6QW7
Crystal structure of L2 complexed with relebactam (16 hour soak)
Summary for 6QW7
| Entry DOI | 10.2210/pdb6qw7/pdb |
| Descriptor | Beta-lactamase, D-SERINE, (2S,5R)-1-formyl-N-(piperidin-4-yl)-5-[(sulfooxy)amino]piperidine-2-carboxamide, ... (4 entities in total) |
| Functional Keywords | inhibitor, relebactam, diazabicyclooctane, antibiotic resistance., antimicrobial protein |
| Biological source | Stenotrophomonas maltophilia |
| Total number of polymer chains | 2 |
| Total formula weight | 59091.94 |
| Authors | Tooke, C.L.,Hinchliffe, P.,Spencer, J. (deposition date: 2019-03-05, release date: 2019-08-21, Last modification date: 2024-01-24) |
| Primary citation | Tooke, C.L.,Hinchliffe, P.,Lang, P.A.,Mulholland, A.J.,Brem, J.,Schofield, C.J.,Spencer, J. Molecular Basis of Class A beta-Lactamase Inhibition by Relebactam. Antimicrob.Agents Chemother., 63:-, 2019 Cited by PubMed: 31383664DOI: 10.1128/AAC.00564-19 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.78 Å) |
Structure validation
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