PDB: 5653 件ウェブページステータス検索Chemie searchBIRD

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2BKK	Crystal structure of Aminoglycoside Phosphotransferase APH(3')-IIIa in complex with the inhibitor AR_3a 分子名称: ADENOSINE-5'-DIPHOSPHATE, AMINOGLYCOSIDE 3'-PHOSPHOTRANSFERASE, DESIGNED ANKYRIN REPEAT INHIBITOR AR_3A, ... 著者 Kohl, A, Amstutz, P, Parizek, P, Binz, H.K, Briand, C, Capitani, G, Forrer, P, Pluckthun, A, Grutter, M.G. 登録日 2005-02-16 公開日 2005-08-09 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Allosteric Inhibition of Aminoglycoside Phosphotransferase by a Designed Ankyrin Repeat Protein Structure, 13, 2005
1RGR	Cyclic Peptides Targeting PDZ Domains of PSD-95: Structural Basis for Enhanced Affinity and Enzymatic Stability 分子名称: BETA-ALANINE, Presynaptic density protein 95, postsynaptic protein CRIPT peptide 著者 Piserchio, A, Salinas, G.D, Li, T, Marshall, J, Spaller, M.R, Mierke, D.F. 登録日 2003-11-12 公開日 2004-05-18 最終更新日 2021-10-27 実験手法 SOLUTION NMR 主引用文献 Targeting Specific PDZ Domains of PSD-95; Structural Basis for Enhanced Affinity and Enzymatic Stability of a Cyclic Peptide. Chem.Biol., 11, 2004
1RIM	E6-binding zinc finger (E6apc2) 分子名称: E6apc2 peptide 著者 Liu, Y, Liu, Z, Androphy, E, Chen, J, Baleja, J.D. 登録日 2003-11-17 公開日 2004-08-03 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Design and characterization of helical peptides that inhibit the E6 protein of papillomavirus. Biochemistry, 43, 2004
1U7M	Solution structure of a diiron protein model: Due Ferri(II) turn mutant 分子名称: Four-helix bundle model, ZINC ION 著者 Maglio, O, Nastri, F, Calhoun, J.R, Lahr, S, Pavone, V, DeGrado, W.F, Lombardi, A. 登録日 2004-08-04 公開日 2005-03-01 最終更新日 2024-05-29 実験手法 SOLUTION NMR 主引用文献 Analysis and Design of Turns in alpha-Helical Hairpins J.Mol.Biol., 346, 2005
6YMV	Cryo-EM structure of yeast mitochondrial RNA polymerase partially-melted transcription initiation complex (PmIC) 分子名称: DNA (33-MER) NON-TEMPLATE, DNA (33-MER) template, DNA-directed RNA polymerase, ... 著者 Das, K, Patel, S.S. 登録日 2020-04-10 公開日 2020-12-02 最終更新日 2023-10-18 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial RNA Polymerase. Mol.Cell, 81, 2021
1R9V	NMR Structure of a D,L-Alternating Dodecamer of Norleucine 分子名称: BOC-(D-NLE-L-NLE)4-D-NLE(METHYL)-L-NLE-D-NLE-L-NLE METHYL ESTER 著者 Navarro, E, Celda, B. 登録日 2003-10-31 公開日 2003-12-02 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Solution NMR Structure of a D,L-Alternating Oligonorleucine as a Model of Beta-Helix Biopolymers, 59, 2001
8G47	KRAS G12C complex with GDP and AMG 510 imaged on a cryo-EM imaging scaffold 分子名称: AMG 510 (bound form), GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... 著者 Castells-Graells, R, Sawaya, M.R, Yeates, T.O. 登録日 2023-02-08 公開日 2023-08-09 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.19 Å) 主引用文献 Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
8G4H	KRAS G13C complex with GDP imaged on a cryo-EM imaging scaffold 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Castells-Graells, R, Sawaya, M.R, Yeates, T.O. 登録日 2023-02-09 公開日 2023-08-09 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (2.87 Å) 主引用文献 Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
8G42	KRAS G12C complex with GDP imaged on a cryo-EM imaging scaffold 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Castells-Graells, R, Sawaya, M.R, Yeates, T.O. 登録日 2023-02-08 公開日 2023-08-09 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (3.02 Å) 主引用文献 Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
8G4F	KRAS G12V complex with GDP imaged on a cryo-EM imaging scaffold 分子名称: GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... 著者 Castells-Graells, R, Sawaya, M.R, Yeates, T.O. 登録日 2023-02-09 公開日 2023-08-09 最終更新日 2023-09-27 実験手法 ELECTRON MICROSCOPY (2.91 Å) 主引用文献 Cryo-EM structure determination of small therapeutic protein targets at 3 angstrom -resolution using a rigid imaging scaffold. Proc.Natl.Acad.Sci.USA, 120, 2023
6YMW	Cryo-EM structure of yeast mitochondrial RNA polymerase transcription initiation complex 分子名称: Chains: N, Chains: T, DNA-directed RNA polymerase, ... 著者 Das, K, Patel, S.S. 登録日 2020-04-10 公開日 2020-12-09 最終更新日 2023-10-18 実験手法 ELECTRON MICROSCOPY (3.71 Å) 主引用文献 Cryo-EM Structures Reveal Transcription Initiation Steps by Yeast Mitochondrial RNA Polymerase. Mol.Cell, 81, 2021
8QZN	DARPin-Armadillo fusion protein with a selected Tyrosin pocket binding to the fused target peptide 分子名称: 1,2-ETHANEDIOL, DARPin-Armadillo fusion protein with Tyrosin pocket and linked target peptide, SULFATE ION 著者 Stark, Y, Menard, F, Jeliazkov, J, Ernst, P, Chembath, A, Ashraf, M, Hine, A, Plueckthun, A. 登録日 2023-10-27 公開日 2024-07-03 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Modular binder technology by NGS-aided, high-resolution selection in yeast of designed armadillo modules. Proc.Natl.Acad.Sci.USA, 121, 2024
8T0G	Backbone Dialkylation in Peptide Hairpins: Natural Backbone Prototype 分子名称: Immunoglobulin G-binding protein G 著者 Heath, S.L, Horne, W.S, Lengyel, G.A. 登録日 2023-06-01 公開日 2023-08-16 実験手法 SOLUTION NMR 主引用文献 Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability. Org.Biomol.Chem., 21, 2023
8T0H	Backbone Dialkylation in Peptide Hairpins: (S)-Ethylpropylglycine variant 分子名称: Immunoglobulin G-binding protein G 著者 Heath, S.L, Horne, W.S, Lengyel, G.A. 登録日 2023-06-01 公開日 2023-08-16 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability. Org.Biomol.Chem., 21, 2023
8T0I	Backbone Dialkylation in Peptide Hairpins: (R)-Ethylpropylglycine variant 分子名称: Immunoglobulin G-binding protein G 著者 Heath, S.L, Horne, W.S, Lengyel, G.A. 登録日 2023-06-01 公開日 2023-08-16 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Effects of chirality and side chain length in C alpha , alpha-dialkylated residues on beta-hairpin peptide folded structure and stability. Org.Biomol.Chem., 21, 2023
1S4A	NMR Structure of a D,L alternating decamer of norleucine: double antiparallel beta-helix 分子名称: HCO-(D-Nle-L-Nle)3-D-MeNle-L-Nle-D-Nle-L-Nle-OMe 著者 Navarro, E, Fenude, E, Celda, B. 登録日 2004-01-15 公開日 2004-02-24 最終更新日 2023-11-15 実験手法 SOLUTION NMR 主引用文献 Conformational and structural analysis of the equilibrium between single- and double-strand beta-helix of a D,L-alternating oligonorleucine. Biopolymers, 73, 2004
7OZ3	S. agalactiae BusR in complex with its busA-promotor DNA 分子名称: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, GntR family transcriptional regulator, pBusA_for, ... 著者 Bandera, A.M, Witte, G. 登録日 2021-06-25 公開日 2021-08-11 最終更新日 2024-07-17 実験手法 ELECTRON MICROSCOPY (4.46 Å) 主引用文献 BusR senses bipartite DNA binding motifs by a unique molecular ruler architecture. Nucleic Acids Res., 49, 2021
2N35	Fusion to a Highly Stable Consensus Albumin Binding Domain Allows for Tunable Pharmacokinetics 分子名称: Albumin binding protein 著者 Gibbs, A.C, Jacobs, S.A. 登録日 2015-05-21 公開日 2015-09-02 最終更新日 2024-05-15 実験手法 SOLUTION NMR 主引用文献 Fusion to a highly stable consensus albumin binding domain allows for tunable pharmacokinetics. Protein Eng.Des.Sel., 28, 2015
3J7X	Capsid Expansion Mechanism Of Bacteriophage T7 Revealed By Multi-State Atomic Models Derived From Cryo-EM Reconstructions 分子名称: Major capsid protein 10A 著者 Guo, F, Liu, Z, Fang, P.A, Zhang, Q, Wright, E.T, Wu, W, Zhang, C, Vago, F, Ren, Y, Jakata, J, Chiu, W, Serwer, P, Jiang, W. 登録日 2014-08-12 公開日 2014-10-15 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Capsid expansion mechanism of bacteriophage T7 revealed by multistate atomic models derived from cryo-EM reconstructions. Proc.Natl.Acad.Sci.USA, 111, 2014
1C30	CRYSTAL STRUCTURE OF CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTATION C269S 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... 著者 Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. 登録日 1999-07-24 公開日 1999-12-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999
1C3O	CRYSTAL STRUCTURE OF THE CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT MUTANT C269S WITH BOUND GLUTAMINE 分子名称: ADENOSINE-5'-DIPHOSPHATE, CARBAMOYL PHOSPHATE SYNTHETASE: LARGE SUBUNIT, CARBAMOYL PHOSPHATE SYNTHETASE: SMALL SUBUNIT, ... 著者 Thoden, J.B, Huang, X, Raushel, F.M, Holden, H.M. 登録日 1999-07-28 公開日 1999-12-10 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 The small subunit of carbamoyl phosphate synthetase: snapshots along the reaction pathway. Biochemistry, 38, 1999
4N2K	Crystal structure of Protein Arginine Deiminase 2 (Q350A, 0 mM Ca2+) 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, GLYCEROL, ... 著者 Slade, D.J, Zhang, X, Fang, P, Dreyton, C.J, Zhang, Y, Gross, M.L, Guo, M, Coonrod, S.A, Thompson, P.R. 登録日 2013-10-05 公開日 2015-02-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.57 Å) 主引用文献 Protein arginine deiminase 2 binds calcium in an ordered fashion: implications for inhibitor design. Acs Chem.Biol., 10, 2015
5MKF	cryoEM Structure of Polycystin-2 in complex with calcium and lipids 分子名称: 1,2-DIPALMITOYL-SN-GLYCERO-3-PHOSPHATE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Wilkes, M, Madej, M.G, Ziegler, C. 登録日 2016-12-04 公開日 2017-01-18 最終更新日 2020-07-29 実験手法 ELECTRON MICROSCOPY (4.2 Å) 主引用文献 Molecular insights into lipid-assisted Ca(2+) regulation of the TRP channel Polycystin-2. Nat. Struct. Mol. Biol., 24, 2017
4R1E	Crystal Structure of MTIP from Plasmodium falciparum in complex with a peptide-fragment chimera 分子名称: 5-{[(2-aminoethyl)sulfanyl]methyl}furan-2-carbaldehyde, Myosin A tail domain interacting protein, Myosin-A 著者 Douse, C.H, Vrielink, N, Cota, E, Tate, E.W. 登録日 2014-08-05 公開日 2014-11-12 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Targeting a Dynamic Protein-Protein Interaction: Fragment Screening against the Malaria Myosin A Motor Complex. Chemmedchem, 10, 2015
1CQ0	SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B'SOLUTION STRUCTURE OF A HUMAN HYPOCRETIN-2/OREXIN-B ' 分子名称: PROTEIN (NEW HYPOTHALAMIC NEUROPEPTIDE/OREXIN-B28) 著者 Lee, K.-H, Bang, E.J, Chae, K.-J, Lee, D.W, Lee, W. 登録日 1999-08-04 公開日 2000-01-10 最終更新日 2024-04-10 実験手法 SOLUTION NMR 主引用文献 Solution structure of a new hypothalamic neuropeptide, human hypocretin-2/orexin-B. Eur.J.Biochem., 266, 1999

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