6SZG

Acinetobacter baumannii undecaprenyl pyrophosphate synthase (AB-UppS) in complex with GR839 and GSK513

Summary for 6SZG

Entry DOI	10.2210/pdb6szg/pdb
Descriptor	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific), 4,5,6,7-tetrahydro-2~{H}-indazole-3-carboxylic acid, (4-chlorophenyl)-[(3~{S})-3-oxidanylpiperidin-1-yl]methanone, ... (5 entities in total)
Functional Keywords	inhibitor complex, transferase
Biological source	Acinetobacter baumannii
Total number of polymer chains	2
Total formula weight	62255.70
Authors	Thorpe, J.H. (deposition date: 2019-10-02, release date: 2020-01-22, Last modification date: 2024-01-24)
Primary citation	Thorpe, J.H.,Wall, I.D.,Sinnamon, R.H.,Taylor, A.N.,Stavenger, R.A. Cocktailed fragment screening by X-ray crystallography of the antibacterial target undecaprenyl pyrophosphate synthase from Acinetobacter baumannii. Acta Crystallogr.,Sect.F, 76:40-46, 2020 Cited by PubMed: 31929185 DOI: 10.1107/S2053230X19017199 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.84 Å)

Structure validation