3LA6
 
 | | Octameric kinase domain of the E. coli tyrosine kinase Wzc with bound ADP | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Tyrosine-protein kinase wzc | | 著者 | Gruszczyk, J, Nessler, S, Gueguen-Chaignon, V, Vigouroux, A, Bechet, E, Grangeasse, C. | | 登録日 | 2010-01-06 | | 公開日 | 2010-08-25 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Identification of structural and molecular determinants of the tyrosine-kinase Wzc and implications in capsular polysaccharide export
Mol.Microbiol., 77, 2010
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1PPW
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4AW9
 | | Crystal structure of active legumain in complex with YVAD-CMK | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ACE-TYR-VAL-ALA-ASP-CHLOROMETHYLKETONE, LEGUMAIN, ... | | 著者 | Dall, E, Brandstetter, H. | | 登録日 | 2012-06-01 | | 公開日 | 2013-06-26 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Mechanistic and Structural Studies on Legumain Explain its Zymogenicity, Distinct Activation Pathways, and Regulation
Proc.Natl.Acad.Sci.USA, 110, 2013
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2Q7W
 | | Structural Studies Reveals the Inactivation of E. coli L-aspartate aminotransferase (S)-4,5-amino-dihydro-2-thiophenecarboxylic acid (SADTA) via two mechanisms at pH 6.0 | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ... | | 著者 | Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D. | | 登録日 | 2007-06-07 | | 公開日 | 2007-09-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Inactivation of Escherichia coli l-Aspartate Aminotransferase by (S)-4-Amino-4,5-dihydro-2-thiophenecarboxylic Acid Reveals "A Tale of Two Mechanisms".
Biochemistry, 46, 2007
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2F00
 | | Escherichia coli MurC | | 分子名称: | MAGNESIUM ION, UDP-N-acetylmuramate--L-alanine ligase | | 著者 | Deva, T, Baker, E.N, Squire, C.J, Smith, C.A. | | 登録日 | 2005-11-10 | | 公開日 | 2006-10-24 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of Escherichia coliUDP-N-acetylmuramoyl:L-alanine ligase (MurC).
Acta Crystallogr.,Sect.D, 62, 2006
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2Q8M
 | | T-like Fructose-1,6-bisphosphatase from Escherichia coli with AMP, Glucose 6-phosphate, and Fructose 1,6-bisphosphate bound | | 分子名称: | 1,6-di-O-phosphono-beta-D-fructofuranose, 6-O-phosphono-beta-D-glucopyranose, ADENOSINE MONOPHOSPHATE, ... | | 著者 | Hines, J.K, Kruesel, C.E, Fromm, H.J, Honzatko, R.B. | | 登録日 | 2007-06-11 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure of Inhibited Fructose-1,6-bisphosphatase from Escherichia coli: DISTINCT ALLOSTERIC INHIBITION SITES FOR AMP AND GLUCOSE 6-PHOSPHATE AND THE CHARACTERIZATION OF A GLUCONEOGENIC SWITCH.
J.Biol.Chem., 282, 2007
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2EWF
 | | Crystal structure of the site-specific DNA nickase N.BspD6I | | 分子名称: | BROMIDE ION, Nicking endonuclease N.BspD6I | | 著者 | Kachalova, G.S, Bartunik, H.D, Artyukh, R.I, Rogulin, E.A, Perevyazova, T.A, Zheleznaya, L.A, Matvienko, N.I. | | 登録日 | 2005-11-03 | | 公開日 | 2006-11-21 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural analysis of the heterodimeric type IIS restriction endonuclease R.BspD6I acting as a complex between a monomeric site-specific nickase and a catalytic subunit.
J.Mol.Biol., 384, 2008
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1UW8
 | | CRYSTAL STRUCTURE OF OXALATE DECARBOXYLASE | | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MANGANESE (II) ION, OXALATE DECARBOXYLASE OXDC | | 著者 | Just, V.J, Stevenson, C.E.M, Bowater, L, Tanner, A, Lawson, D.M, Bornemann, S. | | 登録日 | 2004-02-02 | | 公開日 | 2004-02-19 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A Closed Conformation of Bacillus Subtilis Oxalate Decarboxylase Oxdc Provides Evidence for the True Identity of the Active Site
J.Biol.Chem., 279, 2004
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2QB2
 | | Structural Studies Reveal the Inactivation of E. coli L-aspartate aminotransferase by (s)-4,5-dihydro-2thiophenecarboylic acid (SADTA) via two mechanisms (at pH 7.0). | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, 4-[({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYL)AMINO]THIOPHENE-2-CARBOXYLIC ACID, Aspartate aminotransferase, ... | | 著者 | Liu, D, Pozharski, E, Lepore, B, Fu, M, Silverman, R.B, Petsko, G.A, Ringe, D. | | 登録日 | 2007-06-15 | | 公開日 | 2007-12-04 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Inactivation of Escherichia coli L-aspartate aminotransferase by (S)-4-amino-4,5-dihydro-2-thiophenecarboxylic acid reveals "a tale of two mechanisms".
Biochemistry, 46, 2007
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1QRK
 | | HUMAN FACTOR XIII WITH STRONTIUM BOUND IN THE ION SITE | | 分子名称: | PROTEIN (COAGULATION FACTOR XIII), STRONTIUM ION | | 著者 | Fox, B.A, Yee, V.C, Pederson, L.C, Le Trong, I, Bishop, P.D, Stenkamp, R.E, Teller, D.C. | | 登録日 | 1999-06-14 | | 公開日 | 1999-07-02 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Identification of the calcium binding site and a novel ytterbium site in blood coagulation factor XIII by x-ray crystallography.
J.Biol.Chem., 274, 1999
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2NSM
 | | Crystal structure of the human carboxypeptidase N (Kininase I) catalytic domain | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Carboxypeptidase N catalytic chain, SULFATE ION | | 著者 | Keil, C, Maskos, K, Than, M, Hoopes, J.T, Huber, R, Tan, F, Deddish, P.A, Erdoes, E.G, Skidgel, R.A, Bode, W. | | 登録日 | 2006-11-05 | | 公開日 | 2007-04-24 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal structure of the human carboxypeptidase N (kininase I) catalytic domain
J.Mol.Biol., 366, 2007
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2O1C
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2Y1K
 | | STRUCTURE OF HUMAN BUTYRYLCHOLINESTERASE INHIBITED BY CBDP (12H SOAK): PHOSPHOSERINE ADDUCT | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, CHOLINESTERASE, ... | | 著者 | Carletti, E, Colletier, J.P, Nachon, F, Weik, M. | | 登録日 | 2010-12-08 | | 公開日 | 2011-06-29 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Reaction of Cresyl Saligenin Phosphate, the Organophosphorus Agent Implicated in Aerotoxic Syndrome, with Human Cholinesterases: Mechanistic Studies Employing Kinetics, Mass Spectrometry, and X-Ray Structure Analysis.
Chem.Res.Toxicol., 24, 2011
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1LMO
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5VH5
 | | Crystal Structure of Fc fragment of anti-TNFa antibody infliximab | | 分子名称: | ACETATE ION, Infliximab Fc, ZINC ION, ... | | 著者 | Mayclin, S.J, Edwards, T.E, Lerch, T.F, Conlan, H, Sharpe, P. | | 登録日 | 2017-04-12 | | 公開日 | 2017-05-03 | | 最終更新日 | 2023-10-04 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Infliximab crystal structures reveal insights into self-association.
MAbs, 9, 2017
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1LMN
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4JXG
 | | Crystal Structure of AmpC beta-lactamase from E. coli in Complex with Oxacillin | | 分子名称: | (2R,4S)-5,5-dimethyl-2-[(1R)-1-{[(5-methyl-3-phenyl-1,2-oxazol-4-yl)carbonyl]amino}-2-oxoethyl]-1,3-thiazolidine-4-carb oxylic acid, Beta-lactamase, PHOSPHATE ION, ... | | 著者 | Wallar, B.J, Powers, R.A, Docter, B.E. | | 登録日 | 2013-03-28 | | 公開日 | 2014-10-29 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Complexed structures of AmpC beta-lactamase
To be Published
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2XFW
 | | Structure of the E192N mutant of E. coli N-acetylneuraminic acid lyase in complex with pyruvate in crystal form III | | 分子名称: | N-ACETYLNEURAMINIC ACID LYASE, PENTAETHYLENE GLYCOL, PYRUVIC ACID | | 著者 | Campeotto, I, Murshudov, G.N, Bolt, A.H, Trinh, C.H, Phillips, S.E.V, Nelson, A, Pearson, A.R, Berry, A. | | 登録日 | 2010-05-28 | | 公開日 | 2010-09-22 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural Insights Into Substrate Specificity in Variants of N-Acetylneuraminic Acid Lyase Produced by Directed Evolution.
To be Published
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1M8U
 | | Crystal Structure of Bovine gamma-E at 1.65 Ang Resolution | | 分子名称: | gamma-E | | 著者 | Mayer, C, Agueznay, N, Skouri-Panet, F, Prat, K, Putilina, T, Biarrotte-Sorin, S, Tardieu, A. | | 登録日 | 2002-07-26 | | 公開日 | 2003-08-05 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Crystal Structure of Bovine gamma-E
To be Published
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3D75
 | | Crystal structure of a pheromone binding protein mutant D35N, from Apis mellifera, at pH 5.5 | | 分子名称: | N-BUTYL-BENZENESULFONAMIDE, Pheromone-binding protein ASP1 | | 著者 | Pesenti, M.E, Spinelli, S, Bezirard, V, Briand, L, Pernollet, J.C, Tegoni, M, Cambillau, C. | | 登録日 | 2008-05-20 | | 公開日 | 2009-05-26 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Queen bee pheromone binding protein pH-induced domain swapping favors pheromone release
J.Mol.Biol., 390, 2009
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1TRE
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1M7G
 | | Crystal structure of APS kinase from Penicillium Chrysogenum: Ternary structure with ADP and APS | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE-2',3'-VANADATE, ADENOSINE-5'-PHOSPHOSULFATE, ... | | 著者 | Lansdon, E.B, Segel, I.H, Fisher, A.J. | | 登録日 | 2002-07-19 | | 公開日 | 2002-11-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | Ligand-Induced Structural Changes in Adenosine 5'-Phosphosulfate
Kinase from Penicillium chrysogenum.
Biochemistry, 41, 2002
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3QEZ
 | | Crystal structure of the mutant T159V,V182A of orotidine 5'-monophosphate decarboxylase from Methanobacterium thermoautotrophicum complexed with the inhibitor BMP | | 分子名称: | 6-HYDROXYURIDINE-5'-PHOSPHATE, GLYCEROL, Orotidine 5'-phosphate decarboxylase | | 著者 | Fedorov, A.A, Fedorov, E.V, Desai, B, Gerlt, J.A, Almo, S.C. | | 登録日 | 2011-01-20 | | 公開日 | 2012-01-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.5431 Å) | | 主引用文献 | Conformational changes in orotidine 5'-monophosphate decarboxylase: a structure-based explanation for how the 5'-phosphate group activates the enzyme.
Biochemistry, 51, 2012
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2JR4
 | | NMR Solution Structure of the Anticodon of E.coli TRNA-VAL3 With no Modifications | | 分子名称: | 5'-R(*CP*CP*UP*CP*CP*CP*UP*UP*AP*CP*AP*AP*GP*GP*AP*GP*G)-3' | | 著者 | Vendeix, F.A.P, Dziergowska, A, Gustilo, E.M, Graham, W.D, Sproat, B, Malkiewicz, A, Agris, P.F. | | 登録日 | 2007-06-20 | | 公開日 | 2007-07-24 | | 最終更新日 | 2024-05-29 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Anticodon domain modifications contribute order to tRNA for ribosome-mediated codon binding.
Biochemistry, 47, 2008
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2JVV
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