 分子名称: DENV1-E111 fab fragment (heavy chain), DENV1-E111 fab fragment (light chain), Envelope protein E 著者 Austin, S.K, Nelson, C.A, Fremont, D.H, Center for Structural Genomics of Infectious Diseases (CSGID) 登録日 2012-06-01 公開日 2012-06-27 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Structural Basis of Differential Neutralization of DENV-1 Genotypes by an Antibody that Recognizes a Cryptic Epitope. Plos Pathog., 8, 2012
4FNK	Crystal structure of the A/Hong Kong/1/1968 (H3N2) influenza virus hemagglutinin 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ... 著者 Ekiert, D.C, Wilson, I.A. 登録日 2012-06-19 公開日 2012-09-19 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.901 Å) 主引用文献 Cross-neutralization of influenza A viruses mediated by a single antibody loop. Nature, 489, 2012
6DCQ	Ectodomain of full length, wild type HIV-1 glycoprotein clone PC64M18C043 in complex with PGT151 Fab 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)]alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Rantalainen, K. 登録日 2018-05-08 公開日 2018-06-27 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Co-evolution of HIV Envelope and Apex-Targeting Neutralizing Antibody Lineage Provides Benchmarks for Vaccine Design. Cell Rep, 23, 2018
1AY1	ANTI TAQ FAB TP7 分子名称: TP7 FAB 著者 Murali, R, Helmer-Citterich, M, Sharkey, D.J, Scalice, E.R, Daiss, J.L, Sullivan, M.A, Murthy, H.M.K. 登録日 1997-11-13 公開日 1998-05-13 最終更新日 2023-08-02 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structural studies on an inhibitory antibody against Thermus aquaticus DNA polymerase suggest mode of inhibition. Protein Eng., 11, 1998
5CEZ	Crystal Structure of the BG505 SOSIP gp140 HIV-1 Env trimer in Complex with an early putative precursor of the PGT121 family at 3.0 Angstrom 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 35022 Fab Heavy Chain, ... 著者 Wilson, I.A, Garces, F. 登録日 2015-07-08 公開日 2015-12-23 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.031 Å) 主引用文献 Affinity Maturation of a Potent Family of HIV Antibodies Is Primarily Focused on Accommodating or Avoiding Glycans. Immunity, 43, 2015
6CNV	INFLUENZA B/BRISBANE HEMAGGLUTININ FAB CR9115 SD84H COMPLEX 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CR9114 Fab heavy chain, ... 著者 Luo, J, Obmolova, G. 登録日 2018-03-09 公開日 2018-11-14 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (4.1 Å) 主引用文献 Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin. Science, 362, 2018
2QQO	Crystal Structure of the a2b1b2 Domains from Human Neuropilin-2 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, ... 著者 Appleton, B.A, Wiesmann, C. 登録日 2007-07-26 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding Embo J., 26, 2007
2QQM	Crystal Structure of the a2b1b2 Domains from Human Neuropilin-1 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... 著者 Appleton, B.A, Wiesmann, C. 登録日 2007-07-26 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding Embo J., 26, 2007
4N90	Crystal structure of ternary complex of TRAIL, DR5, and Fab fragment from a DR5 agonist antibody 分子名称: Fab heavy chain, Fab light chain, Tumor necrosis factor ligand superfamily member 10, ... 著者 Huang, X. 登録日 2013-10-18 公開日 2014-09-03 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Apo2L/TRAIL and the Death Receptor 5 Agonist Antibody AMG 655 Cooperate to Promote Receptor Clustering and Antitumor Activity. Cancer Cell, 26, 2014
8DCN	Crystal structure of Clostridioides difficile binary toxin CDTb D4 fragment in complex with BINTOXB/9 Fab 分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/9 Fab heavy chain, BINTOXB/9 Fab light chain 著者 Goldsmith, J.A, McLellan, J.S. 登録日 2022-06-16 公開日 2023-04-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin. J.Bacteriol., 205, 2023
8DCM	Crystal structure of Clostridioides difficile binary toxin proCDTb lacking D4 in complex with BINTOXB/22 Fab 分子名称: ADP-ribosylating binary toxin binding subunit CdtB, BINTOXB/22 Fab heavy chain, BINTOXB/22 Fab light chain, ... 著者 Goldsmith, J.A, McLellan, J.S. 登録日 2022-06-16 公開日 2023-04-05 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structural Basis for Binding of Neutralizing Antibodies to Clostridioides difficile Binary Toxin. J.Bacteriol., 205, 2023
8ALX	Structure of human PD-L1 in complex with inhibitor 分子名称: 3-PYRIDIN-4-YL-2,4-DIHYDRO-INDENO[1,2-.C.]PYRAZOLE, AMINOMETHYLAMIDE, ACETATE ION, ... 著者 Rodriguez, I, Grudnik, P, Holak, T, Magiera-Mularz, K. 登録日 2022-08-01 公開日 2023-08-16 最終更新日 2024-07-10 実験手法 X-RAY DIFFRACTION (1.1 Å) 主引用文献 Structural and biological characterization of pAC65, a macrocyclic peptide that blocks PD-L1 with equivalent potency to the FDA-approved antibodies. Mol Cancer, 22, 2023
2QQI	Crystal Structure of the b1b2 Domains from Human Neuropilin-1 分子名称: GLYCEROL, Neuropilin-1 著者 Appleton, B.A, Desmarais, W, Wiesmann, C. 登録日 2007-07-26 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding Embo J., 26, 2007
2QQJ	Crystal Structure of the b1b2 Domains from Human Neuropilin-2 分子名称: GLYCEROL, Neuropilin-2 著者 Appleton, B.A, Wiesmann, C. 登録日 2007-07-26 公開日 2007-11-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural studies of neuropilin/antibody complexes provide insights into semaphorin and VEGF binding Embo J., 26, 2007
7RQ6	Cryo-EM structure of SARS-CoV-2 spike in complex with non-neutralizing NTD-directed CV3-13 Fab isolated from convalescent individual 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CV3-13 Fab heavy chain, ... 著者 Chen, Y, Pozharski, E, Tolbert, W.D, Pazgier, M. 登録日 2021-08-05 公開日 2022-04-20 最終更新日 2023-08-09 実験手法 ELECTRON MICROSCOPY (4.18 Å) 主引用文献 A Fc-enhanced NTD-binding non-neutralizing antibody delays virus spread and synergizes with a nAb to protect mice from lethal SARS-CoV-2 infection. Cell Rep, 38, 2022
6XPO	Influenza hemagglutinin A/Bangkok/01/1979(H3N2) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Hemagglutinin, ... 著者 McCarthy, K.R, Harrison, S.C. 登録日 2020-07-08 公開日 2021-05-19 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 A Prevalent Focused Human Antibody Response to the Influenza Virus Hemagglutinin Head Interface. Mbio, 12, 2021
2RLL	CCR5 Nt(7-15) 分子名称: 9-mer from C-C chemokine receptor type 5 著者 Bewley, C.A, Lam, S.N. 登録日 2007-07-21 公開日 2007-09-25 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4 Science, 317, 2007
5JZ7	NGF IN COMPLEX WITH MEDI578 scFv 分子名称: Beta-nerve growth factor, MEDI578 scFv, heavy chain, ... 著者 Olsson, L.-L, Aagaard, A. 登録日 2016-05-16 公開日 2017-01-11 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.4 Å) 主引用文献 Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo. Sci Rep, 6, 2016
6FBJ	monoclonal antibody targeting Matrix metalloproteinase 7 分子名称: Heavy Chain, Light chain 著者 Dym, O. 登録日 2017-12-19 公開日 2019-01-30 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Novel monoclonal antibody targeting Matrix metalloproteinase 7 shows therapeutic potential against pancreatic cancer To Be Published
1S6N	NMR Structure of Domain III of the West Nile Virus Envelope Protein, Strain 385-99 分子名称: envelope glycoprotein 著者 Volk, D.E, Beasley, D.W, Kallick, D.A, Holbrook, M.R, Barrett, A.D, Gorenstein, D.G. 登録日 2004-01-26 公開日 2004-07-06 最終更新日 2011-07-13 実験手法 SOLUTION NMR 主引用文献 Solution Structure and Antibody Binding Studies of the Envelope Protein Domain III from the New York Strain of West Nile Virus J.Biol.Chem., 279, 2004
7KPG	Blocking Fab 25 anti-SIRP-alpha antibody in complex with SIRP-alpha Variant 1 分子名称: Heavy chain of Fab 25 anti-SIRP-alpha antibody, Light chain of Fab 25 anti-SIRP-alpha antibody, SULFATE ION, ... 著者 Sim, J, Pons, J. 登録日 2020-11-11 公開日 2020-12-16 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.27 Å) 主引用文献 Targeting the myeloid checkpoint receptor SIRP alpha potentiates innate and adaptive immune responses to promote anti-tumor activity. J Hematol Oncol, 13, 2020
2MGP	Structure of Plasmodium Yoelii Merozoite Surface Protein 1 - C-terminal Domain 分子名称: Merozoite surface protein 1 著者 Curd, R.D, Birdsall, B, Kadekoppala, M, Ogun, S, Kelly, G, Holder, A.A. 登録日 2013-11-03 公開日 2014-02-12 最終更新日 2023-06-14 実験手法 SOLUTION NMR 主引用文献 The structure of Plasmodium yoelii merozoite surface protein 119, antibody specificity and implications for malaria vaccine design OPEN BIOLOGY, 4, 2014

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