6SZG

Acinetobacter baumannii undecaprenyl pyrophosphate synthase (AB-UppS) in complex with GR839 and GSK513

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000287	molecular_function	magnesium ion binding
A	0004659	molecular_function	prenyltransferase activity
A	0005829	cellular_component	cytosol
A	0008360	biological_process	regulation of cell shape
A	0008834	molecular_function	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
A	0009252	biological_process	peptidoglycan biosynthetic process
A	0016094	biological_process	polyprenol biosynthetic process
A	0016740	molecular_function	transferase activity
A	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
A	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
A	0046872	molecular_function	metal ion binding
A	0071555	biological_process	cell wall organization
B	0000287	molecular_function	magnesium ion binding
B	0004659	molecular_function	prenyltransferase activity
B	0005829	cellular_component	cytosol
B	0008360	biological_process	regulation of cell shape
B	0008834	molecular_function	ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] activity
B	0009252	biological_process	peptidoglycan biosynthetic process
B	0016094	biological_process	polyprenol biosynthetic process
B	0016740	molecular_function	transferase activity
B	0016765	molecular_function	transferase activity, transferring alkyl or aryl (other than methyl) groups
B	0045547	molecular_function	ditrans,polycis-polyprenyl diphosphate synthase [(2E,6E)-farnesyl diphosphate specific] activity
B	0046872	molecular_function	metal ion binding
B	0071555	biological_process	cell wall organization

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue M2K A 301

Chain	Residue
A	MET27
A	HOH416
A	HOH417
A	ASP28
A	GLY29
A	ASN30
A	ASN31
A	HIS45
A	ALA71
A	ASN76
A	ARG79

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site_id	AC2
Number of Residues	12
Details	binding site for residue M2E A 302

Chain	Residue
A	MET27
A	LYS49
A	LEU52
A	ALA71
A	LEU87
A	LEU90
A	LEU91
A	THR94
A	GLN98
A	ILE143
A	HOH464
A	HOH469

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site_id	AC3
Number of Residues	6
Details	binding site for residue CA B 301

Chain	Residue
A	HOH478
B	GLU16
B	ASP170
B	ASP172
B	HOH456
B	HOH512

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Functional Information from PROSITE/UniProt

site_id	PS01066
Number of Residues	18
Details	UPP_SYNTHASE Undecaprenyl pyrophosphate synthase family signature. DLLIRTGGdfRiSnFLLW

Chain	Residue	Details
A	ASP192-TRP209

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