PDB: 46188 件ウェブページステータス検索Chemie searchBIRD

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4ND3	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (l-lactic acid) and cofactor (b-nicotinamide adenine dinucleotide) 分子名称: (2S)-2-HYDROXYPROPANOIC ACID, GLYCEROL, Lactate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
4QDH	Crystal Structure of the C-terminal Domain of Mouse TLR9 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, SULFATE ION, Variable lymphocyte receptor B, ... 著者 Collins, B.C, Wilson, I.A. 登録日 2014-05-13 公開日 2014-06-11 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.399 Å) 主引用文献 Crystal structure of the C-terminal domain of mouse TLR9. Proteins, 82, 2014
6FVE	Macrophage Migration Inhibitory Factor (MIF) with Covalently Bound FITC 分子名称: 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)-5-[(E)-(sulfanylmethylidene)amino]benzoic acid, Macrophage migration inhibitory factor, SULFATE ION 著者 Samygina, V.R, Bourenkov, G, Sokolov, A.V. 登録日 2018-03-02 公開日 2018-06-06 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.41 Å) 主引用文献 Structural Study of the Complex Formed by Ceruloplasmin and Macrophage Migration Inhibitory Factor. Biochemistry Mosc., 83, 2018
7CWE	Human Fructose-1,6-bisphosphatase 1 in APO R-state 分子名称: Fructose-1,6-bisphosphatase 1, MAGNESIUM ION 著者 Chen, Y, Zhang, J, Li, C, Cao, Y. 登録日 2020-08-28 公開日 2021-09-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Human Fructose-1,6-bisphosphatase 1 in APO R-state To Be Published
7CVH	Human Fructose-1,6-bisphosphatase 1 in complex with geranylgeranyl diphosphate 分子名称: 1,6-di-O-phosphono-beta-D-fructofuranose, ADENOSINE MONOPHOSPHATE, Fructose-1,6-bisphosphatase 1, ... 著者 Chen, Y, Zhang, J, Li, C, Cao, Y. 登録日 2020-08-26 公開日 2021-09-08 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.09 Å) 主引用文献 The structural basis for GGPP activation on the enzymatic activities FBP1 To Be Published
6N7O	Crystal structure of GIL01 gp7 分子名称: GIL01 gp7, IODIDE ION 著者 Caveney, N.A, Strynadka, N.C.J. 登録日 2018-11-27 公開日 2019-05-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Structural Insights into Bacteriophage GIL01 gp7 Inhibition of Host LexA Repressor. Structure, 27, 2019
6G2I	Filament of acetyl-CoA carboxylase and BRCT domains of BRCA1 (ACC-BRCT) at 5.9 A resolution 分子名称: Acetyl-CoA carboxylase 1, Breast cancer type 1 susceptibility protein 著者 Hunkeler, M, Hagmann, A, Stuttfeld, E, Chami, M, Stahlberg, H, Maier, T. 登録日 2018-03-23 公開日 2018-06-13 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis for regulation of human acetyl-CoA carboxylase. Nature, 558, 2018
4QBO	VRR_NUC domain 分子名称: MAGNESIUM ION, Nuclease 著者 Smerdon, S.J, Pennell, S, Li, J. 登録日 2014-05-08 公開日 2014-09-10 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.3 Å) 主引用文献 FAN1 activity on asymmetric repair intermediates is mediated by an atypical monomeric virus-type replication-repair nuclease domain. Cell Rep, 8, 2014
6J5S	Crystal structure of human HINT1 mutant complexing with AP5A 分子名称: BIS(ADENOSINE)-5'-PENTAPHOSPHATE, ETHANESULFONIC ACID, Histidine triad nucleotide-binding protein 1 著者 Wang, J, Fang, P, Guo, M. 登録日 2019-01-11 公開日 2019-09-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.02 Å) 主引用文献 Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells. Nat Commun, 10, 2019
4NXJ	Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum 分子名称: Bromodomain protein 著者 Wernimont, A.K, Loppnau, P, Knapp, S, Fonseca, M, Brennan, P.E, Dong, A, Walker, J.R, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Hui, R, Hutchinson, A, Structural Genomics Consortium (SGC) 登録日 2013-12-09 公開日 2014-03-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Crystal Structure of PF3D7_1475600, a bromodomain from Plasmodium Falciparum TO BE PUBLISHED
4ND1	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with cofactor (b-nicotinamide adenine dinucleotide) and inhibitor (oxamic acid) 分子名称: GLYCEROL, Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
6LRI	Human cGAS catalytic domain bound with compound 17 分子名称: 3-[5-(2-hydroxy-2-oxoethyl)-3-oxidanylidene-[1,2,4]triazino[2,3-a]benzimidazol-2-yl]propanoic acid, Cyclic GMP-AMP synthase, ZINC ION 著者 Zhao, W.F, Xiong, M.Y, Yuan, X.J, Sun, H.B, Xu, Y.C. 登録日 2020-01-16 公開日 2020-06-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing. J.Chem.Inf.Model., 60, 2020
4ND2	Crystal structure of the lactate dehydrogenase from cryptosporidium parvum complexed with substrate (pyruvic acid) and cofactor analog (3-acetylpyridine adenine dinucleotide) 分子名称: 3-ACETYLPYRIDINE ADENINE DINUCLEOTIDE, GLYCEROL, Lactate dehydrogenase, ... 著者 Chattopadhyay, D, Cook, W.J. 登録日 2013-10-25 公開日 2014-12-17 最終更新日 2024-10-16 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Biochemical and structural characterization of Cryptosporidium parvum Lactate dehydrogenase. Int.J.Biol.Macromol., 74C, 2014
6J53	Crystal structure of human HINT1 complexing with ATP 分子名称: ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1 著者 Wang, J, Fang, P, Guo, M. 登録日 2019-01-10 公開日 2019-09-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells. Nat Commun, 10, 2019
6J58	Crystal structure of human HINT1 complexing with AP4A 分子名称: ADENOSINE MONOPHOSPHATE, Histidine triad nucleotide-binding protein 1 著者 Wang, J, Fang, P, Guo, M. 登録日 2019-01-10 公開日 2019-09-25 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.521 Å) 主引用文献 Second messenger Ap4A polymerizes target protein HINT1 to transduce signals in Fc epsilon RI-activated mast cells. Nat Commun, 10, 2019
6FNA	Mono- and bivalent 14-3-3 inhibitors for characterizing supramolecular lysine-PEG interactions in proteins 分子名称: 14-3-3 protein zeta/delta, BENZOIC ACID, CALCIUM ION, ... 著者 Bier, D, Ottmann, C. 登録日 2018-02-02 公開日 2018-07-04 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Mono- and Bivalent 14-3-3 Inhibitors for Characterizing Supramolecular "Lysine Wrapping" of Oligoethylene Glycol (OEG) Moieties in Proteins. Chemistry, 24, 2018
1X7J	CRYSTAL STRUCTURE OF ESTROGEN RECEPTOR BETA COMPLEXED WITH GENISTEIN 分子名称: Estrogen receptor beta, GENISTEIN, STEROID RECEPTOR COACTIVATOR-1 著者 Manas, E.S, Xu, Z.B, Unwalla, R.J, Somers, W.S. 登録日 2004-08-14 公開日 2005-03-01 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Understanding the Selectivity of Genistein for Human Estrogen Receptor-Beta Using X-Ray Crystallography and Computational Methods Structure, 12, 2004
5D1C	Crystal structure of D233G-Y306F HDAC8 in complex with a tetrapeptide substrate 分子名称: GLYCEROL, HDAC8 Fluor de Lys tetrapeptide substrate, Histone deacetylase 8, ... 著者 Decroos, C, Christianson, N.H, Gullett, L.E, Bowman, C.M, Christianson, K.E, Deardorff, M.A, Christianson, D.W. 登録日 2015-08-04 公開日 2015-10-21 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (1.422 Å) 主引用文献 Biochemical and Structural Characterization of HDAC8 Mutants Associated with Cornelia de Lange Syndrome Spectrum Disorders. Biochemistry, 54, 2015
6HA6	Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPV3 (220-246) 分子名称: GLYCEROL, Hypoxia-inducible factor 1-alpha inhibitor, N-OXALYLGLYCINE, ... 著者 Leissing, T.M, Clifton, I.J, Saward, B.G, Lu, X, Hopkinson, R.J, Schofield, C.J. 登録日 2018-08-07 公開日 2019-08-28 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.98 Å) 主引用文献 Factor Inhibiting HIF (FIH) in complex with zinc, NOG and TRPV3 (220-246) To Be Published
8CHF	cryo-EM Structure of Craf:14-3-3:Mek1 分子名称: 14-3-3 protein zeta isoform X1, 2-{4-[(1E)-1-(hydroxyimino)-2,3-dihydro-1H-inden-5-yl]-3-(pyridin-4-yl)-1H-pyrazol-1-yl}ethanol, Dual specificity mitogen-activated protein kinase kinase 1, ... 著者 Dedden, D, Ulrich, G. 登録日 2023-02-07 公開日 2024-02-21 最終更新日 2024-02-28 実験手法 ELECTRON MICROSCOPY (4.25 Å) 主引用文献 Cryo-EM Structures of CRAF 2 /14-3-3 2 and CRAF 2 /14-3-3 2 /MEK1 2 Complexes. J.Mol.Biol., 436, 2024
6LRE	Human cGAS catalytic domain bound with compound 3 分子名称: 1,3-bis(oxidanylidene)benzo[de]isoquinoline-6,7-dicarboxylic acid, Cyclic GMP-AMP synthase, ZINC ION 著者 Zhao, W.F, Xiong, M.Y, Yuan, X.J, Sun, H.B, Xu, Y.C. 登録日 2020-01-16 公開日 2020-06-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.65 Å) 主引用文献 In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing. J.Chem.Inf.Model., 60, 2020
6LRK	Human cGAS catalytic domain bound with compound 40 分子名称: (3R)-1-pyrrolo[1,2-a]quinoxalin-4-ylpiperidine-3-carboxylic acid, Cyclic GMP-AMP synthase, ZINC ION 著者 Zhao, W.F, Xiong, M.Y, Yuan, X.J, Sun, H.B, Xu, Y.C. 登録日 2020-01-16 公開日 2020-06-24 最終更新日 2023-11-29 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 In Silico Screening-Based Discovery of Novel Inhibitors of Human Cyclic GMP-AMP Synthase: A Cross-Validation Study of Molecular Docking and Experimental Testing. J.Chem.Inf.Model., 60, 2020
4ME9	Crystal structure of a transcriptional regulator, TetR family (BCE_2991) from Bacillus cereus ATCC 10987 at 2.50 A resolution 分子名称: CHLORIDE ION, PHOSPHATE ION, Transcriptional regulator, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2013-08-25 公開日 2013-09-25 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of a transcriptional regulator, TetR family (BCE_2991) from Bacillus cereus ATCC 10987 at 2.50 A resolution To be published
6HI4	The ATAD2 bromodomain in complex with compound 7 分子名称: (2~{R})-2-azanyl-~{N}-[4-ethanoyl-5-(3-methoxyphenyl)-1,3-thiazol-2-yl]propanamide, ATPase family AAA domain-containing protein 2, SULFATE ION 著者 Sledz, P, Caflisch, A. 登録日 2018-08-29 公開日 2019-02-20 最終更新日 2024-01-17 実験手法 X-RAY DIFFRACTION (1.69 Å) 主引用文献 Hitting a Moving Target: Simulation and Crystallography Study of ATAD2 Bromodomain Blockers. Acs Med.Chem.Lett., 11, 2020
5DBK	apo form of the quorum sensor NprR from B. thuringiensis 分子名称: Transcriptional regulator/TPR domain protein 著者 Talagas, A, Perchat, S, Lereclus, D, Nessler, S. 登録日 2015-08-21 公開日 2016-07-13 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (3.241 Å) 主引用文献 How Quorum Sensing Connects Sporulation to Necrotrophism in Bacillus thuringiensis. Plos Pathog., 12, 2016

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