PDB: 615 件ウェブページステータス検索Chemie searchBIRD

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1PDB	Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine Antifolate Complex with Human Dihydrofolate Reductase 分子名称: Dihydrofolate reductase 著者 Cody, V, Luft, J.R, Pangborn, W, Gangjee, A. 登録日 2003-05-19 公開日 2003-12-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
1PD9	Analysis of Three Crystal Structure Determinations of a 5-Methyl-6-N-Methylanilino Pyridopyrimidine antifolate Complex with Human Dihydrofolate Reductase 分子名称: 2,4-DIAMINO-5-METHYL-6-[(3,4,5-TRIMETHOXY-N-METHYLANILINO)METHYL]PYRIDO[2,3-D]PYRIMIDINE, Dihydrofolate reductase, SULFATE ION 著者 Cody, V, Luft, J.R, Pangborn, W, Gangjee, A. 登録日 2003-05-19 公開日 2003-12-09 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Analysis of three crystal structure determinations of a 5-methyl-6-N-methylanilino pyridopyrimidine antifolate complex with human dihydrofolate reductase. Acta Crystallogr.,Sect.D, 59, 2003
1OHJ	HUMAN DIHYDROFOLATE REDUCTASE, MONOCLINIC (P21) CRYSTAL FORM 分子名称: DIHYDROFOLATE REDUCTASE, N-(4-CARBOXY-4-{4-[(2,4-DIAMINO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-BUTYL)-PHTHALAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Galitsky, N, Luft, J.R, Pangborn, W. 登録日 1997-09-17 公開日 1998-04-29 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523. Biochemistry, 36, 1997
1RA9	DIHYDROFOLATE REDUCTASE COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) 分子名称: DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R, Kraut, J. 登録日 1996-10-28 公開日 1996-12-23 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RH3	DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) 分子名称: DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R, Kraut, J. 登録日 1996-11-27 公開日 1997-03-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RF7	STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH DIHYDROFOLATE 分子名称: CHLORIDE ION, DIHYDROFOLATE REDUCTASE, DIHYDROFOLIC ACID, ... 著者 Sawaya, M.R. 登録日 1996-10-24 公開日 1997-03-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RA1	DIHYDROFOLATE REDUCTASE COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) 分子名称: CALCIUM ION, DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R, Kraut, J. 登録日 1996-10-30 公開日 1996-12-23 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RA3	DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) 分子名称: BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, METHOTREXATE, ... 著者 Sawaya, M.R, Kraut, J. 登録日 1996-10-28 公開日 1996-12-23 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RA2	DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) 分子名称: DIHYDROFOLATE REDUCTASE, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R, Kraut, J. 登録日 1996-10-28 公開日 1996-12-23 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RA8	DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 2-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE 分子名称: 2'-MONOPHOSPHOADENOSINE-5'-DIPHOSPHATE, DIHYDROFOLATE REDUCTASE, FOLIC ACID 著者 Sawaya, M.R, Kraut, J. 登録日 1996-11-21 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RB3	DIHYDROFOLATE REDUCTASE COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) 分子名称: DIHYDROFOLATE REDUCTASE, METHOTREXATE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R, Kraut, J. 登録日 1996-11-26 公開日 1997-03-12 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1OHK	HUMAN DIHYDROFOLATE REDUCTASE, ORTHORHOMBIC (P21 21 21) CRYSTAL FORM 分子名称: DIHYDROFOLATE REDUCTASE, N-(4-CARBOXY-4-{4-[(2,4-DIAMINO-PTERIDIN-6-YLMETHYL)-AMINO]-BENZOYLAMINO}-BUTYL)-PHTHALAMIC ACID, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Galitsky, N, Luft, J.R, Pangborn, W. 登録日 1997-09-17 公開日 1998-05-27 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523. Biochemistry, 36, 1997
1RX7	STRUCTURE OF DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE 分子名称: DIHYDROFOLATE REDUCTASE, FOLIC ACID 著者 Sawaya, M.R. 登録日 1996-10-25 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RX1	DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) 分子名称: CALCIUM ION, DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R. 登録日 1996-09-19 公開日 1997-01-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RX8	DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE AND 2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE 分子名称: BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, FOLIC ACID, ... 著者 Sawaya, M.R. 登録日 1996-10-25 公開日 1997-03-12 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1S3V	Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry 分子名称: (2R,6S)-6-{[methyl(3,4,5-trimethoxyphenyl)amino]methyl}-1,2,5,6,7,8-hexahydroquinazoline-2,4-diamine, Dihydrofolate reductase, SULFATE ION 著者 Cody, V, Luft, J.R, Pangborn, W, Gangjee, A, Queener, S.F. 登録日 2004-01-14 公開日 2004-03-30 最終更新日 2011-07-13 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Acta Crystallogr.,Sect.D, 60, 2004
1RX4	DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND 2'-MONOPHOSPHOADENOSINE 5'-DIPHOSPHORIBOSE 分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, ... 著者 Sawaya, M.R. 登録日 1996-09-19 公開日 1997-01-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1S3W	Structure Determination of Tetrahydroquinazoline Antifoaltes in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry 分子名称: 6-(OCTAHYDRO-1H-INDOL-1-YLMETHYL)DECAHYDROQUINAZOLINE-2,4-DIAMINE, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Luft, J.R, Pangborn, W, Gangjee, A, Queener, S.F. 登録日 2004-01-14 公開日 2004-03-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Acta Crystallogr.,Sect.D, 60, 2004
1S3Y	Structure Determination of Tetrahydroquinazoline Antifolates in Complex with Human and Pneumocystis carinii Dihydrofolate Reductase: Correlations of Enzyme Selectivity and Stereochemistry 分子名称: 6-(OCTAHYDRO-1H-INDOL-1-YLMETHYL)DECAHYDROQUINAZOLINE-2,4-DIAMINE, Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Cody, V, Luft, J.R, Pangborn, W, Gangjee, A, Queener, S.F. 登録日 2004-01-14 公開日 2004-03-30 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure determination of tetrahydroquinazoline antifolates in complex with human and Pneumocystis carinii dihydrofolate reductase: correlations between enzyme selectivity and stereochemistry. Acta Crystallogr.,Sect.D, 60, 2004
1RX6	DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) 分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, ... 著者 Sawaya, M.R. 登録日 1996-09-19 公開日 1997-01-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RD7	DIHYDROFOLATE REDUCTASE COMPLEXED WITH FOLATE 分子名称: BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, FOLIC ACID 著者 Sawaya, M.R, Kraut, J. 登録日 1996-11-01 公開日 1996-12-23 最終更新日 2023-08-09 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RC4	DIHYDROFOLATE REDUCTASE COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) 分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, DIHYDROFOLATE REDUCTASE, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE 著者 Sawaya, M.R, Kraut, J. 登録日 1996-11-25 公開日 1997-03-12 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RX5	DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH 5,10-DIDEAZATETRAHYDROFOLATE 分子名称: 5,10-DIDEAZATETRAHYDROFOLIC ACID, DIHYDROFOLATE REDUCTASE 著者 Sawaya, M.R. 登録日 1996-09-19 公開日 1997-01-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RX9	DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (OXIDIZED FORM) 分子名称: BETA-MERCAPTOETHANOL, CALCIUM ION, DIHYDROFOLATE REDUCTASE, ... 著者 Sawaya, M.R, Kraut, J. 登録日 1996-10-25 公開日 1997-04-01 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997
1RX3	DIHYDROFOLATE REDUCTASE (E.C.1.5.1.3) COMPLEXED WITH METHOTREXATE AND NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE (REDUCED FORM) 分子名称: BETA-MERCAPTOETHANOL, DIHYDROFOLATE REDUCTASE, MANGANESE (II) ION, ... 著者 Sawaya, M.R. 登録日 1996-09-19 公開日 1997-01-11 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Loop and subdomain movements in the mechanism of Escherichia coli dihydrofolate reductase: crystallographic evidence. Biochemistry, 36, 1997

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