Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0005515 | molecular_function | protein binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008398 | molecular_function | sterol 14-demethylase activity |
| A | 0016125 | biological_process | sterol metabolic process |
| A | 0016126 | biological_process | sterol biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005506 | molecular_function | iron ion binding |
| B | 0005515 | molecular_function | protein binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0008398 | molecular_function | sterol 14-demethylase activity |
| B | 0016125 | biological_process | sterol metabolic process |
| B | 0016126 | biological_process | sterol biosynthetic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| B | 0020037 | molecular_function | heme binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE HEM A1449 |
| Chain | Residue |
| A | GLN72 |
| A | PHE387 |
| A | GLY388 |
| A | HIS392 |
| A | CYS394 |
| A | VAL395 |
| A | PHE399 |
| A | ALA400 |
| A | HOH2054 |
| A | LEU105 |
| A | ALA256 |
| A | GLY257 |
| A | THR260 |
| A | SER261 |
| A | PRO320 |
| A | ARG326 |
| A | PRO386 |
| site_id | AC2 |
| Number of Residues | 21 |
| Details | BINDING SITE FOR RESIDUE HEM B1449 |
| Chain | Residue |
| B | GLN72 |
| B | LEU105 |
| B | ALA256 |
| B | GLY257 |
| B | THR260 |
| B | SER261 |
| B | THR264 |
| B | PRO320 |
| B | LEU324 |
| B | ARG326 |
| B | PRO386 |
| B | PHE387 |
| B | GLY388 |
| B | HIS392 |
| B | CYS394 |
| B | VAL395 |
| B | GLY396 |
| B | HOH2016 |
| B | HOH2068 |
| B | HOH2095 |
| B | HOH2114 |
Functional Information from PROSITE/UniProt
| site_id | PS00086 |
| Number of Residues | 10 |
| Details | CYTOCHROME_P450 Cytochrome P450 cysteine heme-iron ligand signature. FGaGRHRCVG |
| Chain | Residue | Details |
| A | PHE387-GLY396 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | GLN72 | |
| B | HIS392 | |
| A | TYR76 | |
| A | LYS97 | |
| A | ARG326 | |
| A | HIS392 | |
| B | GLN72 | |
| B | TYR76 | |
| B | LYS97 | |
| B | ARG326 | |
| Chain | Residue | Details |
| A | CYS394 | |
| B | CYS394 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1akd |
| Chain | Residue | Details |
| A | HIS259 | |
| A | THR260 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1akd |
| Chain | Residue | Details |
| B | HIS259 | |
| B | THR260 | |
