2FZW
Structure of the binary complex of the E67L mutant of human glutathione-dependent formaldehyde dehydrogenase with NAD(H)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Alcohol dehydrogenase class III chi chain | polymer | 373 | 39625.0 | 2 | UniProt (P11766) Pfam (PF08240) Pfam (PF00107) | Homo sapiens (human) | S- hydroxymethyl, glutathione dehydrogenase, Glutathione- dependent formaldehyde dehydrogenase, FDH |
| 2 | C, D, H, I (A, B) | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) | |||
| 3 | E, J, K (A, B) | PHOSPHATE ION | non-polymer | 95.0 | 3 | Chemie (PO4) | |||
| 4 | F, L (A, B) | POTASSIUM ION | non-polymer | 39.1 | 2 | Chemie (K) | |||
| 5 | G, M (A, B) | NICOTINAMIDE-ADENINE-DINUCLEOTIDE | non-polymer | 663.4 | 2 | Chemie (NAD) | |||
| 6 | N, O (A, B) | water | water | 18.0 | 1021 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 373 (UniProt: P11766)
| PDB | External Database | Details |
|---|---|---|
| Leu 67 | Glu 67 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 79250.1 | |
| Non-Polymers* | Number of molecules | 11 |
| Total formula weight | 1951.6 | |
| All* | Total formula weight | 81201.7 |
