PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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2XAH	Crystal structure of LSD1-CoREST in complex with (+)-trans-2- phenylcyclopropyl-1-amine 分子名称: 3-PHENYLPROPANAL, FLAVIN-ADENINE DINUCLEOTIDE, LYSINE-SPECIFIC HISTONE DEMETHYLASE 1, ... 著者 Binda, C, Valente, S, Romanenghi, M, Pilotto, S, Cirilli, R, Karytinos, A, Ciossani, G, Botrugno, O.A, Forneris, F, Tardugno, M, Edmondson, D.E, Minucci, S, Mattevi, A, Mai, A. 登録日 2010-03-31 公開日 2010-05-05 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Biochemical, Structural, and Biological Evaluation of Tranylcypromine Derivatives as Inhibitors of Histone Demethylases Lsd1 and Lsd2. J.Am.Chem.Soc., 132, 2010
1FOI	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH 1400W(H4B-FREE) 分子名称: ACETATE ION, CACODYLATE ION, GLYCEROL, ... 著者 Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L. 登録日 2000-08-28 公開日 2001-07-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors. Biochemistry, 40, 2001
1FOP	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-BOUND) 分子名称: 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ARGININE, ... 著者 Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L. 登録日 2000-08-28 公開日 2001-07-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors. Biochemistry, 40, 2001
3CF4	Structure of the CODH component of the M. barkeri ACDS complex 分子名称: ACETIC ACID, Acetyl-CoA decarboxylase/synthase alpha subunit, Acetyl-CoA decarboxylase/synthase epsilon subunit, ... 著者 Gong, W, Hao, B, Wei, Z, Ferguson Jr, D.J, Tallant, T, Krzycki, J.A, Chan, M.K. 登録日 2008-03-01 公開日 2008-07-22 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structure of the alpha2 epsilon2 Ni-dependent CO dehydrogenase component of the Methanosarcina barkeri acetyl-CoA decarboxylase/synthase complex Proc.Natl.Acad.Sci.USA, 105, 2008
2Y37	The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (iNOS) 分子名称: 2-[(1R)-3-amino-1-phenyl-propoxy]-4-chloro-benzonitrile, 5,6,7,8-TETRAHYDROBIOPTERIN, GLYCEROL, ... 著者 Cheshire, D.R, Andrews, G, Beaton, H.G, Birkinshaw, T.N, Boughton-Smith, N, Connolly, S, Cook, T.R, Cooper, A, Cooper, S.L, Cox, D, Dixon, J, Gensmantel, N, Hamley, P.J, Harrison, R, Hartopp, P, Kack, H, Luker, T, Mete, A, Millichip, I, Nicholls, D.J, Pimm, A.D, St-Gallay, S.A, Wallace, A.V. 登録日 2010-12-19 公開日 2011-04-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (Inos). Bioorg.Med.Chem.Lett., 21, 2011
4GRT	HUMAN GLUTATHIONE REDUCTASE A34E, R37W MUTANT, MIXED DISULFIDE BETWEEN TRYPANOTHIONE AND THE ENZYME 分子名称: BIS(GAMMA-GLUTAMYL-CYSTEINYL-GLYCINYL)SPERMIDINE, FLAVIN-ADENINE DINUCLEOTIDE, GLUTATHIONE REDUCTASE 著者 Stoll, V.S, Simpson, S.J, Krauth-Siegel, R.L, Walsh, C.T, Pai, E.F. 登録日 1997-02-12 公開日 1997-08-12 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Glutathione reductase turned into trypanothione reductase: structural analysis of an engineered change in substrate specificity. Biochemistry, 36, 1997
1SEZ	Crystal Structure of Protoporphyrinogen IX Oxidase 分子名称: 2-{2-[4-(1,1,3,3-TETRAMETHYLBUTYL)PHENOXY]ETHOXY}ETHANOL, 4-BROMO-3-(5'-CARBOXY-4'-CHLORO-2'-FLUOROPHENYL)-1-METHYL-5-TRIFLUOROMETHYL-PYRAZOL, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Koch, M, Breithaupt, C, Kiefersauer, R, Freigang, J, Huber, R, Messerschmidt, A. 登録日 2004-02-19 公開日 2004-04-13 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Crystal structure of protoporphyrinogen IX oxidase: a key enzyme in haem and chlorophyll biosynthesis. Embo J., 23, 2004
1GVE	Aflatoxin aldehyde reductase (AKR7A1) from Rat Liver 分子名称: AFLATOXIN B1 ALDEHYDE REDUCTASE MEMBER 3, CITRIC ACID, GLYCEROL, ... 著者 Kozma, E, Brown, E, Ellis, E.M, Lapthorn, A.J. 登録日 2002-02-08 公開日 2002-06-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 The Crystal Structure of Rat Liver Akr7A1: A Dimeric Member of the Aldo-Keto Reductase Superfamily J.Biol.Chem., 277, 2002
2BZ9	Ligand-free structure of sterol 14alpha-demethylase from Mycobacterium tuberculosis in P2(1) space group 分子名称: PROTOPORPHYRIN IX CONTAINING FE, STEROL 14ALPHA-DEMETHYLASE 著者 Yermalitskaya, L.V, Waterman, M.R, Podust, L.M. 登録日 2005-08-12 公開日 2006-12-07 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.21 Å) 主引用文献 Small Molecule Scaffolds for Cyp51 Inhibitors Identified by High Throughput Screening and Defined by X-Ray Crystallography Antimicrob.Agents Chemother., 51, 2007
1FOO	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH L-ARG AND NO(H4B-FREE) 分子名称: ACETATE ION, ARGININE, CACODYLATE ION, ... 著者 Raman, C.S, Li, H, Martasek, P, Masters, B.S.S, Poulos, T.L. 登録日 2000-08-28 公開日 2001-07-20 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystallographic studies on endothelial nitric oxide synthase complexed with nitric oxide and mechanism-based inhibitors. Biochemistry, 40, 2001
5T61	TUNGSTEN-CONTAINING FORMYLMETHANOFURAN DEHYDROGENASE FROM METHANOTHERMOBACTER WOLFEII, TRICLINIC FORM AT 2.55 A 分子名称: 2-AMINO-5,6-DIMERCAPTO-7-METHYL-3,7,8A,9-TETRAHYDRO-8-OXA-1,3,9,10-TETRAAZA-ANTHRACEN-4-ONE GUANOSINE DINUCLEOTIDE, CHLORIDE ION, HYDROSULFURIC ACID, ... 著者 Wagner, T, Ermler, U, Shima, S. 登録日 2016-09-01 公開日 2016-10-19 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 The methanogenic CO2 reducing-and-fixing enzyme is bifunctional and contains 46 [4Fe-4S] clusters. Science, 354, 2016
2Y34	S-nitrosylated PHD2 (NO exposed) in complex with Fe(II) and UN9 分子名称: EGL NINE HOMOLOG 1, FE (II) ION, N-[(1-CHLORO-4-HYDROXYISOQUINOLIN-3-YL)CARBONYL]GLYCINE 著者 Chowdhury, R, McDonough, M.A, Schofield, C.J. 登録日 2010-12-18 公開日 2010-12-29 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2.01 Å) 主引用文献 Studies on the reaction of nitric oxide with the hypoxia-inducible factor prolyl hydroxylase domain 2 (EGLN1). J. Mol. Biol., 410, 2011
7CZL	Structural insights into a dimeric Psb27-photosystem II complex from a cyanobacterium Thermosynechococcus vulcanus 分子名称: (1S)-2-(ALPHA-L-ALLOPYRANOSYLOXY)-1-[(TRIDECANOYLOXY)METHYL]ETHYL PALMITATE, 1,2-DI-O-ACYL-3-O-[6-DEOXY-6-SULFO-ALPHA-D-GLUCOPYRANOSYL]-SN-GLYCEROL, 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, ... 著者 Pi, X, Huang, G, Xiao, Y. 登録日 2020-09-09 公開日 2021-01-20 最終更新日 2025-06-25 実験手法 ELECTRON MICROSCOPY (3.78 Å) 主引用文献 Structural insights into a dimeric Psb27-photosystem II complex from a cyanobacterium Thermosynechococcus vulcanus . Proc.Natl.Acad.Sci.USA, 118, 2021
3IQZ	Structure of F420 dependent methylene-tetrahydromethanopterin dehydrogenase in complex with methylene-tetrahydromethanopterin 分子名称: 5,10-DIMETHYLENE TETRAHYDROMETHANOPTERIN, CALCIUM ION, F420-dependent methylenetetrahydromethanopterin dehydrogenase, ... 著者 Ceh, K.E, Demmer, U, Warkentin, E, Moll, J, Thauer, R.K, Shima, S, Ermler, U. 登録日 2009-08-21 公開日 2009-10-06 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural basis of the hydride transfer mechanism in F(420)-dependent methylenetetrahydromethanopterin dehydrogenase Biochemistry, 48, 2009
4IES	Cys-persulfenate bound Cysteine Dioxygenase at pH 6.2 in the presence of Cys 分子名称: Cysteine dioxygenase type 1, FE (III) ION, S-HYDROPEROXYCYSTEINE 著者 Driggers, C.M, Cooley, R.B, Sankaran, B, Karplus, P.A. 登録日 2012-12-13 公開日 2013-06-26 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.4 Å) 主引用文献 Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH. J.Mol.Biol., 425, 2013
2XFN	Human monoamine oxidase B in complex with 2-(2-benzofuranyl)-2- imidazoline 分子名称: 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, Amine oxidase [flavin-containing] B, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. 登録日 2010-05-26 公開日 2010-10-06 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (1.6 Å) 主引用文献 Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
1D1V	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH S-ETHYL-N-PHENYL-ISOTHIOUREA (H4B BOUND) 分子名称: 2-ETHYL-1-PHENYL-ISOTHIOUREA, 5,6,7,8-TETRAHYDROBIOPTERIN, ACETATE ION, ... 著者 Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. 登録日 1999-09-21 公開日 2001-07-25 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (1.93 Å) 主引用文献 Implications for isoform-selective inhibitor design derived from the binding mode of bulky isothioureas to the heme domain of endothelial nitric-oxide synthase. J.Biol.Chem., 276, 2001
2XCG	Tranylcypromine-inhibited human monoamine oxidase B in complex with 2- (2-benzofuranyl)-2-imidazoline 分子名称: 2-(2-BENZOFURANYL)-2-IMIDAZOLINE, 3-PHENYLPROPANAL, Amine oxidase [flavin-containing] B, ... 著者 Bonivento, D, Milczek, E.M, McDonald, G.R, Binda, C, Holt, A, Edmondson, D.E, Mattevi, A. 登録日 2010-04-23 公開日 2010-10-06 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Potentiation of ligand binding through cooperative effects in monoamine oxidase B. J. Biol. Chem., 285, 2010
2XLT	Joint-functions of protein residues and NADP(H) in oxygen-activation by flavin-containing monooxygenase: complex with 3-Acetylpyridine adenine dinucleotide phosphate (APADP) 分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE PHOSPHATE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, ... 著者 Orru, R, Fraaije, M.W, Mattevi, A. 登録日 2010-07-21 公開日 2010-09-15 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Joint functions of protein residues and NADP(H) in oxygen activation by flavin-containing monooxygenase. J. Biol. Chem., 285, 2010
3EJD	Crystal Structure of P450BioI in complex with hexadec-9Z-enoic acid ligated Acyl Carrier Protein 分子名称: Acyl carrier protein, Biotin biosynthesis cytochrome P450-like enzyme, CHLORIDE ION, ... 著者 Cryle, M.J, Schlichting, I. 登録日 2008-09-18 公開日 2008-10-07 最終更新日 2024-10-30 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structural insights from a P450 Carrier Protein complex reveal how specificity is achieved in the P450(BioI) ACP complex. Proc.Natl.Acad.Sci.Usa, 105, 2008
1RRL	Soybean Lipoxygenase (LOX-3) at 93K at 2.0 A resolution 分子名称: FE (II) ION, Seed lipoxygenase-3 著者 Borbulevych, O.Y, Jankun, J, Skrzypczak-Jankun, E. 登録日 2003-12-08 公開日 2004-12-21 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 Effect of crystal freezing and small-molecule binding on internal cavity size in a large protein: X-ray and docking studies of lipoxygenase at ambient and low temperature at 2.0 A resolution. Acta Crystallogr.,Sect.D, 62, 2006
1N8Q	LIPOXYGENASE IN COMPLEX WITH PROTOCATECHUIC ACID 分子名称: 3,4-DIHYDROXYBENZOIC ACID, FE (II) ION, lipoxygenase-3 著者 Borbulevych, O.Y, Jankun, J, Selman, S.H, Skrzypczak-Jankun, E. 登録日 2002-11-21 公開日 2003-06-03 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Lipoxygenase interactions with natural flavonoid, quercetin, reveal a complex with protocatechuic acid in its X-ray structure at 2.1 A resolution. PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
3SX6	Crystal structure of sulfide:quinone oxidoreductase Cys356Ala variant from Acidithiobacillus ferrooxidans complexed with decylubiquinone 分子名称: 2-decyl-5,6-dimethoxy-3-methylcyclohexa-2,5-diene-1,4-dione, DODECYL-BETA-D-MALTOSIDE, FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Cherney, M.M, Zhang, Y, James, M.N.G, Weiner, J.H. 登録日 2011-07-14 公開日 2012-05-16 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (1.7955 Å) 主引用文献 Structure-activity characterization of sulfide:quinone oxidoreductase variants. J.Struct.Biol., 178, 2012
2YQ8	Crystal structure of the SeMet-labeled N-terminal domain and peptide substrate binding domain of alpha subunit of prolyl-4 hydroxylase type I from human. 分子名称: PROLYL 4-HYDROXYLASE SUBUNIT ALPHA-1 著者 Anantharajan, J, Koski, M.K, Wierenga, R.K. 登録日 2012-11-06 公開日 2013-10-09 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2.987 Å) 主引用文献 The Structural Motifs for Substrate Binding and Dimerization of the Alpha Subunit of Collagen Prolyl 4-Hydroxylase Structure, 21, 2013
1G65	Crystal structure of epoxomicin:20s proteasome reveals a molecular basis for selectivity of alpha,beta-epoxyketone proteasome inhibitors 分子名称: EPOXOMICIN (peptide inhibitor), MAGNESIUM ION, Proteasome component C1, ... 著者 Groll, M, Kim, K.B, Kairies, N, Huber, R, Crews, C. 登録日 2000-11-03 公開日 2000-11-27 最終更新日 2024-11-06 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Crystal Structure of Epoxomicin:20S Proteasome reveals a molecular basis for selectivity of alpha,beta-Epoxyketone Proteasome Inhibitors J.Am.Chem.Soc., 122, 2000

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