7RFE
 
 | | HUMAN IMPDH1 TREATED WITH GTP, IMP, AND NAD+; INTERFACE-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-14 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RGM
 | | HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH ATP, IMP, NAD+, OCTAMER-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.8 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RER
 | | HUMAN IMPDH1 TREATED WITH ATP, IMP, AND NAD+ | | 分子名称: | INOSINIC ACID, Isoform 5 of Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-13 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (2.6 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RFF
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7RGI
 | | HUMAN RETINAL VARIANT IMPDH1(546) TREATED WITH GTP, ATP, IMP, NAD+; INTERFACE-CENTERED | | 分子名称: | INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase 1, NICOTINAMIDE-ADENINE-DINUCLEOTIDE | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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7RGD
 | | HUMAN RETINAL VARIANT IMPDH1(595) TREATED WITH GTP, ATP, IMP, NAD+, OCTAMER-CENTERED | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, INOSINIC ACID, ... | | 著者 | Burrell, A.L, Kollman, J.M. | | 登録日 | 2021-07-15 | | 公開日 | 2022-01-12 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | IMPDH1 retinal variants control filament architecture to tune allosteric regulation.
Nat.Struct.Mol.Biol., 29, 2022
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5YVK
 | | Crystal structure of a cyclase Famc1 from Fischerella ambigua UTEX 1903 | | 分子名称: | CALCIUM ION, amino({3-[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]propyl}amino)methaniminium, cyclase | | 著者 | Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2017-11-26 | | 公開日 | 2018-11-07 | | 最終更新日 | 2024-03-27 | | 実験手法 | X-RAY DIFFRACTION (1.292 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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8FE9
 | | Crystal structure of Ack1 kinase K161Q mutant in complex with the selective inhibitor (R)-9b | | 分子名称: | Activated CDC42 kinase 1, N-[(1S)-1-benzyl-2-[(6-chloro-2-oxo-1H-quinolin-4-yl)methylamino]-2-oxo-ethyl]-4-hydroxy-2-oxo-1H-quinoline-6-carbo | | 著者 | Paung, Y, Kan, Y, Seeliger, M.S, Miller, W.T. | | 登録日 | 2022-12-06 | | 公開日 | 2023-03-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Biochemical Studies of Systemic Lupus Erythematosus-Associated Mutations in Nonreceptor Tyrosine Kinases Ack1 and Brk.
Biochemistry, 62, 2023
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5YVP
 | | Crystal structure of an apo form cyclase Filc1 from Fischerella sp. TAU | | 分子名称: | CALCIUM ION, TETRAETHYLENE GLYCOL, cyclase A | | 著者 | Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2017-11-27 | | 公開日 | 2018-11-07 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.051 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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5Z54
 | | Crystal structure of a cyclase Hpiu5 from Fischerella sp. ATCC 43239 in complex with cyclo-L-Arg-D-Pro | | 分子名称: | 12-epi-hapalindole C/U synthase, CALCIUM ION, amino({3-[(3S,8aS)-1,4-dioxooctahydropyrrolo[1,2-a]pyrazin-3-yl]propyl}amino)methaniminium | | 著者 | Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2018-01-17 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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5Z53
 | | Crystal structure of a cyclase Filc from Fischerella sp. in complex with cyclo-L-Arg-D-Pro | | 分子名称: | 12-epi-hapalindole U synthase, CALCIUM ION, SULFATE ION, ... | | 著者 | Hu, X.Y, Liu, W.D, Chen, C.C, Guo, R.T. | | 登録日 | 2018-01-16 | | 公開日 | 2018-12-19 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | | 主引用文献 | The Crystal Structure of a Class of Cyclases that Catalyze the Cope Rearrangement
Angew. Chem. Int. Ed. Engl., 57, 2018
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7RPR
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7RPS
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7RDE
 | | Human Triose Phosphate Isomerase Q181P | | 分子名称: | BROMIDE ION, CALCIUM ION, Triosephosphate isomerase | | 著者 | VanDemark, A.P, Kowalski, J. | | 登録日 | 2021-07-09 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency.
Dis Model Mech, 15, 2022
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6GYB
 | | Cryo-EM structure of the bacteria-killing type IV secretion system core complex from Xanthomonas citri | | 分子名称: | VirB10 protein, VirB7, VirB9 protein | | 著者 | Sgro, G.G, Costa, T.R.D, Farah, C.S, Waksman, G. | | 登録日 | 2018-06-28 | | 公開日 | 2018-10-24 | | 最終更新日 | 2019-12-11 | | 実験手法 | ELECTRON MICROSCOPY (3.28 Å) | | 主引用文献 | Cryo-EM structure of the bacteria-killing type IV secretion system core complex from Xanthomonas citri.
Nat Microbiol, 3, 2018
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1BDA
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8FG0
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6GXF
 | | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography: RADDAM1 | | 分子名称: | Fluoroacetate dehalogenase | | 著者 | Schulz, E.C, Mehrabi, P, Mueller-Werkmeister, H, Tellkamp, F, Stuart, W, Persch, E, De Gasparo, R, Diederich, F, Pai, E.F, Miller, R.J.D. | | 登録日 | 2018-06-27 | | 公開日 | 2018-10-17 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The hit-and-return system enables efficient time-resolved serial synchrotron crystallography.
Nat. Methods, 15, 2018
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8GV2
 | | Crystal structure of anti-FX IgG fab without FAST-Ig mutations | | 分子名称: | 1,2-ETHANEDIOL, Anti-factor X IgG fab heavy chain, Anti-factor X IgG fab light chain | | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | | 登録日 | 2022-09-14 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.274 Å) | | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A.
Mabs, 15, 2023
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8GV1
 | | Crystal structure of anti-FX IgG fab with FAST-Ig mutations | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, Anti-factor X IgG fab heavy chain, ... | | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | | 登録日 | 2022-09-14 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.186 Å) | | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A.
Mabs, 15, 2023
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8GUZ
 | | Crystal structure of anti-FIXa IgG fab with FAST-Ig mutations | | 分子名称: | 1,2-ETHANEDIOL, Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain | | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | | 登録日 | 2022-09-14 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A.
Mabs, 15, 2023
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8GV0
 | | Crystal structure of anti-FIXa IgG fab without FAST-Ig mutations | | 分子名称: | Anti-factor IXa IgG fab heavy chain, Anti-factor IXa IgG fab light chain | | 著者 | Koga, H, Yamano, T, Fukami, T.A, Sampei, Z, Shiraiwa, H, Torizawa, T. | | 登録日 | 2022-09-14 | | 公開日 | 2023-06-28 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | | 主引用文献 | Efficient production of bispecific antibody by FAST-Ig TM and its application to NXT007 for the treatment of hemophilia A.
Mabs, 15, 2023
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6HIU
 | | Cytochrome P460 from Methylococcus capsulatus (Bath) | | 分子名称: | Cytochrome P460, GLYCEROL, HEME C, ... | | 著者 | Adams, H, Chicano, T.M, Hough, M.A. | | 登録日 | 2018-08-31 | | 公開日 | 2019-03-20 | | 最終更新日 | 2019-05-01 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | One fold, two functions: cytochrome P460 and cytochromec'-beta from the methanotrophMethylococcus capsulatus(Bath).
Chem Sci, 10, 2019
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7RCU
 | | Synthetic Max homodimer mimic in complex with DNA | | 分子名称: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 2-(2,5-dioxopyrrolidin-1-yl)acetamide, ACETAMIDE, ... | | 著者 | Speltz, T, Qiao, Z, Shangguan, S, Fanning, S, Greene, J, Moellering, R. | | 登録日 | 2021-07-08 | | 公開日 | 2022-09-14 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | | 主引用文献 | Targeting MYC with modular synthetic transcriptional repressors derived from bHLH DNA-binding domains.
Nat.Biotechnol., 41, 2023
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5ZJ9
 | | human D-amino acid oxidase complexed with 5-chlorothiophene-3-carboxylic acid | | 分子名称: | 5-chloro thiophene-3-carboxylic acid, D-amino-acid oxidase, FLAVIN-ADENINE DINUCLEOTIDE | | 著者 | Kato, Y, Hin, N, Maita, N, Thomas, A.G, Kurosawa, S, Rojas, C, Yorita, K, Slusher, B.S, Fukui, K, Tsukamoto, T. | | 登録日 | 2018-03-19 | | 公開日 | 2018-10-10 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for potent inhibition of d-amino acid oxidase by thiophene carboxylic acids
Eur J Med Chem, 159, 2018
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