PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

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6F2B	Crystal structure of the complex Fe(II)/alpha-ketoglutarate dependent dioxygenase KDO1 with Fe(II)/alpha-ketoglutarate 分子名称: 2-OXOGLUTARIC ACID, FE (II) ION, L-lysine 3-hydroxylase 著者 Isabet, T, Stura, E.A, Legrand, P, Zaparucha, A, Bastard, K. 登録日 2017-11-24 公開日 2018-11-14 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structural Studies based on two Lysine Dioxygenases with Distinct Regioselectivity Brings Insights Into Enzyme Specificity within the Clavaminate Synthase-Like Family. Sci Rep, 8, 2018
7O55	Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2231 分子名称: Inhibitor MI-2231, Serine protease NS3, Serine protease subunit NS2B 著者 Huber, S, Heine, A, Steinmetzer, T. 登録日 2021-04-07 公開日 2022-04-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. J.Med.Chem., 65, 2022
4LNN	B. subtilis glutamine synthetase structures reveal large active site conformational changes and basis for isoenzyme specific regulation: structure of apo form of GS 分子名称: Glutamine synthetase, MAGNESIUM ION, SULFATE ION 著者 Schumacher, M.A, Chinnam, N, Tonthat, N, Fisher, S, Wray, L. 登録日 2013-07-11 公開日 2013-11-13 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Structures of the Bacillus subtilis Glutamine Synthetase Dodecamer Reveal Large Intersubunit Catalytic Conformational Changes Linked to a Unique Feedback Inhibition Mechanism. J.Biol.Chem., 288, 2013
7OBV	Crystal Structure of Unlinked NS2B-NS3 Protease from Zika Virus in Complex with Inhibitor MI-2248 分子名称: Inhibitor MI-2248, Serine protease NS3, Serine protease subunit NS2B 著者 Huber, S, Heine, A, Steinmetzer, T. 登録日 2021-04-23 公開日 2022-04-06 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 Structure-Based Optimization and Characterization of Macrocyclic Zika Virus NS2B-NS3 Protease Inhibitors. J.Med.Chem., 65, 2022
8RST	Rap from bacteriophage Phi3T in presence of pheromone SRGHTS 分子名称: Glycerol ethoxylate, Rap3T, SRGHTS, ... 著者 Felipe-Ruiz, A, Zamora-Caballero, S, Marina, A. 登録日 2024-01-25 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.56 Å) 主引用文献 Extracellular proteolysis of tandemly duplicated pheromone propeptides affords additional complexity to bacterial quorum sensing Plos Biol., 2024
4LHQ	Ricin A chain bound to camelid nanobody (VHH8) 分子名称: Camelid nanobody, Ricin 著者 Rudolph, M.J, Cheung, J, Franklin, M, Burshteyn, F, Cassidy, M, Gary, E, Mantis, N. 登録日 2013-07-01 公開日 2014-06-11 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal Structures of Ricin Toxin's Enzymatic Subunit (RTA) in Complex with Neutralizing and Non-Neutralizing Single-Chain Antibodies. J.Mol.Biol., 426, 2014
7O0Y	ABC transporter NosDFY, nucleotide-free in GDN 分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... 著者 Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. 登録日 2021-03-28 公開日 2022-04-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.3 Å) 主引用文献 Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
8FE7	Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide (SMG9) and UDP-GlcNAc 分子名称: Nonsense-mediated mRNA decay factor SMG9, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE 著者 Xie, J, Jiang, J. 登録日 2022-12-05 公開日 2023-08-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.98 Å) 主引用文献 Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase. Nat.Chem.Biol., 19, 2023
7O15	ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 2 分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... 著者 Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. 登録日 2021-03-28 公開日 2022-04-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY 主引用文献 Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
8FE6	Crystal structure of human O-GlcNAc transferase (OGT) in complex with an exosite-binding peptide and UDP-GlcNAc 分子名称: A motif peptide, UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit, URIDINE-DIPHOSPHATE-N-ACETYLGLUCOSAMINE 著者 Xie, J, Jiang, J. 登録日 2022-12-05 公開日 2023-08-09 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (3.06 Å) 主引用文献 Motif-dependent binding on the intervening domain regulates O-GlcNAc transferase. Nat.Chem.Biol., 19, 2023
8FNJ	Structure of E138K/G140A HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.4 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
7O04	Crystal structure of a shortened IpgC variant in complex with [(2-chloro-5-nitrophenyl)methyl](methyl)amine 分子名称: 1-(2-chloro-5-nitrophenyl)-N-methylmethanamine, CHLORIDE ION, Chaperone protein IpgC, ... 著者 Gardonyi, M, Heine, A, Klebe, G. 登録日 2021-03-25 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.74 Å) 主引用文献 Crystal structure of a shortened IpgC variant in complex with [(2-chloro-5-nitrophenyl)methyl](methyl)amine To be published
8FNN	Structure of E138K/G140A/Q148K HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.7 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
6F4G	'Crystal structure of the Drosophila melanogaster SNF/U2A'/U2-SL4 complex 分子名称: CHLORIDE ION, Probable U2 small nuclear ribonucleoprotein A', SULFATE ION, ... 著者 Weber, G, DeKoster, G, Holton, N, Hall, K.B, Wahl, M.C. 登録日 2017-11-29 公開日 2018-06-20 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Molecular principles underlying dual RNA specificity in the Drosophila SNF protein. Nat Commun, 9, 2018
4MKJ	Crystal structure of L-methionine gamma-lyase from Citrobacter freundii modified by allicine 分子名称: Methionine gamma-lyase, PENTAETHYLENE GLYCOL, SODIUM ION, ... 著者 Revtovich, S.V, Nikulin, A.D, Morozova, E.A, Zakomirdina, L.N, Demidkina, T.V. 登録日 2013-09-05 公開日 2014-11-12 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.849 Å) 主引用文献 Alliin is a suicide substrate of Citrobacter freundii methionine gamma-lyase: structural bases of inactivation of the enzyme. Acta Crystallogr.,Sect.D, 70, 2014
7O16	ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 3 分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... 著者 Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. 登録日 2021-03-28 公開日 2022-04-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY 主引用文献 Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
8RSV	Rap from bacteriophage Phi3T in presence of pheromone RRGHTAS 分子名称: Glycerol ethoxylate, Pheromone RRGHTAS, Rap3T 著者 Felipe-Ruiz, A, Zamora-Caballero, S, Marina, A. 登録日 2024-01-25 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.19 Å) 主引用文献 Extracellular proteolysis of tandemly duplicated pheromone propeptides affords additional complexity to bacterial quorum sensing Plos Biol., 2024
7O14	ABC transporter NosDFY, nucleotide-free in lipid nanodisc, R-domain 1 分子名称: MAGNESIUM ION, Probable ABC transporter ATP-binding protein NosF, Probable ABC transporter binding protein NosD, ... 著者 Mueller, C, Zhang, L, Lu, W, Einsle, O, Du, J. 登録日 2021-03-28 公開日 2022-04-13 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY 主引用文献 Molecular interplay of an assembly machinery for nitrous oxide reductase. Nature, 608, 2022
8FN7	Structure of WT HIV-1 intasome bound to Dolutegravir 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
7O7M	(h-alpha2M)4 native II 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Alpha-2-macroglobulin, ... 著者 Luque, D, Goulas, T, Mata, C.P, Mendes, S.R, Gomis-Ruth, F.X, Caston, J.R. 登録日 2021-04-13 公開日 2022-04-13 最終更新日 2022-05-11 実験手法 ELECTRON MICROSCOPY (6.6 Å) 主引用文献 Cryo-EM structures show the mechanistic basis of pan-peptidase inhibition by human alpha 2 -macroglobulin. Proc.Natl.Acad.Sci.USA, 119, 2022
6F2R	A heterotetramer of human HspB2 and HspB3 分子名称: Heat shock protein beta-2, Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-3,Heat shock protein beta-2, HspB2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2,Heat shock protein beta-2, ... 著者 Clark, A.R, Cole, A.R, Boelens, W.C, Keep, N.H, Slingsby, C. 登録日 2017-11-27 公開日 2018-07-25 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (3.9 Å) 主引用文献 Terminal Regions Confer Plasticity to the Tetrameric Assembly of Human HspB2 and HspB3. J.Mol.Biol., 430, 2018
8FNL	Structure of E138K/Q148K HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (2.8 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023
8RSU	Rap from bacteriophage Phi3T in presence of pheromone RRGHTA 分子名称: Glycerol ethoxylate, Pheromone RRGHTA, Rap3T 著者 Felipe-Ruiz, A, Zamora-Caballero, S, Marina, A. 登録日 2024-01-25 公開日 2024-07-24 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Extracellular proteolysis of tandemly duplicated pheromone propeptides affords additional complexity to bacterial quorum sensing Plos Biol., 2024
7NYS	monomeric acetyl-CoA synthase in closed conformation with carbon monoxide bound to the Ni proximal of cluster A 分子名称: $l^{3}-oxidanylidynemethylnickel, 2-[3,8,8,12,12-pentakis(2-hydroxy-2-oxoethyl)-2,7,11-tris(oxidanylidene)-1,4,6,9,10,13-hexaoxa-5$l^{6}-titanaspiro[4.4^{5}.4^{5}]tridecan-3-yl]ethanoic acid, CHLORIDE ION, ... 著者 Kreibich, J, Jeoung, J.H, Dobbek, H. 登録日 2021-03-23 公開日 2022-04-13 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Ligand binding at the Ni,Ni-[4Fe-4S] cluster of acetyl-CoA synthase To Be Published
8FND	Structure of E138K HIV-1 intasome with Dolutegravir bound 分子名称: (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, DNA (25-MER), DNA (27-MER), ... 著者 Shan, Z.L, Passos, D.O, Strutzenberg, T.S, Li, M, Lyumkis, D. 登録日 2022-12-27 公開日 2023-08-09 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Sci Adv, 9, 2023

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