PDB: 6545 件ウェブページステータス検索Chemie searchBIRD

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5DEC	Crystal structure of the small alarmone synthetase 1 from Bacillus subtilis 分子名称: GTP pyrophosphokinase YjbM 著者 Steinchen, W, Altegoer, A, Schuhmacher, J.S, Bange, G. 登録日 2015-08-25 公開日 2015-10-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Catalytic mechanism and allosteric regulation of an oligomeric (p)ppGpp synthetase by an alarmone. Proc.Natl.Acad.Sci.USA, 112, 2015
5DGS	Crystal structure of human FPPS in complex with the monophosphonate compound 15 分子名称: Farnesyl pyrophosphate synthase, {(E)-2-[6-(acetylamino)-8-(naphthalen-1-yl)quinolin-2-yl]ethenyl}phosphonic acid 著者 Rondeau, J.M, Bourgier, E, Lehmann, S. 登録日 2015-08-28 公開日 2016-07-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 A General Strategy for Targeting Drugs to Bone. Angew.Chem.Int.Ed.Engl., 54, 2015
8G7F	Crystal Structure of FosB from Bacillus cereus with Zinc and 1-hydroxypropylphosphonic acid 分子名称: FORMIC ACID, GLYCEROL, MAGNESIUM ION, ... 著者 Travis, S, Pang, A.H, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. 登録日 2023-02-16 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.04 Å) 主引用文献 Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
8G7G	Crystal Structure of FosB from Bacillus cereus with Zinc and (1-hydroxy-2-methylpropyl)phosphonic acid 分子名称: FORMIC ACID, MAGNESIUM ION, Metallothiol transferase FosB, ... 著者 Travis, S, Pang, A.H, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. 登録日 2023-02-16 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
8GN0	Crystal structure of DCBQ-bound photosystem II complex 分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Kamada, S, Nakajima, Y, Shen, J.-R. 登録日 2022-08-22 公開日 2023-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Structural insights into the action mechanisms of artificial electron acceptors in photosystem II. J.Biol.Chem., 299, 2023
8GN2	Crystal structure of PPBQ-bound photosystem II complex 分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Kamada, S, Nakajima, Y, Shen, J.-R. 登録日 2022-08-22 公開日 2023-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural insights into the action mechanisms of artificial electron acceptors in photosystem II. J.Biol.Chem., 299, 2023
8G3F	BceAB-S nucleotide free BceS state 1 分子名称: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... 著者 George, N.L, Orlando, B.J. 登録日 2023-02-07 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.7 Å) 主引用文献 Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
8G7H	Crystal Structure of FosB from Bacillus cereus with Zinc and (1-hydroxypropan-2-yl)phosphonic acid 分子名称: FORMIC ACID, GLYCEROL, MAGNESIUM ION, ... 著者 Travis, S, Pang, A.H, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. 登録日 2023-02-16 公開日 2023-06-14 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.81 Å) 主引用文献 Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
8G7I	Crystal Structure of FosB from Bacillus cereus with Zinc and Sulfate 分子名称: FORMIC ACID, GLYCEROL, MAGNESIUM ION, ... 著者 Travis, S, Pang, A.H, Tsodikov, O.V, Garneau-Tsodikova, S, Thompson, M.K. 登録日 2023-02-16 公開日 2023-06-14 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Identification and analysis of small molecule inhibitors of FosB from Staphylococcus aureus. Rsc Med Chem, 14, 2023
8G3B	BceAB-S nucleotide free TM state 2 分子名称: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... 著者 George, N.L, Orlando, B.J. 登録日 2023-02-07 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
6SDQ	Trypanosoma cruzi farnesyl diphosphate synthase in complex with fragment 2m5n 分子名称: 2-methoxy-5-nitro-phenol, Farnesyl diphosphate synthase, SULFATE ION, ... 著者 Magari, F, Heine, A, Klebe, G. 登録日 2019-07-29 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Trypanosoma cruzi farnesyl diphosphate synthase in complex with fragment 2m5n To Be Published
8GN1	Crystal structure of DBBQ-bound photosystem II complex 分子名称: (3R)-beta,beta-caroten-3-ol, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Kamada, S, Nakajima, Y, Shen, J.-R. 登録日 2022-08-22 公開日 2023-07-05 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights into the action mechanisms of artificial electron acceptors in photosystem II. J.Biol.Chem., 299, 2023
8G3L	BceAB-S nucleotide free BceS state 2 分子名称: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... 著者 George, N.L, Orlando, B.J. 登録日 2023-02-08 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
6SI5	T. cruzi FPPS in complex with 1-methyl-5-(4,5,6,7-tetrahydrothieno[3,2-c]pyridine-5-carbonyl)pyridin-2(1H)-one 分子名称: 5-(6,7-dihydro-4~{H}-thieno[3,2-c]pyridin-5-ylcarbonyl)-1-methyl-pyridin-2-one, Farnesyl diphosphate synthase, SULFATE ION 著者 Petrick, J.K, Muenzker, L, Schleberger, C, Cornaciu, I, Clavel, D, Marquez, J.A, Jahnke, W. 登録日 2019-08-08 公開日 2020-08-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.097 Å) 主引用文献 Targeting farnesyl pyrophosphate synthase of Trypanosoma cruzi by fragment-based lead discovery Thesis, 2019
6SII	T. brucei FPPS in complex with 1-((1H-indol-3-yl)methyl)-N-(3-chlorobenzyl)piperidin-4-amine 分子名称: Farnesyl pyrophosphate synthase, GLYCEROL, ~{N}-[(3-chlorophenyl)methyl]-1-(1~{H}-indol-3-ylmethyl)piperidin-4-amine 著者 Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W. 登録日 2019-08-09 公開日 2020-08-26 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 T. brucei FPPS To Be Published
8ECM	Crystal Structure Analysis of Acetyl-CoA acetyltransferase from Firmicutes bacterium 分子名称: Acetyl-CoA acetyltransferase 著者 Seo, H.S, Dhe-Paganon, S. 登録日 2022-09-02 公開日 2023-05-31 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease. Nat Med, 29, 2023
8G4C	BceABS ATPgS high res TM 分子名称: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 George, N.L, Orlando, B.J. 登録日 2023-02-09 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
5AEL	T. Brucei Farnesyl Diphosphate Synthase Complexed with Bisphosphonate BPH-597 分子名称: FARNESYL PYROPHOSPHATE SYNTHASE, MAGNESIUM ION, {2-[3-(hex-1-yn-1-yl)pyridinium-1-yl]ethane-1,1-diyl}bis(phosphonate) 著者 Yang, G, Oldfield, E, No, J.H. 登録日 2014-12-26 公開日 2015-10-28 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Inhibition of Trypanosoma Brucei Cell Growth by Lipophilic Bisphosphonates: An in Vitro and in Vivo Investigation. Antimicrob.Agents Chemother., 59, 2015
8G4D	BceABS ATPgS tilted BceS 分子名称: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER, ... 著者 George, N.L, Orlando, B.J. 登録日 2023-02-09 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
8G3A	BceAB-S nucleotide free TM state 1 分子名称: Bacitracin export ATP-binding protein BceA, Bacitracin export permease protein BceB, OLEIC ACID, ... 著者 George, N.L, Orlando, B.J. 登録日 2023-02-07 公開日 2023-06-21 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.4 Å) 主引用文献 Architecture of a complete Bce-type antimicrobial peptide resistance module. Nat Commun, 14, 2023
6SWJ	The kinase domain of GanS, a histidine kinase from Geobacillus stearothermophilus (with Pt) 分子名称: Histidine kinase, PLATINUM (II) ION 著者 Lansky, S, Shiradski, M, Lavid, N, Shoham, Y, Shoham, G. 登録日 2019-09-22 公開日 2020-10-14 最終更新日 2024-05-15 実験手法 X-RAY DIFFRACTION (1.762 Å) 主引用文献 The kinase domain of GanS, a histidine kinase from Geobacillus stearothermophilus (with Pt) To Be Published
6SX4	Structure of C. glutamicum mycoloyltransferase A 分子名称: ACETATE ION, Protein PS1 著者 Li de la Sierra-Gallay, I, Van tilbeurgh, H, Bayan, N. 登録日 2019-09-24 公開日 2020-03-04 最終更新日 2020-07-22 実験手法 X-RAY DIFFRACTION (2.796 Å) 主引用文献 The C-terminal domain of Corynebacterium glutamicum mycoloyltransferase A is composed of five repeated motifs involved in cell wall binding and stability. Mol.Microbiol., 114, 2020
6SZG	Acinetobacter baumannii undecaprenyl pyrophosphate synthase (AB-UppS) in complex with GR839 and GSK513 分子名称: (4-chlorophenyl)-[(3~{S})-3-oxidanylpiperidin-1-yl]methanone, 4,5,6,7-tetrahydro-2~{H}-indazole-3-carboxylic acid, CALCIUM ION, ... 著者 Thorpe, J.H. 登録日 2019-10-02 公開日 2020-01-22 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Cocktailed fragment screening by X-ray crystallography of the antibacterial target undecaprenyl pyrophosphate synthase from Acinetobacter baumannii. Acta Crystallogr.,Sect.F, 76, 2020
6R38	T. brucei FPPS in complex with 2-(2,5-dichlorobenzo[b]thiophen-3-yl)acetic acid 分子名称: 2-[2,5-bis(chloranyl)-1-benzothiophen-3-yl]ethanoic acid, DIMETHYL SULFOXIDE, Farnesyl pyrophosphate synthase 著者 Muenzker, L, Petrick, J.K, Schleberger, C, Jahnke, W. 登録日 2019-03-19 公開日 2020-04-08 最終更新日 2024-01-24 実験手法 X-RAY DIFFRACTION (2.33 Å) 主引用文献 Targeting Trypanosoma brucei FPPS by Fragment-based drug discovery Thesis, 2019
5AB7	Crystal structure of Trypanosoma brucei SCP2-thiolase like protein (TbSLP) in complex with malonyl-CoA. 分子名称: MALONYL-COENZYME A, SCP2-THIOLASE LIKE PROTEIN, SULFATE ION 著者 Harijan, R.K, Kiema, T.R, Wierenga, R.K. 登録日 2015-08-02 公開日 2016-05-04 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 The Scp2-Thiolase-Like Protein (Slp) of Trypanosoma Brucei is an Enzyme Involved in Lipid Metabolism. Proteins, 84, 2016

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