PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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6OBS	PP1 Y134K 分子名称: GLYCEROL, MANGANESE (II) ION, PHOSPHATE ION, ... 著者 Choy, M.S, Moon, T.M, Bray, J.A, Archuleta, T.L, Shi, W, Peti, W, Page, R. 登録日 2019-03-21 公開日 2019-09-18 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.803 Å) 主引用文献 SDS22 selectively recognizes and traps metal-deficient inactive PP1. Proc.Natl.Acad.Sci.USA, 116, 2019
8E4R	Room-temperature X-ray structure of SARS-CoV-2 main protease H41A miniprecursor mutant in complex with GC373 分子名称: (1S,2S)-2-({N-[(benzyloxy)carbonyl]-L-leucyl}amino)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propane-1-sulfonic acid, Replicase polyprotein 1ab 著者 Coates, L, Kneller, D.W, Kovalevsky, A. 登録日 2022-08-18 公開日 2022-11-23 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Unmasking the Conformational Stability and Inhibitor Binding to SARS-CoV-2 Main Protease Active Site Mutants and Miniprecursor. J.Mol.Biol., 434, 2022
8UPI	Structure of a periplasmic peptide binding protein from Mesorhizobium sp. AP09 bound to aminoserine 分子名称: 1,2-ETHANEDIOL, AMINOSERINE, CALCIUM ION, ... 著者 Frkic, R.L, Smith, O.B, Rahman, M, Kaczmarski, J.A, Jackson, C.J. 登録日 2023-10-22 公開日 2023-11-08 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l-Amino Acid Amides. Biochemistry, 63, 2024
6FES	Crystal structure of novel repeat protein BRIC2 fused to DARPin D12 分子名称: 1,2-ETHANEDIOL, D12_BRIC2, a synthetic protein,D12_BRIC2, ... 著者 ElGamacy, M, Coles, M, Ernst, P, Zhu, H, Hartmann, M.D, Plueckthun, A, Lupas, A. 登録日 2018-01-03 公開日 2018-09-05 最終更新日 2025-10-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 An Interface-Driven Design Strategy Yields a Novel, Corrugated Protein Architecture. ACS Synth Biol, 7, 2018
9AV1	Crystal structure of E. coli GuaB dCBS with inhibitor GNE9123 分子名称: INOSINIC ACID, Inosine-5'-monophosphate dehydrogenase, N-(6-chloropyridin-3-yl)-N~2~-(1,4-dihydro-2H-pyrano[3,4-c]quinolin-9-yl)-L-alaninamide 著者 Harris, S.F, Wu, P. 登録日 2024-03-01 公開日 2025-01-15 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Discovery of GuaB inhibitors with efficacy against Acinetobacter baumannii infection. Mbio, 15, 2024
7POY	Spin labeled IPNS S55C variant in complex with Fe, ACV and NO 分子名称: FE (III) ION, Isopenicillin N synthase, L-D-(A-AMINOADIPOYL)-L-CYSTEINYL-D-VALINE, ... 著者 Rabe, P, Clifton, I, Walla, C, Schofield, C.J. 登録日 2021-09-10 公開日 2022-07-20 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Spectroscopic studies reveal details of substrate-induced conformational changes distant from the active site in isopenicillin N synthase. J.Biol.Chem., 298, 2022
6QW7	Crystal structure of L2 complexed with relebactam (16 hour soak) 分子名称: (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase, D-SERINE 著者 Tooke, C.L, Hinchliffe, P, Spencer, J. 登録日 2019-03-05 公開日 2019-08-21 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (1.78 Å) 主引用文献 Molecular Basis of Class A beta-Lactamase Inhibition by Relebactam. Antimicrob.Agents Chemother., 63, 2019
6QVP	Crystal structure of the peptidoglycan-binding domain of SiiA from Salmonella enterica 分子名称: Inner membrane protein, PHOSPHATE ION 著者 Kirchweger, P, Muller, Y.A. 登録日 2019-03-04 公開日 2019-08-28 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural and functional characterization of SiiA, an auxiliary protein from the SPI4-encoded type 1 secretion system from Salmonella enterica. Mol.Microbiol., 112, 2019
6XSZ	The structure of the M60 catalytic domain from Clostridium perfringens ZmpC 分子名称: 1,2-ETHANEDIOL, ZINC ION, ZmpC Glycopeptidase 著者 Pluvinage, B, Boraston, A.B. 登録日 2020-07-16 公開日 2021-02-03 最終更新日 2023-10-18 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Molecular insights into architecturally complex glycopeptidases Proc.Natl.Acad.Sci.USA, 2021
8V98	GII.24 Loreto 1972 norovirus protruding domain 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Capsid protein VP1 著者 Kher, G, Prewitt, A, Pancera, M, Hansman, G. 登録日 2023-12-07 公開日 2024-06-19 最終更新日 2024-07-31 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Development of a broad-spectrum therapeutic Fc-nanobody for human noroviruses. J.Virol., 98, 2024
9JYS	Crystal structure of the PIN1 and fragment 5 complex. 分子名称: 3,6,9,12,15,18,21-HEPTAOXATRICOSANE-1,23-DIOL, 4-(aminomethyl)-N,N-dimethyl-aniline, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, ... 著者 Xiao, Q.J, Wu, T.T, Shu, H.L, Qin, W.M. 登録日 2024-10-12 公開日 2025-10-15 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Fragment-Based Compound Screening Based on PIN1 Crystals To Be Published
9AVD	Mitochondrial fission 1 protein Fis1 structure T34D mutation 分子名称: Mitochondrial fission 1 protein 著者 Mathews, I.I, Pokhrel, S, Wakatsuki, S. 登録日 2024-03-01 公開日 2025-05-21 実験手法 X-RAY DIFFRACTION (2.51 Å) 主引用文献 A hidden cysteine in Fis1 targeted to prevent excessive mitochondrial fission and dysfunction under oxidative stress. Nat Commun, 16, 2025
367D	1.2 A STRUCTURE DETERMINATION OF THE D(CG(5-BRU)ACG)2/5-BROMO-9-AMINO-DACA COMPLEX 分子名称: 5'-D(*CP*GP*(BRU)P*AP*CP*G)-3', 5-BROMO-9-AMINO-N-ETHYL(DIAMINOMETHYL)ACRIDINE-4-CARBOXAMIDE, BROMIDE ION 著者 Todd, A.K, Adams, A, Thorpe, J.H, Denny, W.A, Cardin, C.J. 登録日 1997-12-19 公開日 2003-03-04 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Major groove binding and 'DNA-induced' fit in the intercalation of a derivative of the mixed topoisomerase I/II poison N-(2-(dimethlyamino)ethyl)acridine-4-carboxamide (DACA) into DNA: X-ray structure complexed to d(CG(5Br-U)ACG)2 at 1.3-angstrom resolution J.Med.Chem., 42, 1999
5L9I	Crystal structure of the periplasmic binding protein MotA in complex with DFG from A. tumefaciens B6 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... 著者 Marty, L, Morera, S. 登録日 2016-06-10 公開日 2016-09-21 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Structural Basis for High Specificity of Amadori Compound and Mannopine Opine Binding in Bacterial Pathogens. J.Biol.Chem., 291, 2016
6N53	Crystal structure of human uridine-cytidine kinase 2 complexed with 2'-azidouridine monophosphate 分子名称: 2'-deoxy-2'-triaza-1,2-dien-2-ium-1-yl-uridine-5'-monophosphate, GLYCEROL, MAGNESIUM ION, ... 著者 Cuthbert, B.J, Nainar, S, Spitale, R.C, Goulding, C.W. 登録日 2018-11-21 公開日 2019-11-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 An optimized chemical-genetic method for cell-specific metabolic labeling of RNA. Nat.Methods, 17, 2020
9S87	Crystal structure of the BRI1 ectodomain from Arabidopsis thaliana in complex with castasterone. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Caregnato, A, Hothorn, M. 登録日 2025-08-05 公開日 2025-09-10 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 A mechanistic framework for the recognition of chemically diverse brassinosteroids by BRI1-family receptor kinases. To Be Published
9S8S	Crystal structure of the BRI1 ectodomain from Arabidopsis thaliana in complex with typhasterol. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Caregnato, A, Hothorn, M. 登録日 2025-08-05 公開日 2025-09-10 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 A mechanistic framework for the recognition of chemically diverse brassinosteroids by BRI1-family receptor kinases. To Be Published
9S80	Crystal structure of the BRL3 ectodomain from Arabidopsis thaliana in complex with brassinolide. 分子名称: 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... 著者 Hohmann, U, Hothorn, M. 登録日 2025-08-05 公開日 2025-09-10 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 A mechanistic framework for the recognition of chemically diverse brassinosteroids by BRI1-family receptor kinases. To Be Published
6PKU	Guinea pig N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase (NAGPA) catalytic domain (C51S C221S) in complex with N-acetyl-alpha-D-glucosamine (alpha-GlcNAc) and mannose 6-phosphate (M6P) 分子名称: 2-acetamido-2-deoxy-alpha-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 6-O-phosphono-alpha-D-mannopyranose, ... 著者 Gorelik, A, Illes, K, Nagar, B. 登録日 2019-06-29 公開日 2020-02-19 最終更新日 2024-10-23 実験手法 X-RAY DIFFRACTION (1.949 Å) 主引用文献 Crystal Structure of the Mannose-6-Phosphate Uncovering Enzyme. Structure, 28, 2020
7OR2	Crystal structure of UDP-N-acetylenolpyruvoylglucosamine reductase (MurB) from Pseudomonas aeruginosa in complex with FAD and a pyrazole derivative (fragment 4) 分子名称: 5-methyl-1-phenyl-pyrazole-4-carboxylic acid, FLAVIN-ADENINE DINUCLEOTIDE, UDP-N-acetylenolpyruvoylglucosamine reductase 著者 Acebron-Garcia de Eulate, M, Blundell, T.L, Kim, S.Y, Mendes, V, Abell, C. 登録日 2021-06-04 公開日 2021-11-03 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Discovery of Novel Inhibitors of Uridine Diphosphate- N -Acetylenolpyruvylglucosamine Reductase (MurB) from Pseudomonas aeruginosa , an Opportunistic Infectious Agent Causing Death in Cystic Fibrosis Patients. J.Med.Chem., 65, 2022
6MUH	Fluoroacetate dehalogenase, room temperature structure solved by serial 1 degree oscillation crystallography 分子名称: Fluoroacetate dehalogenase 著者 Finke, A.D, Wierman, J.L, Pare-Labrosse, O, Sarrachini, A, Besaw, J, Mehrabi, P, Gruner, S.M, Miller, R.J.D. 登録日 2018-10-23 公開日 2019-03-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Fixed-target serial oscillation crystallography at room temperature. IUCrJ, 6, 2019
8QFM	Ergothioneine dioxygenase from Thermocatellispora tengchongensis in complex with manganese 分子名称: 1,2-ETHANEDIOL, Cysteine dioxygenase, DI(HYDROXYETHYL)ETHER, ... 著者 Vasseur, C.M, Seebeck, F.P. 登録日 2023-09-04 公開日 2023-12-27 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Enzyme-Catalyzed Oxidative Degradation of Ergothioneine. Angew.Chem.Int.Ed.Engl., 63, 2024
8Y59	Crystal structure of TRIM21 PRYSPRY (D355A) in complex with (S)-hydroxyl-acepromazine. 分子名称: (1~{S})-1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanol, E3 ubiquitin-protein ligase TRIM21 著者 Lu, P, Cheng, Y, Xue, L, Ren, X, Huang, N, Han, T. 登録日 2024-01-31 公開日 2024-10-09 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell, 187, 2024
8Y5B	Crystal structure of TRIM21 PRYSPRY (D355A) in complex with (R)-hydroxyl-acepromazine. 分子名称: (1~{R})-1-[10-[3-(dimethylamino)propyl]phenothiazin-2-yl]ethanol, E3 ubiquitin-protein ligase TRIM21 著者 Lu, P, Cheng, Y, Xue, L, Ren, X, Huang, N, Han, T. 登録日 2024-01-31 公開日 2024-10-09 最終更新日 2024-12-25 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Selective degradation of multimeric proteins by TRIM21-based molecular glue and PROTAC degraders. Cell, 187, 2024
5WHM	Crystal Structure of IclR Family Transcriptional Regulator from Brucella abortus 分子名称: 1,2-ETHANEDIOL, ACETIC ACID, CALCIUM ION, ... 著者 Kim, Y, Wu, R, Tesar, C, Endres, M, Babnigg, G, Crosson, S, Joachimiak, A, Midwest Center for Structural Genomics (MCSG) 登録日 2017-07-17 公開日 2017-08-23 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Molecular control of gene expression byBrucellaBaaR, an IclR-type transcriptional repressor. J. Biol. Chem., 293, 2018

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