PDB: 243083 件ウェブページステータス検索Chemie searchBIRD

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4RKA	Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A347 分子名称: 2-{[5-(naphthalen-1-ylmethyl)-4-oxo-4H-1lambda~4~,3-thiazol-2-yl]amino}benzoic acid, Dihydroorotate dehydrogenase (quinone), mitochondrial, ... 著者 Zhu, L, Ren, X, Zhu, J, Li, H. 登録日 2014-10-12 公開日 2015-11-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.71 Å) 主引用文献 Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A347 TO BE PUBLISHED
1ED5	BOVINE ENDOTHELIAL NITRIC OXIDE SYNTHASE HEME DOMAIN COMPLEXED WITH NNA(H4B FREE) 分子名称: ACETATE ION, CACODYLIC ACID, GLYCEROL, ... 著者 Raman, C.S, Li, H, Martasek, P, Southan, G.J, Masters, B.S.S, Poulos, T.L. 登録日 2000-01-26 公開日 2001-01-31 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of nitric oxide synthase bound to nitro indazole reveals a novel inactivation mechanism. Biochemistry, 40, 2001
5RAQ	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001577a 分子名称: 2-[4-(2-methoxyphenyl)piperazin-1-yl]ethanenitrile, CHLORIDE ION, Lysine-specific demethylase 3B, ... 著者 Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. 登録日 2020-03-16 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.85 Å) 主引用文献 PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
5RAF	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001559a 分子名称: (5~{R})-3,4,4-trimethyl-5-(oxidanylamino)-1,3-thiazolidine-2-thione, CHLORIDE ION, Lysine-specific demethylase 3B, ... 著者 Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. 登録日 2020-03-16 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.62 Å) 主引用文献 PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
5RAU	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with DA000165b 分子名称: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... 著者 Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. 登録日 2020-03-16 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.73 Å) 主引用文献 PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
4FGL	Reduced quinone reductase 2 in complex with chloroquine 分子名称: FLAVIN-ADENINE DINUCLEOTIDE, N4-(7-CHLORO-QUINOLIN-4-YL)-N1,N1-DIETHYL-PENTANE-1,4-DIAMINE, Ribosyldihydronicotinamide dehydrogenase [quinone], ... 著者 Leung, K.K, Shilton, B.H. 登録日 2012-06-04 公開日 2013-03-13 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.2 Å) 主引用文献 Crystal structures of quinone reductase 2 bound to antimalarial drugs reveal conformational change upon reduction J.Biol.Chem., 2013
5RAH	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM010032a 分子名称: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... 著者 Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. 登録日 2020-03-16 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.66 Å) 主引用文献 PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
4FDC	Crystal structure of the E493V mutant of human apoptosis inducing factor (AIF) 分子名称: Apoptosis-inducing factor 1, mitochondrial, FLAVIN-ADENINE DINUCLEOTIDE 著者 Sevrioukova, I.F. 登録日 2012-05-27 公開日 2012-10-17 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Cowchock syndrome is associated with a mutation in apoptosis-inducing factor. Am.J.Hum.Genet., 91, 2012
4JTO	Cysteine bound Cysteine Dioxygenase at pH 8.0 in the presence of Cys and dithionite 分子名称: CYSTEINE, Cysteine dioxygenase type 1, FE (II) ION 著者 Driggers, C.M, Karplus, P.A. 登録日 2013-03-23 公開日 2013-06-26 最終更新日 2024-11-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Cysteine Dioxygenase Structures from pH4 to 9: Consistent Cys-Persulfenate Formation at Intermediate pH and a Cys-Bound Enzyme at Higher pH. J.Mol.Biol., 425, 2013
5FYS	Crystal structure of the catalytic domain of human JARID1B in complex with D-2-hydroxyglutarate 分子名称: (2R)-2-hydroxypentanedioic acid, 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... 著者 Nowak, R, Kopec, J, Johansson, C, Gileadi, C, Kupinska, K, Strain-Damerell, C, Szykowska, A, von Delft, F, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. 登録日 2016-03-09 公開日 2017-03-22 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.89 Å) 主引用文献 Crystal Structure of the Catalytic Domain of Human Jarid1B in Complex with D-2-Hydroxyglutarate To be Published
4RLI	Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048 分子名称: Dihydroorotate dehydrogenase (quinone), mitochondrial, FLAVIN MONONUCLEOTIDE, ... 著者 Zhu, L, Ren, X, Zhu, J, Li, H. 登録日 2014-10-17 公開日 2015-11-04 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of human dihydroorotate dehydrogenase (DHODH) with DH03A048 TO BE PUBLISHED
1OOQ	Nitroreductase from e-coli in complex with the inhibitor dicoumarol 分子名称: BISHYDROXY[2H-1-BENZOPYRAN-2-ONE,1,2-BENZOPYRONE], FLAVIN MONONUCLEOTIDE, Oxygen-insensitive NAD(P)H nitroreductase 著者 Johansson, E, Parkinson, G.N, Denny, W.A, Neidle, S. 登録日 2003-03-04 公開日 2003-04-02 最終更新日 2023-08-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Studies on the Nitroreductase Prodrug-Activating System. Crystal Structures of Complexes with the Inhibitor Dicoumarol and Dinitrobenzamide Prodrugs and of the Enzyme Active Form J.Med.Chem., 46, 2003
1MZZ	Crystal Structure of Mutant (M182T)of Nitrite Reductase 分子名称: COPPER (II) ION, Copper-containing nitrite reductase 著者 Guo, H, Olesen, K, Xue, Y, Shapliegh, J, Sjolin, L. 登録日 2002-10-10 公開日 2004-09-28 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The High resolution Crystal Structures of Nitrite Reductase and its mutant Met182Thr from Rhodobacter Sphaeroides Reveal a Gating Mechanism for the Electron Transfer to the Type 1 Copper Center To be Published
5RAG	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with FM001767a 分子名称: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... 著者 Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. 登録日 2020-03-16 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
5RAN	PanDDA analysis group deposition -- Crystal Structure of JMJD1B in complex with XS039080d 分子名称: CHLORIDE ION, Lysine-specific demethylase 3B, MANGANESE (II) ION, ... 著者 Snee, M, Nowak, R, Johansson, C, Burgess-Brown, N.A, Arrowsmith, C.H, Bountra, C, Edwards, A.M, Oppermann, U. 登録日 2020-03-16 公開日 2020-04-22 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 PanDDA analysis group deposition of Human JMJD1B screened against the DSPL Fragment Library To Be Published
2G1M	Cellular Oxygen Sensing: Crystal Structure of Hypoxia-Inducible Factor Prolyl Hydroxylase (PHD2) 分子名称: Egl nine homolog 1, FE (II) ION, N-[(4-HYDROXY-8-IODOISOQUINOLIN-3-YL)CARBONYL]GLYCINE 著者 Mcdonough, M.A, Schofield, C.J. 登録日 2006-02-14 公開日 2006-06-13 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2). Proc.Natl.Acad.Sci.Usa, 103, 2006
1VXO	METHYLPHOSPHONYLATED ACETYLCHOLINESTERASE (AGED) OBTAINED BY REACTION WITH O-ETHYL-S-[2-[BIS(1-METHYLETHYL)AMINO]ETHYL] METHYLPHOSPHONOTHIOATE (VX) 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, METHYLPHOSPHONIC ACID ESTER GROUP, PROTEIN (ACETYLCHOLINESTERASE) 著者 Millard, C.B, Silman, I, Sussman, J.L. 登録日 1999-04-21 公開日 1999-11-15 最終更新日 2024-10-09 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Reaction Products of Acetylcholinesterase and VX Reveal a Mobile Histidine in the Catalytic Triad J.Am.Chem.Soc., 121, 1999
1EIL	2,3-DIHYDROXYBIPHENYL-1,2-DIOXYGENASE 分子名称: 2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE, FE (III) ION, SULFATE ION 著者 Senda, T. 登録日 2000-02-26 公開日 2001-02-26 最終更新日 2024-02-07 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structures of substrate free and complex forms of reactivated BphC, an extradiol type ring-cleavage dioxygenase. J.Inorg.Biochem., 83, 2001
3W7R	Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097 分子名称: 2,6-dioxo-5-[2-(4-phenylphenyl)ethyl]-1,2,3,6- tetrahydropyrimidine-4-carboxylic acid, ACETATE ION, CHLORIDE ION, ... 著者 Inaoka, D.K, Iida, M, Tabuchi, T, Lee, N, Hashimoto, S, Matsuoka, S, Kuranaga, T, Shiba, T, Sakamoto, K, Suzuki, S, Balogun, E.O, Nara, T, Aoki, T, Inoue, M, Honma, T, Tanaka, A, Harada, S, Kita, K. 登録日 2013-03-06 公開日 2014-03-12 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Structure of Human dihydroorotate dehydrogenase in complex with mii-4-097 To be Published
2BZS	Binding of anti-cancer prodrug CB1954 to the activating enzyme NQO2 revealed by the crystal structure of their complex. 分子名称: 5-(AZIRIDIN-1-YL)-2,4-DINITROBENZAMIDE, FLAVIN-ADENINE DINUCLEOTIDE, NRH DEHYDROGENASE [QUINONE] 2, ... 著者 Abu Khader, M.M, Heap, J.T, De Matteis, C, Kellam, B, Doughty, S.W, Minton, N, Paoli, M. 登録日 2005-08-22 公開日 2005-09-23 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Binding of the Anticancer Prodrug Cb1954 to the Activating Enzyme Nqo2 Revealed by the Crystal Structure of Their Complex. J.Med.Chem., 48, 2005
2BVG	Crystal structure of 6-hydoxy-D-nicotine oxidase from Arthrobacter nicotinovorans. Crystal Form 1 (P21) 分子名称: 6-HYDROXY-D-NICOTINE OXIDASE, FLAVIN-ADENINE DINUCLEOTIDE 著者 Koetter, J.W.A, Schulz, G.E. 登録日 2005-06-28 公開日 2005-08-17 最終更新日 2024-11-13 実験手法 X-RAY DIFFRACTION (3.18 Å) 主引用文献 Crystal Structure of 6-Hydroxy-D-Nicotine Oxidase from Arthrobacter Nicotinovorans. J.Mol.Biol., 352, 2005
1WZD	Crystal Structure Of An Artificial Metalloprotein: Fe(10-CH2CH2COOH-Salophen)/Wild Type Heme oxygenase 分子名称: GLYCEROL, Heme oxygenase, SULFATE ION, ... 著者 Unno, M, Yokoi, N, Ueno, T, Watanabe, Y, Ikeda-Saito, M. 登録日 2005-03-04 公開日 2006-02-21 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.35 Å) 主引用文献 Design of metal cofactors activated by a protein-protein electron transfer system. Proc.Natl.Acad.Sci.Usa, 103, 2006
4HVQ	X-ray crystal structure of FECU reconstituted 3-hydroxyanthranilate-3,4-dioxygenase from cupriavidus metallidurans 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-hydroxyanthranilate 3,4-dioxygenase, FE (II) ION 著者 Liu, F, Chen, L, Liu, A. 登録日 2012-11-06 公開日 2013-11-27 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 An Iron Reservoir to the Catalytic Metal: THE RUBREDOXIN IRON IN AN EXTRADIOL DIOXYGENASE. J.Biol.Chem., 290, 2015
1GPB	GLYCOGEN PHOSPHORYLASE B: DESCRIPTION OF THE PROTEIN STRUCTURE 分子名称: GLYCOGEN PHOSPHORYLASE B, PYRIDOXAL-5'-PHOSPHATE 著者 Johnson, L.N, Acharya, K.R, Stuart, D.I. 登録日 1990-06-04 公開日 1992-10-15 最終更新日 2025-03-26 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Glycogen Phosphorylase B: Description of the Protein Structure Glycogen Phosphorylase B: Description of the Protein Structure, 1991
3RVH	Crystal Structure of JMJD2A Complexed with Inhibitor 分子名称: 8-hydroxy-3-(piperazin-1-yl)quinoline-5-carboxylic acid, GLYCEROL, Lysine-specific demethylase 4A, ... 著者 King, O.N.F, Maloney, D.J, Tumber, A, Rai, G, Jadhav, A, Clifton, I.J, Heightman, T.D, Simeonov, A, McDonough, M.A, Schofield, C.J. 登録日 2011-05-06 公開日 2012-05-09 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.251 Å) 主引用文献 Crystal Structure of JMJD2A Complexed with Inhibitor To be Published

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