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3EAW
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Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
分子名称: 1,2-ETHANEDIOL, SULFATE ION, Thymidylate synthase
著者Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
登録日2008-08-26
公開日2010-03-02
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.86 Å)
主引用文献Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3E5V
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Crystal Structure Analysis of eqFP611 Double Mutant T122R, N143S
分子名称: Red fluorescent protein eqFP611
著者Nar, H, Nienhaus, K, Nienhaus, U, Wiedenmann, J.
登録日2008-08-14
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Trans-cis isomerization is responsible for the red-shifted fluorescence in variants of the red fluorescent protein eqFP611.
J.Am.Chem.Soc., 130, 2008
3E61
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Crystal structure of a putative transcriptional repressor of ribose operon from Staphylococcus saprophyticus subsp. saprophyticus
分子名称: GLYCEROL, Putative transcriptional repressor of ribose operon
著者Bonanno, J.B, Freeman, J, Bain, K.T, Chang, S, Romero, R, Smith, D, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-08-14
公開日2008-08-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a putative transcriptional repressor of ribose operon from Staphylococcus saprophyticus subsp. saprophyticus
To be Published
3E6Q
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BU of 3e6q by Molmil
Putative 5-carboxymethyl-2-hydroxymuconate isomerase from Pseudomonas aeruginosa.
分子名称: 1,2-ETHANEDIOL, ACETATE ION, FORMIC ACID, ...
著者Osipiuk, J, Xu, X, Cui, H, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-08-15
公開日2008-08-26
最終更新日2020-05-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献X-ray crystal structure of putative 5-carboxymethyl-2-hydroxymuconate isomerase from Pseudomonas aeruginosa.
To be Published
3E7J
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BU of 3e7j by Molmil
HeparinaseII H202A/Y257A double mutant complexed with a heparan sulfate tetrasaccharide substrate
分子名称: 4-deoxy-alpha-L-threo-hex-4-enopyranuronic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-alpha-D-glucopyranuronic acid-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, Heparinase II protein, ...
著者Shaya, D, Cygler, M.
登録日2008-08-18
公開日2008-12-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Catalytic mechanism of heparinase II investigated by site-directed mutagenesis and the crystal structure with its substrate.
J.Biol.Chem., 285, 2010
3E8C
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Crystal structures of the kinase domain of PKA in complex with ATP-competitive inhibitors
分子名称: 4-[2-(4-amino-1,2,5-oxadiazol-3-yl)-6-{[(2R)-2-amino-3-phenylpropyl]oxy}-1-ethyl-1H-imidazo[4,5-c]pyridin-4-yl]-2-methylbut-3-yn-2-ol, cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor peptide
著者Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P.
登録日2008-08-19
公開日2008-11-18
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Aminofurazans as potent inhibitors of AKT kinase
Bioorg.Med.Chem.Lett., 19, 2009
4O2T
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Crystal structure of a DUF4827 family protein (BDI_1692) from Parabacteroides distasonis ATCC 8503 at 2.40 A resolution
分子名称: Uncharacterized protein
著者Joint Center for Structural Genomics (JCSG)
登録日2013-12-17
公開日2014-02-26
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structure of a hypothetical protein (BDI_1692) from Parabacteroides distasonis ATCC 8503 at 2.40 A resolution
To be published
4JRL
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Crystal structure of a putative glycoside hydrolase (BACOVA_00087) from Bacteroides ovatus ATCC 8483 at 2.10 A resolution
分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2013-03-21
公開日2013-04-24
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Crystal structure of a putative glycoside hydrolase (BACOVA_00087) from Bacteroides ovatus ATCC 8483 at 2.10 A resolution
To be published
3ED1
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Crystal Structure of Rice GID1 complexed with GA3
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, GIBBERELLIN A3, Gibberellin receptor GID1, ...
著者Shimada, A, Nakatsu, T, Ueguchi-Tanaka, M, Kato, H, Matsuoka, M.
登録日2008-09-02
公開日2008-11-25
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis for gibberellin recognition by its receptor GID1.
Nature, 456, 2008
3EEZ
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Crystal structure of a putative mandelate racemase/muconate lactonizing enzyme from Silicibacter pomeroyi
分子名称: putative Mandelate racemase/muconate lactonizing enzyme
著者Bonanno, J.B, Rutter, M, Bain, K.T, Hu, S, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-09-07
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of a putative mandelate racemase/muconate lactonizing enzyme from Silicibacter pomeroyi
To be Published
3EMU
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BU of 3emu by Molmil
Crystal structure of a leucine rich repeat and phosphatase domain containing protein from Entamoeba histolytica
分子名称: SULFATE ION, leucine rich repeat and phosphatase domain containing protein
著者Bonanno, J.B, Gilmore, M, Bain, K.T, Hu, S, Ozyurt, S, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-09-25
公開日2008-10-14
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a leucine rich repeat and phosphatase domain containing protein from Entamoeba histolytica
To be Published
3EHG
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BU of 3ehg by Molmil
Crystal structure of the ATP-binding domain of DesK in complex with ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, IODIDE ION, MAGNESIUM ION, ...
著者Trajtenberg, F, Buschiazzo, A.
登録日2008-09-12
公開日2009-09-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Structural and enzymatic insights into the ATP binding and autophosphorylation mechanism of a sensor histidine kinase
J.Biol.Chem., 285, 2010
3ENS
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BU of 3ens by Molmil
Crystal structure of human FXA in complex with methyl (2Z)-3-[(3-chloro-1H-indol-7-yl)amino]-2-cyano-3-{[(3S)-2-oxo-1-(2-oxo-2-pyrrolidin-1-ylethyl)azepan-3-yl]amino}acrylate
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Activated factor Xa heavy chain, ...
著者Klei, H.E.
登録日2008-09-25
公開日2008-12-30
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Design, Structure-Activity Relationships, X-ray Crystal Structure, and Energetic Contributions of a Critical P1 Pharmacophore: 3-Chloroindole-7-yl-Based Factor Xa Inhibitors.
J.Med.Chem., 51, 2008
3ELM
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BU of 3elm by Molmil
Crystal Structure of MMP-13 Complexed with Inhibitor 24f
分子名称: (2R)-({[5-(4-ethoxyphenyl)thiophen-2-yl]sulfonyl}amino){1-[(1-methylethoxy)carbonyl]piperidin-4-yl}ethanoic acid, CALCIUM ION, Collagenase 3, ...
著者Kulathila, R, Monovich, L, Koehn, J.
登録日2008-09-22
公開日2009-07-21
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Discovery of potent, selective, and orally active carboxylic acid based inhibitors of matrix metalloproteinase-13
J.Med.Chem., 52, 2009
3EM6
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Crystal structure of I50L/A71V mutant of hiv-1 protease in complex with inhibitor darunavir
分子名称: (3R,3AS,6AR)-HEXAHYDROFURO[2,3-B]FURAN-3-YL(1S,2R)-3-[[(4-AMINOPHENYL)SULFONYL](ISOBUTYL)AMINO]-1-BENZYL-2-HYDROXYPROPYLCARBAMATE, ACETATE ION, PHOSPHATE ION, ...
著者Royer, C.J, King, N.M, Prabu-Jeyabalan, M, Ng, C, Nalivaika, E.A, Schiffer, C.A.
登録日2008-09-23
公開日2009-09-01
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Kinetic and structural studies on atazanavir specific I50L drug-resistant HIV-1 protease mutant.
To be Published
4JRF
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BU of 4jrf by Molmil
Crystal structure of a putative cell adhesion protein (BACOVA_01548) from Bacteroides ovatus ATCC 8483 at 1.98 A resolution (PSI Community Target, Nakayama)
分子名称: CALCIUM ION, CHLORIDE ION, SULFATE ION, ...
著者Joint Center for Structural Genomics (JCSG)
登録日2013-03-21
公開日2013-04-03
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献A Distinct Type of Pilus from the Human Microbiome.
Cell, 165, 2016
3E87
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Crystal structures of the kinase domain of AKT2 in complex with ATP-competitive inhibitors
分子名称: Glycogen synthase kinase-3 beta peptide, N-[(1S)-2-amino-1-phenylethyl]-5-(1H-pyrrolo[2,3-b]pyridin-4-yl)thiophene-2-carboxamide, RAC-beta serine/threonine-protein kinase
著者Concha, N.O, Elkins, P.A, Smallwood, A, Ward, P.
登録日2008-08-19
公開日2008-10-14
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Aminofurazans as potent inhibitors of AKT kinase
Bioorg.Med.Chem.Lett., 19, 2009
4JM1
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Crystal structure of a protein with alpha-lytic protease prodomain-like fold (BDI_0842) from Parabacteroides distasonis ATCC 8503 at 1.40 A resolution
分子名称: 1,2-ETHANEDIOL, hypothetical protein
著者Joint Center for Structural Genomics (JCSG)
登録日2013-03-13
公開日2013-04-03
最終更新日2023-02-01
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Crystal structure of a hypothetical protein (BDI_0842) from Parabacteroides distasonis ATCC 8503 at 1.40 A resolution
To be published
3E8X
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Putative NAD-dependent epimerase/dehydratase from Bacillus halodurans.
分子名称: CHLORIDE ION, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Putative NAD-dependent epimerase/dehydratase
著者Osipiuk, J, Skarina, T, Onopriyenko, O, Savchenko, A, Edwards, A.M, Joachimiak, A, Midwest Center for Structural Genomics (MCSG)
登録日2008-08-20
公開日2008-09-02
最終更新日2017-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献X-ray crystal structure of putative NAD-dependent epimerase/dehydratase from Bacillus halodurans.
To be Published
3EBV
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Crystal structure of putative Chitinase A from Streptomyces coelicolor.
分子名称: Chinitase A, SULFATE ION
著者Vigdorovich, V, Ramagopal, U.A, Toro, R, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-08-28
公開日2008-09-30
最終更新日2021-02-10
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Crystal structure of putative Chitinase A from Streptomyces coelicolor
To be Published
3EJF
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Crystal structure of IBV X-domain at pH 8.5
分子名称: Non-structural protein 3
著者Piotrowski, Y, Hansen, G, Hilgenfeld, R.
登録日2008-09-18
公開日2008-09-30
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structures of the X-domains of a Group-1 and a Group-3 coronavirus reveal that ADP-ribose-binding may not be a conserved property.
Protein Sci., 18, 2009
3EJL
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Replacement of Val3 in Human Thymidylate Synthase Affects Its Kinetic Properties and Intracellular Stability
分子名称: 5-FLUORO-2'-DEOXYURIDINE-5'-MONOPHOSPHATE, PHOSPHATE ION, Thymidylate synthase
著者Huang, X, Gibson, L.M, Bell, B.J, Lovelace, L.L, Pena, M.M, Berger, F.G, Berger, S.H.
登録日2008-09-18
公開日2010-03-02
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Replacement of Val3 in human thymidylate synthase affects its kinetic properties and intracellular stability .
Biochemistry, 49, 2010
3EL2
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Crystal Structure of Monomeric Actin Bound to Ca-ATP
分子名称: ADENOSINE-5'-TRIPHOSPHATE, Actin-5C, CALCIUM ION
著者Nair, U.B, Joel, P.B, Wan, Q, Lowey, S, Rould, M.A, Trybus, K.M.
登録日2008-09-19
公開日2008-10-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal structures of monomeric actin bound to cytochalasin D.
J.Mol.Biol., 384, 2008
3EEQ
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Crystal structure of a putative cobalamin biosynthesis protein G homolog from Sulfolobus solfataricus
分子名称: SULFATE ION, putative Cobalamin biosynthesis protein G homolog
著者Bonanno, J.B, Gilmore, M, Bain, K.T, Chang, S, Romero, R, Wasserman, S, Sauder, J.M, Burley, S.K, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-09-05
公開日2008-09-30
最終更新日2021-02-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a putative cobalamin biosynthesis protein G homolog from Sulfolobus solfataricus
To be Published
3EP9
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Human AdoMetDC with no putrescine bound
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, PYRUVIC ACID, S-adenosylmethionine decarboxylase alpha chain, ...
著者Bale, S, Lopez, M.M, Makhatadze, G.I, Fang, Q, Pegg, A.E, Ealick, S.E.
登録日2008-09-29
公開日2008-12-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structural Basis for Putrescine Activation of Human S-Adenosylmethionine Decarboxylase.
Biochemistry, 47, 2008

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