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7WV3
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Toll-like receptor3 linear cluster
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, RNA (80-MER), ...
著者Lim, C.S, Jang, Y.H, Lee, G.Y, Han, G.M, Lee, J.O.
登録日2022-02-09
公開日2022-11-16
最終更新日2022-12-07
実験手法ELECTRON MICROSCOPY (2.26 Å)
主引用文献TLR3 forms a highly organized cluster when bound to a poly(I:C) RNA ligand.
Nat Commun, 13, 2022
7EI3
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Crystal structure of MasL, a thiolase from Massilia sp. YMA4
分子名称: Acetyl-CoA C-acyltransferase
著者Lin, C.C, Huang, K.F, Yang, Y.L.
登録日2021-03-30
公開日2022-04-06
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors.
Commun Biol, 5, 2022
1B5M
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RAT OUTER MITOCHONDRIAL MEMBRANE CYTOCHROME B5
分子名称: CYTOCHROME B5, PROTOPORPHYRIN IX CONTAINING FE
著者Rivera, M, White, S.P, Zhang, X.
登録日1996-11-07
公開日1997-03-12
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献13C NMR spectroscopic and X-ray crystallographic study of the role played by mitochondrial cytochrome b5 heme propionates in the electrostatic binding to cytochrome c.
Biochemistry, 35, 1996
8IEB
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Cryo-EM structure of GPR156 of GPR156-miniGo-scFv16 complex (local refine)
分子名称: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate
著者Shin, J, Park, J, Cho, Y.
登録日2023-02-15
公開日2024-02-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (3.03 Å)
主引用文献Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
8IEI
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Cryo-EM structure of GPR156A/B of G-protein free GPR156 (local refine)
分子名称: Probable G-protein coupled receptor 156, [(2R)-3-[(E)-hexadec-9-enoyl]oxy-2-octadecanoyloxy-propyl] 2-(trimethylazaniumyl)ethyl phosphate
著者Shin, J, Park, J, Cho, Y.
登録日2023-02-15
公開日2024-02-14
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.62 Å)
主引用文献Constitutive activation mechanism of a class C GPCR.
Nat.Struct.Mol.Biol., 31, 2024
1CMU
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THE ROLE OF ASPARTATE-235 IN THE BINDING OF CATIONS TO AN ARTIFICIAL CAVITY AT THE RADICAL SITE OF CYTOCHROME C PEROXIDASE
分子名称: CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
著者Fitzgerald, M.M, Trester, M.L, Jensen, G.M, Mcree, D.E, Goodin, D.B.
登録日1995-04-10
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of aspartate-235 in the binding of cations to an artificial cavity at the radical site of cytochrome c peroxidase.
Protein Sci., 4, 1995
3HK5
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Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinarate
分子名称: CARBONATE ION, CHLORIDE ION, D-arabinaric acid, ...
著者Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C.
登録日2009-05-22
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.
Biochemistry, 48, 2009
3HK8
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Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Arabinohydroxamate
分子名称: CARBONATE ION, CHLORIDE ION, D-arabinohydroxamic acid, ...
著者Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C.
登録日2009-05-22
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.
Biochemistry, 48, 2009
3HKA
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Crystal structure of uronate isomerase from Bacillus halodurans complexed with zinc and D-Fructuronate
分子名称: CARBONATE ION, CHLORIDE ION, D-fructuronic acid, ...
著者Fedorov, A.A, Fedorov, E.V, Nguyen, T.T, Raushel, F.M, Almo, S.C.
登録日2009-05-22
公開日2009-08-25
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The mechanism of the reaction catalyzed by uronate isomerase illustrates how an isomerase may have evolved from a hydrolase within the amidohydrolase superfamily.
Biochemistry, 48, 2009
5MYK
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BU of 5myk by Molmil
Structure of Pyroglutamate-Abeta-specific Fab c#17 in complex with murine Abeta-pE3-18PEGb
分子名称: Amyloid beta A4 protein, Fab c#17 heavy chain, Fab c#17 light chain
著者Parthier, C, Piechotta, A, Stubbs, M.T.
登録日2017-01-26
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural and functional analyses of pyroglutamate-amyloid-beta-specific antibodies as a basis for Alzheimer immunotherapy.
J. Biol. Chem., 292, 2017
5W27
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Crystal structure of TnmS3 in complex with tiancimycin (TNM B)
分子名称: Glyoxalase/bleomycin resisance protein/dioxygenase, methyl (2E)-3-[(1aS,11S,11aS,14Z,18R)-3,18-dihydroxy-4,9-dioxo-4,9,10,11-tetrahydro-11aH-11,1a-hept[3]ene[1,5]diynonaphtho[2,3-h]oxireno[c]quinolin-11a-yl]but-2-enoate
著者Chang, C.Y, Chang, C, Nocek, B, Rudolf, J.D, Joachimiak, A, Phillips Jr, G.N, SHen, B, Enzyme Discovery for Natural Product Biosynthesis (NatPro), Midwest Center for Structural Genomics (MCSG)
登録日2017-06-05
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Crystal structure of TnmS3 in complex with tiancimycin (TNM B)
To Be Published
1CMT
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BU of 1cmt by Molmil
THE ROLE OF ASPARTATE-235 IN THE BINDING OF CATIONS TO AN ARTIFICIAL CAVITY AT THE RADICAL SITE OF CYTOCHROME C PEROXIDASE
分子名称: CYTOCHROME C PEROXIDASE, PROTOPORPHYRIN IX CONTAINING FE
著者Fitzgerald, M.M, Trester, M.L, Jensen, G.M, Mcree, D.E, Goodin, D.B.
登録日1995-04-11
公開日1995-07-10
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献The role of aspartate-235 in the binding of cations to an artificial cavity at the radical site of cytochrome c peroxidase.
Protein Sci., 4, 1995
1UN9
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BU of 1un9 by Molmil
Crystal structure of the dihydroxyacetone kinase from C. freundii in complex with AMP-PNP and Mg2+
分子名称: DIHYDROXYACETONE, DIHYDROXYACETONE KINASE, MAGNESIUM ION, ...
著者Siebold, C, Arnold, I, Garcia-Alles, L.F, Baumann, U, Erni, B.
登録日2003-09-08
公開日2003-10-30
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal Structure of the Citrobacter Freundii Dihydroxyacetone Kinase Reveals an Eight-Stranded Alpha-Helical Barrel ATP-Binding Domain
J.Biol.Chem., 278, 2003
1UNS
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BU of 1uns by Molmil
IDENTIFICATION OF A SECONDARY ZINC-BINDING SITE IN STAPHYLOCOCCAL ENTEROTOXIN C2: IMPLICATIONS FOR SUPERANTIGEN RECOGNITION
分子名称: ENTEROTOXIN TYPE C-2, ZINC ION
著者Papageorgiou, A.C, Baker, M.D, McLeod, J.D, Goda, S, Sansom, D.M, Tranter, H.S, Acharya, K.R.
登録日2003-09-15
公開日2003-11-13
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Identification of a Secondary Zinc-Binding Site in Staphylococcal Enterotoxin C2: Implications for Superantigen Recognition
J.Biol.Chem., 279, 2004
7BY0
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BU of 7by0 by Molmil
The cryo-EM structure of CENP-A nucleosome in complex with the phosphorylated CENP-C
分子名称: DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ...
著者Ariyoshi, M, Makino, F, Fukagawa, T.
登録日2020-04-21
公開日2021-02-10
最終更新日2021-03-10
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-EM structure of the CENP-A nucleosome in complex with phosphorylated CENP-C.
Embo J., 40, 2021
7BXT
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BU of 7bxt by Molmil
The cryo-EM structure of CENP-A nucleosome in complex with CENP-C peptide and CENP-N N-terminal domain
分子名称: CENP-C, DNA (145-mer), Histone H2A type 1-B/E, ...
著者Ariyoshi, M, Makino, F, Fukagawa, T.
登録日2020-04-20
公開日2021-02-10
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structure of the CENP-A nucleosome in complex with phosphorylated CENP-C.
Embo J., 40, 2021
1V9M
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BU of 1v9m by Molmil
Crystal structure of the C subunit of V-type ATPase from Thermus thermophilus
分子名称: GLYCEROL, V-type ATP synthase subunit C
著者Numoto, N, Kita, A, Miki, K, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2004-01-26
公開日2004-05-04
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure of the C subunit of V-type ATPase from Thermus thermophilus at 1.85 A resolution.
Acta Crystallogr.,Sect.D, 60, 2004
4C37
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PKA-S6K1 Chimera with compound 21a (CCT196539) bound
分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(6-bromo-1-ethyl-1H-imidazo[4,5-c]pyridin-2-yl)-1,2,5-oxadiazol-3-amine, CAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT ALPHA, ...
著者Couty, S, Westwood, I.M, Kalusa, A, Cano, C, Travers, J, Boxall, K, Chow, C.L, Burns, S, Schmitt, J, Pickard, L, Barillari, C, McAndrew, P.C, Clarke, P.A, Linardopoulos, S, Griffin, R.J, Aherne, G.W, Raynaud, F.I, Workman, P, Jones, K, van Montfort, R.L.M.
登録日2013-08-21
公開日2013-10-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The discovery of potent ribosomal S6 kinase inhibitors by high-throughput screening and structure-guided drug design.
Oncotarget, 4, 2013
6PIX
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BU of 6pix by Molmil
Crystal structure of HCV NS3/4A D168A protease in complex with P4-P5-5 (WK-25)
分子名称: 1,2-ETHANEDIOL, NS3/4A protease, SULFATE ION, ...
著者Zephyr, J, Schiffer, C.A.
登録日2019-06-27
公開日2020-03-04
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Avoiding Drug Resistance by Substrate Envelope-Guided Design: Toward Potent and Robust HCV NS3/4A Protease Inhibitors.
Mbio, 11, 2020
5MSN
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BU of 5msn by Molmil
Structure of the Dcc1 Protein
分子名称: DCC1 protein
著者Wade, B.O, Singleton, M.R.
登録日2017-01-05
公開日2017-02-15
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.002 Å)
主引用文献Structural studies of RFC(C)(tf18) reveal a novel chromatin recruitment role for Dcc1.
EMBO Rep., 18, 2017
3AG2
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Bovine Heart Cytochrome c Oxidase in the Carbon Monoxide-bound Fully Reduced State at 100 K
分子名称: (1R)-2-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-1-[(PALMITOYLOXY)METHYL]ETHYL (11E)-OCTADEC-11-ENOATE, (1S)-2-{[(2-AMINOETHOXY)(HYDROXY)PHOSPHORYL]OXY}-1-[(STEAROYLOXY)METHYL]ETHYL (5E,8E,11E,14E)-ICOSA-5,8,11,14-TETRAENOATE, (7R,17E,20E)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSA-17,20-DIEN-1-AMINIUM 4-OXIDE, ...
著者Muramoto, K, Ohta, K, Shinzawa-Itoh, K, Kanda, K, Taniguchi, M, Nabekura, H, Yamashita, E, Tsukihara, T, Yoshikawa, S.
登録日2010-03-19
公開日2010-04-28
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献Bovine cytochrome c oxidase structures enable O2 reduction with minimization of reactive oxygens and provide a proton-pumping gate
Proc.Natl.Acad.Sci.USA, 107, 2010
8S94
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Structure of C-terminal domains of Walker B mutated MCM8/9 heterohexamer complex with ADP
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA helicase MCM8, DNA helicase MCM9, ...
著者Li, C, Gao, Y.
登録日2023-03-27
公開日2023-06-07
最終更新日2023-08-23
実験手法ELECTRON MICROSCOPY (3.94 Å)
主引用文献Activity, substrate preference and structure of the HsMCM8/9 helicase.
Nucleic Acids Res., 51, 2023
8PFA
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X-ray structure of the Thermus thermophilus K167R mutant of the PilF-GSPIIB domain in the c-di-GMP bound state
分子名称: 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), ACETATE ION, SULFATE ION, ...
著者Neissner, K, Woehnert, J.
登録日2023-06-15
公開日2024-06-26
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献X-ray structure of the Thermus thermophilus K167R mutant of the PilF-GSPIIB domain in the c-di-GMP bound state
To Be Published
5K65
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Crystal structure of VEGF binding IgG1-Fc (Fcab CT6)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)-[alpha-D-mannopyranose-(1-3)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, Ig gamma-1 chain C region, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
著者Humm, A, Lobner, E, Kitzmuller, M, Mlynek, G, Obinger, C, Djinovic-Carugo, K.
登録日2016-05-24
公開日2017-09-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Two-faced Fcab prevents polymerization with VEGF and reveals thermodynamics and the 2.15 angstrom crystal structure of the complex.
MAbs, 9, 2017
5MSM
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Structure of the Dcc1-Ctf8-Ctf18C Trimer
分子名称: Chromosome transmission fidelity protein 18, Chromosome transmission fidelity protein 8, Sister chromatid cohesion protein DCC1
著者Wade, B.O, Singleton, M.R.
登録日2017-01-05
公開日2017-02-15
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.29 Å)
主引用文献Structural studies of RFC(C)(tf18) reveal a novel chromatin recruitment role for Dcc1.
EMBO Rep., 18, 2017

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