PDB: 227344 件ウェブページステータス検索Chemie searchBIRD

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2FZM	Structure of the E. coli PutA proline dehydrogenase domain reduced by dithionite and complexed with SO2 分子名称: Bifunctional protein putA, Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase), FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Tanner, J.J. 登録日 2006-02-09 公開日 2007-04-03 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Redox-induced changes in flavin structure and roles of flavin N(5) and the ribityl 2'-OH group in regulating PutA--membrane binding. Biochemistry, 46, 2007
2FZN	Structure of the E. coli PutA proline dehydrogenase domain reduced by dithionite and complexed with proline 分子名称: Bifunctional protein putA, Proline dehydrogenase (EC 1.5.99.8) (Proline oxidase), FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Tanner, J.J. 登録日 2006-02-09 公開日 2006-12-26 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Hydrogen Bonding Interactions of the 2-OH Ribityl Group and the N(5) Position of the FAD Cofactor Regulate PutA-membrane Associations in Escherichia coli To be Published
2FZP	Crystal structure of the USP8 interaction domain of human NRDP1 分子名称: ring finger protein 41 isoform 1 著者 Walker, J.R, Avvakumov, G.V, Xue, S, Newman, E.M, Butler-Cole, C, Finerty Jr, P.J, Weigelt, J, Sundstrom, M, Arrowsmith, C, Edwards, A, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) 登録日 2006-02-10 公開日 2006-03-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.87 Å) 主引用文献 Amino-terminal Dimerization, NRDP1-Rhodanese Interaction, and Inhibited Catalytic Domain Conformation of the Ubiquitin-specific Protease 8 (USP8). J.Biol.Chem., 281, 2006
2FZS	Crystal structure of E. coli ClpP with a Peptide Chloromethyl Ketone Covalently Bound at the Active Site 分子名称: ATP-dependent Clp protease proteolytic subunit, GLYCEROL, N~2~-[(BENZYLOXY)CARBONYL]-N-[(1S,2S)-2-HYDROXY-1-(4-HYDROXYBENZYL)PROPYL]-L-LEUCINAMIDE, ... 著者 Szyk, A, Maurizi, M.R. 登録日 2006-02-10 公開日 2006-05-23 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure at 1.9A of E. coli ClpP with a peptide covalently bound at the active site. J.Struct.Biol., 156, 2006
2FZT	CRYSTAL STRUCTURE OF a putative nucleic acid binding protein (TM0693) FROM THERMOTOGA MARITIMA MSB8 AT 2.05 A RESOLUTION 分子名称: ISOPROPYL ALCOHOL, hypothetical protein TM0693 著者 Joint Center for Structural Genomics (JCSG) 登録日 2006-02-10 公開日 2006-03-21 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of hypothetical protein (tm0693) from THERMOTOGA MARITIMA at 2.05 A resolution To be published
2FZU	Reduced enolate chromophore intermediate for GFP variant 分子名称: 1,2-ETHANEDIOL, Green fluorescent protein, MAGNESIUM ION 著者 Barondeau, D.P, Tainer, J.A, Getzoff, E.D. 登録日 2006-02-10 公開日 2006-03-14 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.25 Å) 主引用文献 Structural evidence for an enolate intermediate in GFP fluorophore biosynthesis. J.Am.Chem.Soc., 128, 2006
2FZV	Crystal Structure of an apo form of a Flavin-binding Protein from Shigella flexneri 分子名称: CALCIUM ION, CHLORIDE ION, putative arsenical resistance protein 著者 Vorontsov, I.I, Minasov, G, Brunzelle, J.S, Shuvalova, L, Collart, F.R, Joachimiak, A, Anderson, W.F, Midwest Center for Structural Genomics (MCSG) 登録日 2006-02-10 公開日 2006-02-21 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structure of an apo form of Shigella flexneri ArsH protein with an NADPH-dependent FMN reductase activity Protein Sci., 16, 2007
2FZW	Structure of the binary complex of the E67L mutant of human glutathione-dependent formaldehyde dehydrogenase with NAD(H) 分子名称: Alcohol dehydrogenase class III chi chain, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, ... 著者 Sanghani, P.C, Robinson, H. 登録日 2006-02-10 公開日 2006-06-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (1.84 Å) 主引用文献 Structure-function relationships in human glutathione-dependent formaldehyde dehydrogenase. Role of Glu-67 and Arg-368 in the catalytic mechanism. Biochemistry, 45, 2006
2FZZ	Factor Xa in complex with the inhibitor 1-(3-amino-1,2-benzisoxazol-5-yl)-6-(2'-(((3r)-3-hydroxy-1-pyrrolidinyl)methyl)-4-biphenylyl)-3-(trifluoromethyl)-1,4,5,6-tetrahydro-7h-pyrazolo[3,4-c]pyridin-7-one 分子名称: 1-(3-AMINO-1,2-BENZISOXAZOL-5-YL)-6-(2'-{[(3R)-3-HYDROXYPYRROLIDIN-1-YL]METHYL}BIPHENYL-4-YL)-3-(TRIFLUOROMETHYL)-1,4,5,6-TETRAHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE, Coagulation factor X 著者 Alexander, R.S. 登録日 2006-02-10 公開日 2006-06-27 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 1-[3-Aminobenzisoxazol-5'-yl]-3-trifluoromethyl-6-[2'-(3-(R)-hydroxy-N-pyrrolidinyl)methyl-[1,1']-biphen-4-yl]-1,4,5,6-tetrahydropyrazolo-[3,4-c]-pyridin-7-one (BMS-740808) a highly potent, selective, efficacious, and orally bioavailable inhibitor of blood coagulation factor Xa. Bioorg.Med.Chem.Lett., 16, 2006
2G00	Factor Xa in complex with the inhibitor 3-(6-(2'-((dimethylamino)methyl)-4-biphenylyl)-7-oxo-3-(trifluoromethyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridin-1-yl)benzamide 分子名称: 3-[6-{2'-[(DIMETHYLAMINO)METHYL]BIPHENYL-4-YL}-7-OXO-3-(TRIFLUOROMETHYL)-4,5,6,7-TETRAHYDRO-1H-PYRAZOLO[3,4-C]PYRIDIN-1-YL]BENZAMIDE, Coagulation factor X 著者 Alexander, R.S. 登録日 2006-02-10 公開日 2006-10-03 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Discovery of potent, efficacious, and orally bioavailable inhibitors of blood coagulation factor Xa with neutral P1 moieties. Bioorg.Med.Chem.Lett., 16, 2006
2G01	Pyrazoloquinolones as Novel, Selective JNK1 inhibitors 分子名称: 6-CHLORO-9-HYDROXY-1,3-DIMETHYL-1,9-DIHYDRO-4H-PYRAZOLO[3,4-B]QUINOLIN-4-ONE, C-jun-amino-terminal kinase-interacting protein 1, Mitogen-activated protein kinase 8, ... 著者 Abad-Zapatero, C. 登録日 2006-02-10 公開日 2006-04-18 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors. Bioorg.Med.Chem.Lett., 16, 2006
2G02	Nisin cyclase 分子名称: Nisin biosynthesis protein nisC, ZINC ION 著者 Nair, S.K. 登録日 2006-02-10 公開日 2006-05-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Structure and Mechanism of the Lantibiotic Cyclase Involved in Nisin Biosynthesis Science, 311, 2006
2G03	Structure of a putative cell filamentation protein from Neisseria meningitidis. 分子名称: ACETIC ACID, ISOPROPYL ALCOHOL, hypothetical protein NMA0004 著者 Cuff, M.E, Bigelow, L, Bargassa, M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2006-02-10 公開日 2006-03-21 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Structure of a putative cell filamentation protein from Neisseria meningitidis. To be Published
2G04	Crystal structure of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv 分子名称: PROBABLE FATTY-ACID-CoA RACEMASE FAR 著者 Lee, K.S, Park, S.M, Rhee, K.H, Bang, W.G, Hwang, K.Y, Chi, Y.M. 登録日 2006-02-11 公開日 2007-01-02 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Crystal structure of fatty acid-CoA racemase from Mycobacterium tuberculosis H37Rv Proteins, 64, 2006
2G06	X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, with bound magnesium(II) 分子名称: Cytosolic 5'-nucleotidase III, MAGNESIUM ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID) 著者 Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-02-11 公開日 2006-04-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281, 2006
2G07	X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, phospho-enzyme intermediate analog with Beryllium fluoride 分子名称: Cytosolic 5'-nucleotidase III, MAGNESIUM ION 著者 Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-02-11 公開日 2006-04-04 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281, 2006
2G08	X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, product-transition complex analog with Aluminum fluoride 分子名称: ALUMINUM FLUORIDE, Cytosolic 5'-nucleotidase III, MAGNESIUM ION 著者 Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-02-11 公開日 2006-04-04 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281, 2006
2G09	X-ray structure of mouse pyrimidine 5'-nucleotidase type 1, product complex 分子名称: Cytosolic 5'-nucleotidase III, MAGNESIUM ION, PHOSPHATE ION, ... 著者 Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-02-11 公開日 2006-04-04 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281, 2006
2G0A	X-ray structure of mouse pyrimidine 5'-nucleotidase type 1 with lead(II) bound in active site 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Cytosolic 5'-nucleotidase III, LEAD (II) ION 著者 Bitto, E, Bingman, C.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) 登録日 2006-02-11 公開日 2006-04-04 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Structure of pyrimidine 5'-nucleotidase type 1. Insight into mechanism of action and inhibition during lead poisoning. J.Biol.Chem., 281, 2006
2G0B	The structure of FeeM, an N-acyl amino acid synthase from uncultured soil microbes 分子名称: FeeM, N-DODECANOYL-L-TYROSINE 著者 Van Wagoner, R.M, Clardy, J. 登録日 2006-02-11 公開日 2006-09-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 FeeM, an N-Acyl Amino Acid Synthase from an Uncultured Soil Microbe: Structure, Mechanism, and Acyl Carrier Protein Binding. Structure, 14, 2006
2G0C	Structure of the RNA binding domain (residues 404-479) of the Bacillus subtilis YxiN protein 分子名称: ATP-dependent RNA helicase dbpA, SULFATE ION 著者 McKay, D.B. 登録日 2006-02-11 公開日 2006-04-18 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 The domain of the Bacillus subtilis DEAD-box helicase YxiN that is responsible for specific binding of 23S rRNA has an RNA recognition motif fold. RNA, 12, 2006
2G0D	Nisin cyclase 分子名称: Nisin biosynthesis protein nisC, ZINC ION 著者 Nair, S.K. 登録日 2006-02-12 公開日 2006-05-23 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis Science, 311, 2006
2G0E	Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs 分子名称: 3-[C-[N'-(3-CARBAMIMIDOYL-BENZYLIDENIUM)-HYDRAZINO]-[[AMINOMETHYLIDENE]AMINIUM]-IMINOMETHYL]-BENZAMIDINIUM, HTH-type transcriptional regulator qacR, SULFATE ION 著者 Schuman, J.T. 登録日 2006-02-12 公開日 2008-04-08 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.88 Å) 主引用文献 Structure of QacR Multidrug Transcriptional Regulator Bound to Trivalent and Bivalent Diamidine Drugs To be Published
2G0F	Crystal Structure of P144A mutant of E.coli CcmG protein 分子名称: Thiol:disulfide interchange protein dsbE 著者 Ouyang, N, Gao, Y.G, Hu, H.Y, Xia, Z.X. 登録日 2006-02-12 公開日 2006-12-05 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structures of E. coli CcmG and its mutants reveal key roles of the N-terminal beta-sheet and the fingerprint region Proteins, 65, 2006
2G0G	Structure-based drug design of a novel family of PPAR partial agonists: virtual screening, x-ray crystallography and in vitro/in vivo biological activities 分子名称: 3-FLUORO-N-[1-(4-FLUOROPHENYL)-3-(2-THIENYL)-1H-PYRAZOL-5-YL]BENZENESULFONAMIDE, Peroxisome proliferator-activated receptor gamma 著者 Lu, I.L, Peng, Y.H, Huang, C.F, Lin, Y.T, Hsu, J.T.A, Wu, S.Y. 登録日 2006-02-13 公開日 2006-05-16 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.54 Å) 主引用文献 Structure-Based Drug Design of a Novel Family of PPARgamma Partial Agonists: Virtual Screening, X-ray Crystallography, and in Vitro/in Vivo Biological Activities J.Med.Chem., 49, 2006

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