2XYV
| Crystal structure of the nsp16 nsp10 SARS coronavirus complex | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ... | 著者 | Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B. | 登録日 | 2010-11-19 | 公開日 | 2011-10-26 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.06 Å) | 主引用文献 | Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7, 2011
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2XYQ
| Crystal structure of the nsp16 nsp10 SARS coronavirus complex | 分子名称: | CHLORIDE ION, MAGNESIUM ION, NON-STRUCTURAL PROTEIN 10, ... | 著者 | Decroly, E, Debarnot, C, Ferron, F, Bouvet, M, Coutard, B, Imbert, I, Gluais, L, Papageorgiou, N, Ortiz-Lombardia, M, Lescar, J, Canard, B. | 登録日 | 2010-11-18 | 公開日 | 2011-10-19 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure and Functional Analysis of the Sars-Coronavirus RNA CAP 2'-O-Methyltransferase Nsp10/Nsp16 Complex. Plos Pathog., 7, 2011
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2ZU4
| Complex structure of SARS-CoV 3CL protease with TG-0204998 | 分子名称: | 3C-like proteinase, N-[(benzyloxy)carbonyl]-3-[(2,2-dimethylpropanoyl)amino]-L-alanyl-N-[(1R)-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}pentyl]-L-leucinamide | 著者 | Hsu, M.F, Lee, C.C, Wang, A.H.-J. | 登録日 | 2008-10-12 | 公開日 | 2009-01-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds J.Biol.Chem., 284, 2009
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2ZTX
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2ZU5
| complex structure of SARS-CoV 3CL protease with TG-0205486 | 分子名称: | 3C-like proteinase, N-[(benzyloxy)carbonyl]-O-tert-butyl-L-threonyl-N-[(1R)-4-cyclopropyl-4-oxo-1-{[(3S)-2-oxopyrrolidin-3-yl]methyl}butyl]-L-leucinamide | 著者 | Hsu, M.F, Lee, C.C, Wang, A.H.-J. | 登録日 | 2008-10-12 | 公開日 | 2009-01-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds J.Biol.Chem., 284, 2009
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2ZU1
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2A5I
| Crystal structures of SARS coronavirus main peptidase inhibited by an aza-peptide epoxide in the space group C2 | 分子名称: | (5S,8S,14R)-ETHYL 11-(3-AMINO-3-OXOPROPYL)-8-BENZYL-14-HYDROXY-5-ISOBUTYL-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,11-TETRAAZAPENTADECAN-15-OATE, 1,2-ETHANEDIOL, 3C-like peptidase, ... | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C, Eltis, L.D, James, M.N. | 登録日 | 2005-06-30 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | 主引用文献 | Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide J.Mol.Biol., 353, 2005
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2CBY
| Crystal structure of the ATP-dependent Clp Protease proteolytic subunit 1 (ClpP1) from Mycobacterium tuberculosis | 分子名称: | ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 | 著者 | Mate, M.J, Portnoi, D, Alzari, P.M, Ortiz-Lombardia, M. | 登録日 | 2006-01-10 | 公開日 | 2006-01-11 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1. Acta Crystallogr.,Sect.D, 63, 2007
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2ZU2
| complex structure of CoV 229E 3CL protease with EPDTC | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 3C-like proteinase, zinc(II)hydrogensulfide | 著者 | Lee, C.C, Wang, A.H.-J. | 登録日 | 2008-10-12 | 公開日 | 2009-01-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis of Inhibition Specificities of 3C and 3C-like Proteases by Zinc-coordinating and Peptidomimetic Compounds J.Biol.Chem., 284, 2009
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2ZTY
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2ZTZ
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2Z3C
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2Z3D
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2Z3E
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3AW0
| Structure of SARS 3CL protease with peptidic aldehyde inhibitor | 分子名称: | 3C-Like Proteinase, peptide ACE-SER-ALA-VAL-LEU-HIS-H | 著者 | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | 登録日 | 2011-03-09 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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3AW1
| Structure of SARS 3CL protease auto-proteolysis resistant mutant in the absent of inhibitor | 分子名称: | 3C-Like Proteinase | 著者 | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | 登録日 | 2011-03-09 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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2B9L
| Crystal structure of prophenoloxidase activating factor-II from the beetle Holotrichia diomphalia | 分子名称: | CALCIUM ION, SULFATE ION, alpha-L-fucopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)][alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Piao, S, Song, Y.-L, Park, S.Y, Lee, B.L, Oh, B.-H, Ha, N.-C. | 登録日 | 2005-10-12 | 公開日 | 2006-01-03 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of a clip-domain serine protease and functional roles of the clip domains. Embo J., 24, 2005
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3ATW
| Structure-Based Design, Synthesis, Evaluation of Peptide-mimetic SARS 3CL Protease Inhibitors | 分子名称: | 3C-Like Proteinase, peptide ACE-THR-VAL-ALC-HIS-H | 著者 | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | 登録日 | 2011-01-20 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.36 Å) | 主引用文献 | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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3AVZ
| Structure of SARS 3CL protease with peptidic aldehyde inhibitor containing cyclohexyl side chain | 分子名称: | 3C-Like Proteinase, peptide ACE-SER-ALA-VAL-ALC-HIS-H | 著者 | Akaji, K, Konno, H, Mitsui, H, Teruya, K, Hattori, Y, Ozaki, T, Kusunoki, M, Sanjho, A. | 登録日 | 2011-03-09 | 公開日 | 2011-12-14 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.46 Å) | 主引用文献 | Structure-Based Design, Synthesis, and Evaluation of Peptide-Mimetic SARS 3CL Protease Inhibitors. J.Med.Chem., 54, 2011
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2A5K
| Crystal structures of SARS coronavirus main peptidase inhibited by an aza-peptide epoxide in space group P212121 | 分子名称: | (5S,8S,14R)-ETHYL 11-(3-AMINO-3-OXOPROPYL)-8-BENZYL-14-HYDROXY-5-ISOBUTYL-3,6,9,12-TETRAOXO-1-PHENYL-2-OXA-4,7,10,11-TETRAAZAPENTADECAN-15-OATE, 3C-like peptidase | 著者 | Lee, T.-W, Cherney, M.M, Huitema, C, Liu, J, James, K.E, Powers, J.C, Eltis, L.D, James, M.N. | 登録日 | 2005-06-30 | 公開日 | 2005-10-25 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of the Main Peptidase from the SARS Coronavirus Inhibited by a Substrate-like Aza-peptide Epoxide J.Mol.Biol., 353, 2005
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1MTP
| The X-ray crystal structure of a serpin from a thermophilic prokaryote | 分子名称: | Serine Proteinase Inhibitor (SERPIN), Chain A, Chain B | 著者 | Irving, J.A, Cabrita, L.D, Rossjohn, J, Pike, R.N, Bottomley, S.P, Whisstock, J.C. | 登録日 | 2002-09-21 | 公開日 | 2003-04-15 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment Structure, 11, 2003
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1L1J
| Crystal structure of the protease domain of an ATP-independent heat shock protease HtrA | 分子名称: | heat shock protease HtrA | 著者 | Kim, D.Y, Kim, D.R, Ha, S.C, Lokanath, N.K, Hwang, H.Y, Kim, K.K. | 登録日 | 2002-02-18 | 公開日 | 2003-04-01 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal Structure of the Protease Domain of a Heat-shock Protein HtrA from Thermotoga maritima J.BIOL.CHEM., 278, 2003
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1LVB
| CATALYTICALLY INACTIVE TOBACCO ETCH VIRUS PROTEASE COMPLEXED WITH SUBSTRATE | 分子名称: | CATALYTIC DOMAIN OF THE NUCLEAR INCLUSION PROTEIN A (NIA), GLYCEROL, OLIGOPEPTIDE SUBSTRATE FOR THE PROTEASE | 著者 | Phan, J, Zdanov, A, Evdokimov, A.G, Tropea, J.E, Peters III, H.K, Kapust, R.B, Li, M, Wlodawer, A, Waugh, D.S. | 登録日 | 2002-05-28 | 公開日 | 2002-11-27 | 最終更新日 | 2021-10-27 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Structural basis for the substrate specificity of tobacco etch virus protease. J.Biol.Chem., 277, 2002
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1MXO
| AmpC beta-lactamase in complex with an m.carboxyphenylglycylboronic acid bearing the cephalothin R1 side chain | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-(3-CARBOXYPHENYL)METHYLBORONIC ACID, Beta-lactamase, PHOSPHATE ION | 著者 | Morandi, F, Caselli, E, Morandi, S, Focia, P.J, Blazquez, J, Shoichet, B.K, Prati, F. | 登録日 | 2002-10-02 | 公開日 | 2003-03-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | 主引用文献 | Nanomolar inhibitors of AmpC beta-lactamase. J.Am.Chem.Soc., 125, 2003
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1MY8
| AmpC beta-lactamase in complex with an M.carboxyphenylglycylboronic acid bearing the cephalothin R1 side chain | 分子名称: | (1R)-1-(2-THIENYLACETYLAMINO)-1-PHENYLMETHYLBORONIC ACID, PHOSPHATE ION, beta-lactamase | 著者 | Morandi, F, Caselli, E, Morandi, S, Focia, P.J, Blazquez, J, Shoichet, B.K, Prati, F. | 登録日 | 2002-10-03 | 公開日 | 2003-03-04 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.72 Å) | 主引用文献 | Nanomolar inhibitors of AmpC beta-lactamase. J.Am.Chem.Soc., 125, 2003
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