2HKH
 
 | | Crystal structure of the Fab M75 | | 分子名称: | GLYCEROL, Immunoglobulin Heavy chain Fab fragment, Immunoglobulin Light chain Fab fragment | | 著者 | Kral, V, Mader, P, Stouracova, R, Fabry, M, Sedlacek, J, Brynda, J. | | 登録日 | 2006-07-04 | | 公開日 | 2007-11-13 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Stabilization of antibody structure upon association to a human carbonic anhydrase IX epitope studied by X-ray crystallography, microcalorimetry, and molecular dynamics simulations.
Proteins, 71, 2008
|
|
2HKF
 | | Crystal structure of the Complex Fab M75- Peptide | | 分子名称: | Carbonic anhydrase 9, Immunoglobulin Heavy chain Fab fragment, Immunoglobulin Light chain Fab fragment | | 著者 | Kral, V, Mader, P, Stouracova, R, Fabry, M, Horejsi, M, Brynda, J. | | 登録日 | 2006-07-04 | | 公開日 | 2007-11-13 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | | 主引用文献 | Stabilization of antibody structure upon association to a human carbonic anhydrase IX epitope studied by X-ray crystallography, microcalorimetry, and molecular dynamics simulations.
Proteins, 71, 2008
|
|
6MU3
 | | Anti-HIV-1 Fab 2G12 + Man7 re-refinement | | 分子名称: | Fab 2G12, heavy chain, light chain, ... | | 著者 | Wilson, I.A, Calarese, D.A, Stanfield, R.L. | | 登録日 | 2018-10-22 | | 公開日 | 2018-10-31 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.327 Å) | | 主引用文献 | Dissection of the carbohydrate specificity of the broadly neutralizing anti-HIV-1 antibody 2G12.
Proc. Natl. Acad. Sci. U.S.A., 102, 2005
|
|
6N41
 | |
1YNT
 | | Structure of the monomeric form of T. gondii SAG1 surface antigen bound to a human Fab | | 分子名称: | 4F11E12 Fab variable heavy chain region, 4F11E12 Fab variable light chain region, CADMIUM ION, ... | | 著者 | Graille, M, Stura, E.A, Bossus, M, Muller, B.H, Letourneur, O, Battail-Poirot, N, Sibai, G, Rolland, D, Le Du, M.H, Ducancel, F. | | 登録日 | 2005-01-25 | | 公開日 | 2005-12-27 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Crystal structure of the complex between the monomeric form of Toxoplasma gondii surface antigen 1 (SAG1) and a monoclonal antibody that mimics the human immune response
J.Mol.Biol., 354, 2005
|
|
1LO0
 | | Catalytic Retro-Diels-Alderase Transition State Analogue Complex | | 分子名称: | 3-{[(9-CYANO-9,10-DIHYDRO-10-METHYLACRIDIN-9-YL)CARBONYL]AMINO}PROPANOIC ACID, If kappa light chain, Ig gamma 2a heavy chain | | 著者 | Hugot, M, Reymond, J.L, Baumann, U. | | 登録日 | 2002-05-05 | | 公開日 | 2002-06-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A structural basis for the activity of retro-Diels-Alder catalytic antibodies: evidence for a catalytic aromatic residue.
Proc.Natl.Acad.Sci.USA, 99, 2002
|
|
8G9X
 | | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 2) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | 著者 | Changela, A, Gorman, J, Kwong, P.D. | | 登録日 | 2023-02-22 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (4.46 Å) | | 主引用文献 | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
|
|
2A1W
 | | Anti-cocaine antibody 7.5.21, crystal form I | | 分子名称: | SULFATE ION, immunoglobulin heavy chain, immunoglobulin light chain kappa | | 著者 | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | | 登録日 | 2005-06-21 | | 公開日 | 2005-06-28 | | 最終更新日 | 2017-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Flexibility Of Packing:
Four Crystal Forms Of An Anti-Cocaine Antibody 7.5.21
To be Published
|
|
6ONA
 | |
2A77
 | | Anti-Cocaine Antibody 7.5.21, Crystal Form II | | 分子名称: | GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain, ... | | 著者 | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | | 登録日 | 2005-07-04 | | 公開日 | 2005-07-12 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21
To be Published
|
|
6UQR
 | | Complex of IgE and Ligelizumab | | 分子名称: | IgE, Ligelizumab, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Tarchevskaya, S.S, Kleinboelting, S, Jardetzky, T.S. | | 登録日 | 2019-10-21 | | 公開日 | 2019-12-04 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (3.6502912 Å) | | 主引用文献 | The mechanistic and functional profile of the therapeutic anti-IgE antibody ligelizumab differs from omalizumab.
Nat Commun, 11, 2020
|
|
1YEG
 | | STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH REACTION PRODUCT | | 分子名称: | ACETATE ION, IGG2A FAB FRAGMENT, PARANITROBENZYL ALCOHOL, ... | | 著者 | Gigant, B, Knossow, M. | | 登録日 | 1997-05-29 | | 公開日 | 1997-12-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
|
|
6OSR
 | |
4PTT
 | | Crystal Structure of anti-23F strep Fab C05 | | 分子名称: | ACETATE ION, Antibody pn132p2C05, heavy chain, ... | | 著者 | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Smith, K, Schrader, J.W, Pai, E.F. | | 登録日 | 2014-03-11 | | 公開日 | 2015-03-11 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.
J. Immunol., 196, 2016
|
|
8G9W
 | | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 1) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | 著者 | Changela, A, Gorman, J, Kwong, P.D. | | 登録日 | 2023-02-22 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (4.66 Å) | | 主引用文献 | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
|
|
8G9Y
 | | Cryo-EM structure of vFP49.02 Fab in complex with HIV-1 Env BG505 DS-SOSIP.664 (conformation 3) | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ... | | 著者 | Changela, A, Gorman, J, Kwong, P.D. | | 登録日 | 2023-02-22 | | 公開日 | 2023-04-19 | | 最終更新日 | 2023-06-14 | | 実験手法 | ELECTRON MICROSCOPY (4.28 Å) | | 主引用文献 | Diverse Murine Vaccinations Reveal Distinct Antibody Classes to Target Fusion Peptide and Variation in Peptide Length to Improve HIV Neutralization.
J.Virol., 97, 2023
|
|
5HDQ
 | | MntC co-structure with mAB 305-78-7 | | 分子名称: | ABC transporter substrate-binding protein, FE (III) ION, Fab Heavy Chain, ... | | 著者 | Parris, K, Mosyak, L. | | 登録日 | 2016-01-05 | | 公開日 | 2016-09-21 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.83 Å) | | 主引用文献 | High Resolution Mapping of Bactericidal Monoclonal Antibody Binding Epitopes on Staphylococcus aureus Antigen MntC.
Plos Pathog., 12, 2016
|
|
2BJM
 | | SPE7:Anthrone Complex | | 分子名称: | ANTHRONE, IGE SPE7 HEAVY CHAIN, IGE SPE7 LIGHT CHAIN | | 著者 | James, L.C, Tawfik, D.S. | | 登録日 | 2005-02-04 | | 公開日 | 2005-08-18 | | 最終更新日 | 2013-10-30 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structure and Kinetics of a Transient Antibody Binding Intermediate Reveal a Kinetic Discrimination Mechanism in Antigen Recognition
Proc.Natl.Acad.Sci.USA, 102, 2005
|
|
2AI0
 | | Anti-Cocaine Antibody 7.5.21, Crystal Form III | | 分子名称: | GLYCEROL, Immunoglobulin Heavy Chain, Immunoglobulin Light Chain kappa, ... | | 著者 | Pozharski, E, Hewagama, A, Shanafelt, A, Ringe, D, Petsko, G.A. | | 登録日 | 2005-07-28 | | 公開日 | 2005-08-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Flexibility of Packing: Four Crystal Forms of an Anti-Cocaine Antibody 7.5.21
To be Published
|
|
6MH2
 | | Structure of Herceptin Fab without antigen | | 分子名称: | Herceptin Fab arm heavy chain, Herceptin Fab arm light chain | | 著者 | Luthra, A, Langley, D.B, Christie, M, Christ, D. | | 登録日 | 2018-09-17 | | 公開日 | 2019-05-29 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Human Antibody Bispecifics through Phage Display Selection.
Biochemistry, 58, 2019
|
|
4DVA
 | | The crystal structure of human urokinase-type plasminogen activator catalytic domain | | 分子名称: | HEXAETHYLENE GLYCOL, SULFATE ION, Urokinase-type plasminogen activator | | 著者 | Jiang, L, Botkjaer, K.A, Andersen, L.M, Yuan, C, Andreasen, P.A, Huang, M. | | 登録日 | 2012-02-23 | | 公開日 | 2013-01-16 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Rezymogenation of active urokinase induced by an inhibitory antibody
Biochem.J., 449, 2013
|
|
1YEF
 | | STRUCTURE OF IGG2A FAB FRAGMENT (D2.3) COMPLEXED WITH SUBSTRATE ANALOGUE | | 分子名称: | IGG2A FAB FRAGMENT, PARA-NITROBENZYL GLUTARYL GLYCINIC ACID, ZINC ION | | 著者 | Gigant, B, Knossow, M. | | 登録日 | 1997-05-29 | | 公開日 | 1997-12-03 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | X-ray structures of a hydrolytic antibody and of complexes elucidate catalytic pathway from substrate binding and transition state stabilization through water attack and product release.
Proc.Natl.Acad.Sci.USA, 94, 1997
|
|
4PTU
 | | Crystal Structure of anti-23F strep Fab C05 with rhamnose | | 分子名称: | ACETATE ION, Antibody pn132p2C05, heavy chain, ... | | 著者 | Bryson, S, Risnes, L, Damgupta, S, Thomson, C.A, Smith, K, Schrader, J.W, Pai, E.F. | | 登録日 | 2014-03-11 | | 公開日 | 2015-03-04 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.511 Å) | | 主引用文献 | Structures of Preferred Human IgV Genes-Based Protective Antibodies Identify How Conserved Residues Contact Diverse Antigens and Assign Source of Specificity to CDR3 Loop Variation.
J. Immunol., 196, 2016
|
|
6VO3
 | | AMC009 SOSIP.v4.2 in complex with PGV04 Fab | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, AMC009 SOSIP.v4.2 envelope glycoprotein gp120, ... | | 著者 | Cottrell, C.A, de Val, N, Ward, A.B. | | 登録日 | 2020-01-29 | | 公開日 | 2020-09-23 | | 最終更新日 | 2020-12-09 | | 実験手法 | ELECTRON MICROSCOPY (4.25 Å) | | 主引用文献 | Neutralizing Antibody Responses Induced by HIV-1 Envelope Glycoprotein SOSIP Trimers Derived from Elite Neutralizers.
J.Virol., 94, 2020
|
|
12E8
 | | 2E8 FAB FRAGMENT | | 分子名称: | IGG1-KAPPA 2E8 FAB (HEAVY CHAIN), IGG1-KAPPA 2E8 FAB (LIGHT CHAIN) | | 著者 | Rupp, B, Trakhanov, S. | | 登録日 | 1998-03-14 | | 公開日 | 1998-08-05 | | 最終更新日 | 2023-08-02 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structure of a monoclonal 2E8 Fab antibody fragment specific for the low-density lipoprotein-receptor binding region of apolipoprotein E refined at 1.9 A.
Acta Crystallogr.,Sect.D, null, 1999
|
|
