2BZ9

Ligand-free structure of sterol 14alpha-demethylase from Mycobacterium tuberculosis in P2(1) space group

Summary for 2BZ9

Entry DOI	10.2210/pdb2bz9/pdb
Related	1E9X 1EA1 1H5Z
Descriptor	STEROL 14ALPHA-DEMETHYLASE, PROTOPORPHYRIN IX CONTAINING FE (3 entities in total)
Functional Keywords	sterol 14alpha-demethylase, p450, electron transport, heme, iron, lipid synthesis, metal-binding, monooxygenase
Biological source	MYCOBACTERIUM TUBERCULOSIS
Total number of polymer chains	2
Total formula weight	104187.54
Authors	Yermalitskaya, L.V.,Waterman, M.R.,Podust, L.M. (deposition date: 2005-08-12, release date: 2006-12-07, Last modification date: 2023-12-13)
Primary citation	Podust, L.M.,Von Kries, J.P.,Eddine, A.N.,Kim, Y.,Yermalitskaya, L.V.,Kuehne, R.,Ouellet, H.,Warrier, T.,Altekoster, M.,Lee, J.-S.,Rademann, J.,Oschkinat, H.,Kaufmann, S.H.E.,Waterman, M.R. Small Molecule Scaffolds for Cyp51 Inhibitors Identified by High Throughput Screening and Defined by X-Ray Crystallography Antimicrob.Agents Chemother., 51:3915-, 2007 Cited by PubMed: 17846131 DOI: 10.1128/AAC.00311-07 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.21 Å)

Structure validation