8XCG
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8XC6
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8XBY
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![BU of 8xby by Molmil](/molmil-images/mine/8xby) | The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the blunt end of the nucleosome | 分子名称: | DNA (5'-D(P*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*CP*CP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*CP*GP*TP*T)-3'), DNA repair protein RAD51 homolog 1 | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-12-07 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.8 Å) | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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8XBX
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![BU of 8xbx by Molmil](/molmil-images/mine/8xbx) | The cryo-EM structure of the RAD51 L2 loop bound to the linker DNA with the blunt end of the nucleosome | 分子名称: | DNA (5'-D(P*AP*AP*CP*GP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*CP*CP*AP*CP*G)-3'), DNA (5'-D(P*CP*GP*TP*GP*GP*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*CP*GP*TP*T)-3'), DNA repair protein RAD51 homolog 1 | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-12-07 | 公開日 | 2024-03-27 | 最終更新日 | 2024-04-17 | 実験手法 | ELECTRON MICROSCOPY (4.36 Å) | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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8XBW
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![BU of 8xbw by Molmil](/molmil-images/mine/8xbw) | The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome | 分子名称: | DNA (5'-D(P*AP*CP*CP*GP*CP*TP*TP*AP*AP*AP*CP*GP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*CP*GP*TP*TP*TP*AP*AP*GP*CP*GP*GP*T)-3'), DNA repair protein RAD51 homolog 1, ... | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-12-07 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (2.89 Å) | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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8XBV
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![BU of 8xbv by Molmil](/molmil-images/mine/8xbv) | The cryo-EM structure of the RAD51 L1 and L2 loops bound to the linker DNA with the sticky end of the nucleosome | 分子名称: | DNA (5'-D(P*CP*GP*AP*AP*AP*AP*CP*GP*GP*CP*CP*AP*CP*CP*A)-3'), DNA (5'-D(P*TP*GP*GP*CP*CP*GP*TP*TP*TP*TP*CP*G)-3'), DNA repair protein RAD51 homolog 1 | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-12-07 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (7.61 Å) | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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8XBU
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![BU of 8xbu by Molmil](/molmil-images/mine/8xbu) | The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome with the linker DNA binding | 分子名称: | DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-12-07 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.24 Å) | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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8XBT
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![BU of 8xbt by Molmil](/molmil-images/mine/8xbt) | The cryo-EM structure of the octameric RAD51 ring bound to the nucleosome with the linker DNA binding | 分子名称: | DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ... | 著者 | Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2023-12-07 | 公開日 | 2024-03-27 | 最終更新日 | 2024-05-08 | 実験手法 | ELECTRON MICROSCOPY (4.12 Å) | 主引用文献 | Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site. Nature, 628, 2024
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8XBI
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![BU of 8xbi by Molmil](/molmil-images/mine/8xbi) | Human GPR34 -Gi complex bound to M1, receptor focused | 分子名称: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Probable G-protein coupled receptor 34 | 著者 | Kawahara, R, Shihoya, W, Nureki, O. | 登録日 | 2023-12-06 | 公開日 | 2023-12-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Structural basis for lysophosphatidylserine recognition by GPR34. Nat Commun, 15, 2024
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8XBH
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![BU of 8xbh by Molmil](/molmil-images/mine/8xbh) | Human GPR34 -Gi complex bound to M1 | 分子名称: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[3-[2-[(3-phenoxyphenyl)methoxy]phenyl]propanoyloxy]propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Kawahara, R, Shihoya, W, Nureki, O. | 登録日 | 2023-12-06 | 公開日 | 2023-12-27 | 最終更新日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (2.83 Å) | 主引用文献 | Structural basis for lysophosphatidylserine recognition by GPR34. Nat Commun, 15, 2024
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8XBG
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8XBF
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![BU of 8xbf by Molmil](/molmil-images/mine/8xbf) | Cryo-EM structure of SARS-CoV-2 S-BQ.1 in complex with antibody O5C2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, O5C2, heavy chain, ... | 著者 | Hsu, H.F, Wu, M.H, Chang, Y.C, Hsu, S.T.D. | 登録日 | 2023-12-06 | 公開日 | 2024-06-19 | 最終更新日 | 2024-06-26 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Functional and structural investigation of a broadly neutralizing SARS-CoV-2 antibody. JCI Insight, 9, 2024
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8XBE
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![BU of 8xbe by Molmil](/molmil-images/mine/8xbe) | Human GPR34 -Gi complex bound to S3E-LysoPS | 分子名称: | (2~{S})-2-azanyl-3-[[(2~{R})-1-ethoxy-3-[(~{Z})-octadec-9-enoyl]oxy-propan-2-yl]oxy-oxidanyl-phosphoryl]oxy-propanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Kawahara, R, Shihoya, W, Nureki, O. | 登録日 | 2023-12-06 | 公開日 | 2024-05-15 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structural basis for lysophosphatidylserine recognition by GPR34. Nat Commun, 15, 2024
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8XAR
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![BU of 8xar by Molmil](/molmil-images/mine/8xar) | Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with SAM and Compound 54 | 分子名称: | 1,2-ETHANEDIOL, 7-chloranyl-2-ethyl-5-pyridin-3-yl-pyrazolo[3,4-c]quinolin-4-one, CHLORIDE ION, ... | 著者 | Zheng, J.Y, Zhang, G.P, Li, J.J, Tong, S.L. | 登録日 | 2023-12-05 | 公開日 | 2024-06-26 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy. J.Med.Chem., 67, 2024
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8XAJ
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8XAB
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8X93
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![BU of 8x93 by Molmil](/molmil-images/mine/8x93) | P/Q type calcium channel in complex with omega-Agatoxin IVA | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Li, Z, Cong, Y, Wu, T, Wang, T. | 登録日 | 2023-11-29 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.92 Å) | 主引用文献 | Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell Res., 34, 2024
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8X91
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![BU of 8x91 by Molmil](/molmil-images/mine/8x91) | P/Q type calcium channel in complex with omega-conotoxin MVIIC | 分子名称: | 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Li, Z, Cong, Y, Wu, T, Wang, T. | 登録日 | 2023-11-29 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (3.11 Å) | 主引用文献 | Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell Res., 34, 2024
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8X90
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![BU of 8x90 by Molmil](/molmil-images/mine/8x90) | P/Q type calcium channel | 分子名称: | 1,2-DIDECANOYL-SN-GLYCERO-3-[PHOSPHO-L-SERINE], 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Yan, N, Li, Z, Cong, Y, Wu, T, Wang, T. | 登録日 | 2023-11-29 | 公開日 | 2024-03-20 | 最終更新日 | 2024-06-19 | 実験手法 | ELECTRON MICROSCOPY (2.95 Å) | 主引用文献 | Structural basis for different omega-agatoxin IVA sensitivities of the P-type and Q-type Ca v 2.1 channels. Cell Res., 34, 2024
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8X8V
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![BU of 8x8v by Molmil](/molmil-images/mine/8x8v) | Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment | 分子名称: | Polyhedrin,Myc proto-oncogene protein | 著者 | Kojima, M, Ueno, T, Abe, S, Hirata, K. | 登録日 | 2023-11-29 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
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8X8S
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![BU of 8x8s by Molmil](/molmil-images/mine/8x8s) | Crystal structure of Cypovirus Polyhedra mutant fused with c-Myc fragment | 分子名称: | Polyhedrin,Myc proto-oncogene protein | 著者 | Kojima, M, Ueno, T, Abe, S, Hirata, K. | 登録日 | 2023-11-28 | 公開日 | 2024-06-05 | 最終更新日 | 2024-07-03 | 実験手法 | X-RAY DIFFRACTION (2.04 Å) | 主引用文献 | High-throughput structure determination of an intrinsically disordered protein using cell-free protein crystallization. Proc.Natl.Acad.Sci.USA, 121, 2024
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8X7Z
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![BU of 8x7z by Molmil](/molmil-images/mine/8x7z) | |
8X7X
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8X79
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![BU of 8x79 by Molmil](/molmil-images/mine/8x79) | MRE-269 bound Prostacyclin Receptor G protein complex | 分子名称: | 2-[4-[(5,6-diphenylpyrazin-2-yl)-propan-2-yl-amino]butoxy]ethanoic acid, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | 著者 | Wang, J.J, Jin, S, Zhang, H, Xu, Y, Hu, W, Jiang, Y, Chen, C, Wang, D.W, Xu, H.E, Wu, C. | 登録日 | 2023-11-23 | 公開日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (2.41 Å) | 主引用文献 | Molecular recognition and activation of the prostacyclin receptor by anti-pulmonary arterial hypertension drugs. Sci Adv, 10, 2024
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8X77
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![BU of 8x77 by Molmil](/molmil-images/mine/8x77) | Enterovirus proteinase with host factor | 分子名称: | 2A protein, Actin-histidine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE, ... | 著者 | Gao, X, Cui, S. | 登録日 | 2023-11-23 | 公開日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.52 Å) | 主引用文献 | The EV71 2A protease occupies the central cleft of SETD3 and disrupts SETD3-actin interaction. Nat Commun, 15, 2024
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