2Z3D

A Mechanistic view of Enzyme Inhibition and Peptide Hydrolysis in the Active Site of the SARS-CoV 3C-Like peptidase

Summary for 2Z3D

• Entry DOI: 10.2210/pdb2z3d/pdb
• Related: 2Z3C
• Related PRD ID: PRD_000235
• Descriptor: Replicase polyprotein 1ab (pp1ab), Inhibitor, GLYCEROL, ... (4 entities in total)
• Functional Keywords: beta barrels, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
• Biological source: SARS coronavirus (SARS-CoV); More
• Total number of polymer chains: 2
• Total formula weight: 34422.31

Authors

Yin, J. (deposition date: 2007-06-04, release date: 2007-07-03, Last modification date: 2023-11-15)

• Primary citation: Yin, J.,Niu, C.,Cherney, M.M.,Zhang, J.,Huitema, C.,Eltis, L.D.,Vederas, J.C.,James, M.N.; A mechanistic view of enzyme inhibition and peptide hydrolysis in the active site of the SARS-CoV 3C-like peptidase; J.Mol.Biol., 371:1060-1074, 2007; PubMed: 17599357; DOI: 10.1016/j.jmb.2007.06.001

Experimental method

X-RAY DIFFRACTION (2.1 Å)