PDB: 45118 件ウェブページステータス検索Chemie searchBIRD

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5J2E	Ternary complex crystal structure of DNA polymerase Beta with C:T mismatch at the primer terminus 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, CHLORIDE ION, DNA polymerase beta, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-29 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
7B12	HUMAN IMMUNOPROTEASOME 20S PARTICLE IN COMPLEX WITH [2-(3-ethylphenyl)-1-[(2S)-3-phenyl-2-[(pyrazin-2-yl)formamido]propanamido]ethyl]boronic acid 分子名称: ((R)-2-(3-ethylphenyl)-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)ethyl)boronic acid, Proteasome subunit alpha type-1, Proteasome subunit alpha type-2, ... 著者 Musil, D, Klein, M, Crosignani, S. 登録日 2020-11-23 公開日 2021-12-01 最終更新日 2023-06-14 実験手法 X-RAY DIFFRACTION (2.43 Å) 主引用文献 Structure-Based Optimization and Discovery of M3258, a Specific Inhibitor of the Immunoproteasome Subunit LMP7 ( beta 5i). J.Med.Chem., 64, 2021
8PZY	Intracellular leucine aminopeptidase of Pseudomonas aeruginosa PA14 - hexameric assembly with manganese bound 分子名称: 1,2-ETHANEDIOL, 2-[3-[3-(2-hydroxyethoxy)propoxy]propoxy]ethanol, AMMONIUM ION, ... 著者 Simpson, M.C, Czekster, C.M, Harding, C.J. 登録日 2023-07-27 公開日 2023-11-15 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Unveiling the Catalytic Mechanism of a Processive Metalloaminopeptidase. Biochemistry, 62, 2023
5J0Q	Binary complex crystal structure of DNA polymerase Beta with A:G mismatch at the primer terminus 分子名称: DNA polymerase beta, Downstream Primer Strand, Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-28 公開日 2016-10-26 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J2I	Ternary complex crystal structure of DNA polymerase Beta with T:C mismatch at the primer terminus 分子名称: 2'-DEOXYURIDINE 5'-ALPHA,BETA-IMIDO-TRIPHOSPHATE, DNA polymerase beta, Downstream Primer Strand, ... 著者 Batra, V.K, Wilson, S.H. 登録日 2016-03-29 公開日 2016-10-26 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of DNA Polymerase Mispaired DNA Termini Transitioning to Pre-catalytic Complexes Support an Induced-Fit Fidelity Mechanism. Structure, 24, 2016
5J48	PKG I's Carboyl Terminal Cyclic Nucleotide Binding Domain (CNB-B) in a complex with 8-pCPT-cGMP 分子名称: 1,2-ETHANEDIOL, 2-amino-8-[(4-chlorophenyl)sulfanyl]-9-[(2S,4aR,6R,7R,7aS)-2,7-dihydroxy-2-oxotetrahydro-2H,4H-2lambda~5~-furo[3,2-d][1,3,2]dioxaphosphinin-6-yl]-3,9-dihydro-6H-purin-6-one, CALCIUM ION, ... 著者 Campbell, J.C, Sankaran, B, Kim, C.W. 登録日 2016-03-31 公開日 2017-04-12 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.49 Å) 主引用文献 Structural Basis of Analog Specificity in PKG I and II. ACS Chem. Biol., 12, 2017
5J5P	AMP-PNP-stabilized ATPase domain of topoisomerase IV from Streptococcus pneumoniae, complex type I 分子名称: DNA (5'-D(*GP*CP*GP*CP*GP*C)-3'), DNA topoisomerase 4 subunit B, MAGNESIUM ION, ... 著者 Laponogov, I, Pan, X.-S, Skamrova, G, Umrekar, T, Fisher, L.M, Sanderson, M.R. 登録日 2016-04-03 公開日 2017-07-26 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Trapping of the transport-segment DNA by the ATPase domains of a type II topoisomerase. Nat Commun, 9, 2018
4FW6	Crystal Structure of the LpxC in complex with N-[(2S,3R)-3-HYDROXY-1-(HYDROXYAMINO)-1-OXOBUTAN-2-YL]-4-(PHENYLETHYNYL)BENZAMIDE inhibitor 分子名称: ACETATE ION, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... 著者 Kang, Y.N, Stuckey, J.A. 登録日 2012-06-29 公開日 2013-05-15 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.83 Å) 主引用文献 Crystal Structure of the LpxC to be published
5IU9	Crystal Structure of Zebrafish Protocadherin-19 EC1-4 分子名称: CALCIUM ION, Protocadherin-19 isoform 1, SODIUM ION 著者 Cooper, S.R, Jontes, J.D, Sotomayor, M. 登録日 2016-03-17 公開日 2016-11-02 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (3.59 Å) 主引用文献 Structural determinants of adhesion by Protocadherin-19 and implications for its role in epilepsy. Elife, 5, 2016
5J4H	Structure of humanised RadA-mutant humRadA22F in complex with indole-6-carboxylic acid 分子名称: 1H-indole-6-carboxylic acid, CALCIUM ION, DIMETHYL SULFOXIDE, ... 著者 Fischer, G, Marsh, M, Moschetti, T, Sharpe, T, Scott, D, Morgan, M, Ng, H, Skidmore, J, Venkitaraman, A, Abell, C, Blundell, T.L, Hyvonen, M. 登録日 2016-04-01 公開日 2016-10-19 最終更新日 2024-05-01 実験手法 X-RAY DIFFRACTION (1.374 Å) 主引用文献 Engineering Archeal Surrogate Systems for the Development of Protein-Protein Interaction Inhibitors against Human RAD51. J.Mol.Biol., 428, 2016
8QAY	Medicago truncatula HISN5 (IGPD) in complex with MN, FMT, ACT, CIT, EDO, SO4 分子名称: 1,2-ETHANEDIOL, ACETATE ION, CITRIC ACID, ... 著者 Witek, W, Ruszkowski, M. 登録日 2023-08-23 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting. Front Plant Sci, 15, 2024
8QAW	Medicago truncatula HISN5 (IGPD) in complex with MN, IMD, EDO, FMT, GOL and TRS 分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ... 著者 Witek, W, Ruszkowski, M. 登録日 2023-08-23 公開日 2024-04-10 実験手法 X-RAY DIFFRACTION (1.55 Å) 主引用文献 Targeting imidazole-glycerol phosphate dehydratase in plants: novel approach for structural and functional studies, and inhibitor blueprinting. Front Plant Sci, 15, 2024
7A5J	Structure of the split human mitoribosomal large subunit with P-and E-site mt-tRNAs 分子名称: 16S rRNA, 39S ribosomal protein L10, mitochondrial, ... 著者 Desai, N, Yang, H, Chandrasekaran, V, Kazi, R, Minczuk, M, Ramakrishnan, V. 登録日 2020-08-21 公開日 2020-12-23 最終更新日 2023-03-15 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 Elongational stalling activates mitoribosome-associated quality control. Science, 370, 2020
8PW7	A respirasome from murine liver 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Vercellino, I, Sazanov, L.A. 登録日 2023-07-19 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 SCAF1 drives the compositional diversity of mammalian respirasomes. Nat.Struct.Mol.Biol., 2024
5HHH	Structure of human DNA polymerase beta Host-Guest complexed with the control G for N7-CBZ-platination 分子名称: DNA (5'-D(*CP*CP*GP*AP*CP*GP*GP*AP*GP*GP*AP*GP*CP*AP*GP*G)-3'), DNA (5'-D(P*CP*CP*TP*GP*CP*TP*CP*CP*TP*C)-3'), DNA (5'-D(P*GP*TP*CP*GP*G)-3'), ... 著者 Koag, M.-C, Lee, S. 登録日 2016-01-11 公開日 2017-01-18 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.363 Å) 主引用文献 Synthesis, structure, and biological evaluation of a platinum-carbazole conjugate. Chem Biol Drug Des, 91, 2018
4E3R	PLP-bound aminotransferase mutant crystal structure from Vibrio fluvialis 分子名称: Pyruvate transaminase, SODIUM ION, SULFATE ION 著者 Midelfort, K.S, Kumar, R, Han, S, Karmilowicz, M.J, McConnell, K, Gehlhaar, D.K, Mistry, A, Chang, J.S, Anderson, M, Vilalobos, A, Minshull, J, Govindarajan, S, Wong, J.W. 登録日 2012-03-10 公開日 2012-10-10 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Redesigning and characterizing the substrate specificity and activity of Vibrio fluvialis aminotransferase for the synthesis of imagabalin. Protein Eng.Des.Sel., 26, 2013
8PW5	CS respirasome from murine liver 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ... 著者 Vercellino, I, Sazanov, L.A. 登録日 2023-07-19 公開日 2024-04-24 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 SCAF1 drives the compositional diversity of mammalian respirasomes. Nat.Struct.Mol.Biol., 2024
5HSX	Crystal Structure of a Putative Alpha-ketoglutarate-dependent Taurine Dioxygenase from Burkholderia xenovorans 分子名称: 1,2-ETHANEDIOL, GLYCEROL, Putative alpha-ketoglutarate-dependent taurine dioxygenase, ... 著者 Seattle Structural Genomics Center for Infectious Disease (SSGCID) 登録日 2016-01-26 公開日 2016-02-10 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal Structure of a Putative Alpha-ketoglutarate-dependent Taurine Dioxygenase from Burkholderia xenovorans to be published
7B4L	CryoEM structure of the human sodium proton exchanger NHA2 分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, SODIUM ION, Sodium/hydrogen exchanger 9B2, ... 著者 Woehlert, D, Kuhlbrandt, W, Yildiz, O. 登録日 2020-12-02 公開日 2022-01-12 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 CryoEM structure of the human sodium proton exchanger NHA2 To Be Published
5IMV	Xanthomonas campestris Peroxiredoxin Q - Structure F6 分子名称: Bacterioferritin comigratory protein, FORMIC ACID, SODIUM ION 著者 Perkins, A, Parsonage, D, Nelson, K.J, Poole, L.B, Karplus, A. 登録日 2016-03-07 公開日 2016-09-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.05 Å) 主引用文献 Peroxiredoxin Catalysis at Atomic Resolution. Structure, 24, 2016
7ANY	Structure of the Laspartomycin C Friulimicin-like mutant in complex with Geranyl phosphate 分子名称: CADMIUM ION, CALCIUM ION, CHLORIDE ION, ... 著者 Zeronian, M.R, Pearce, N.M, Lutz, M, Wood, T.M, Martin, N.I, Janssen, B.J.C. 登録日 2020-10-13 公開日 2022-02-02 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.135 Å) 主引用文献 Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures Chem Sci, 13, 2022
8OUD	Structure of the human neutral amino acid transporter ASCT2 in complex with nanobody 469 分子名称: ALANINE, CHOLESTEROL HEMISUCCINATE, Nanobody 469, ... 著者 Canul-Tec, J, Reyes, N. 登録日 2023-04-22 公開日 2024-05-01 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (2.31 Å) 主引用文献 Receptor-recognition and antiviral mechanisms of retrovirus-derived human proteins. Nat.Struct.Mol.Biol., 2024
7B6A	BK Polyomavirus VP1 pentamer core (residues 30-299) 分子名称: CALCIUM ION, DIMETHYL SULFOXIDE, IODIDE ION, ... 著者 Osipov, E.M, Munawar, A, Beelen, S, Strelkov, S.V. 登録日 2020-12-07 公開日 2022-06-22 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.44 Å) 主引用文献 Discovery of novel druggable pockets on polyomavirus VP1 through crystallographic fragment-based screening to develop capsid assembly inhibitors. Rsc Chem Biol, 3, 2022
5JDS	Crystal structure of PD-L1 complexed with a nanobody at 1.7 Angstron resolution 分子名称: CHLORIDE ION, Nanobody, Programmed cell death 1 ligand 1, ... 著者 Zhou, A, Wei, H. 登録日 2016-04-17 公開日 2017-04-12 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural basis of a novel PD-L1 nanobody for immune checkpoint blockade. Cell Discov, 3, 2017
8OVE	CRYO-EM STRUCTURE OF TRYPANOSOMA BRUCEI PROCYCLIC FORM 80S RIBOSOME : TB11CS6H1 snoRNA mutant 分子名称: 40S ribosomal protein L14, putative, 40S ribosomal protein S10, ... 著者 Rajan, K.S, Yonath, A. 登録日 2023-04-25 公開日 2023-11-29 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.6 Å) 主引用文献 A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei. Nat Commun, 14, 2023

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