2FZW
Structure of the binary complex of the E67L mutant of human glutathione-dependent formaldehyde dehydrogenase with NAD(H)
Summary for 2FZW
| Entry DOI | 10.2210/pdb2fzw/pdb |
| Descriptor | Alcohol dehydrogenase class III chi chain, ZINC ION, PHOSPHATE ION, ... (6 entities in total) |
| Functional Keywords | s-nitrosoglutathione reductase, glutathione-dependent formaldehyde dehydrogenase, oxidoreductase |
| Biological source | Homo sapiens (human) |
| Cellular location | Cytoplasm: P11766 |
| Total number of polymer chains | 2 |
| Total formula weight | 81201.68 |
| Authors | Sanghani, P.C.,Robinson, H. (deposition date: 2006-02-10, release date: 2006-06-13, Last modification date: 2024-02-14) |
| Primary citation | Sanghani, P.C.,Davis, W.I.,Zhai, L.,Robinson, H. Structure-function relationships in human glutathione-dependent formaldehyde dehydrogenase. Role of Glu-67 and Arg-368 in the catalytic mechanism. Biochemistry, 45:4819-4830, 2006 Cited by PubMed: 16605250DOI: 10.1021/bi052554q PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.84 Å) |
Structure validation
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