1E9X
Cytochrome P450 14 alpha-sterol demethylase (CYP51) from Mycobacterium tuberculosis in complex with 4-phenylimidazole
Summary for 1E9X
Entry DOI | 10.2210/pdb1e9x/pdb |
Descriptor | CYTOCHROME P450 51-LIKE RV0764C, PROTOPORPHYRIN IX CONTAINING FE, 4-PHENYL-1H-IMIDAZOLE, ... (4 entities in total) |
Functional Keywords | oxidoreductase, cytochrome p450, 14 alpha-sterol demethylase, azole inhibitors |
Biological source | MYCOBACTERIUM TUBERCULOSIS |
Total number of polymer chains | 1 |
Total formula weight | 52259.99 |
Authors | Podust, L.M.,Poulos, T.L.,Waterman, M.R. (deposition date: 2000-10-30, release date: 2000-11-01, Last modification date: 2024-05-08) |
Primary citation | Podust, L.M.,Poulos, T.L.,Waterman, M.R. Crystal Structure of Cytochrome P450 14Alpha -Sterol Demethylase (Cyp51) from Mycobacterium Tuberculosis in Complex with Azole Inhibitors Proc.Natl.Acad.Sci.USA, 98:3068-, 2001 Cited by PubMed: 11248033DOI: 10.1073/PNAS.061562898 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.1 Å) |
Structure validation
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