PDB: 47120 件ウェブページステータス検索Chemie searchBIRD

---

8QVG	Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. 分子名称: Bifunctional epoxide hydrolase 2, N-(3,3-DIPHENYLPROPYL)PYRROLIDINE-1-CARBOXAMIDE 著者 Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. 登録日 2023-10-18 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Exploring serial crystallography for drug discovery. Iucrj, 2024
7NN4	Crystal structure of Mycobacterium tuberculosis ArgD with prosthetic group pyridoxal 5'-phosphate and 3-hydroxy-2-naphthoic acid. 分子名称: 3-hydroxynaphthalene-2-carboxylic acid, Acetylornithine aminotransferase, NITRATE ION 著者 Gupta, P, Mendes, V, Blundell, T.L. 登録日 2021-02-24 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
8QRV	ASCT2 protomer in lipid nanodiscs under low Na+ concentration in the outward-facing state (OFS) 分子名称: Neutral amino acid transporter B(0), SODIUM ION 著者 Borowska, A, Rheinberger, J, Paulino, C, Slotboom, D.J. 登録日 2023-10-09 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (2.9 Å) 主引用文献 Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2. Nat Commun, 15, 2024
8QH9	X-ray structure of Danio rerio histone deacetylase 6 (HDAC6) CD2 in complex with a S-29b 分子名称: 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, Histone deacetylase 6, ... 著者 Barinka, C, Motlova, L. 登録日 2023-09-07 公開日 2024-08-07 実験手法 X-RAY DIFFRACTION (1.59 Å) 主引用文献 Biological and structural investigation of tetrahydro-beta-carboline-based selective HDAC6 inhibitors with improved stability. Eur.J.Med.Chem., 276, 2024
7NN1	Crystal structure of Mycobacterium tuberculosis ArgD with prosthetic group pyridoxal 5'-phosphate 分子名称: Acetylornithine aminotransferase, NITRATE ION 著者 Gupta, P, Mendes, V, Blundell, T.L. 登録日 2021-02-24 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.54 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
4K2Z	Crystal structure of the complex of type I Ribosome inactivating protein from Momordica balsamina with Methylethylamine at 1.80 A resolution 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, METHYLETHYLAMINE, ... 著者 Yamini, S, Pandey, S, Kushwaha, G.S, Sinha, M, Kaur, P, Sharma, S, Singh, T.P. 登録日 2013-04-10 公開日 2013-05-01 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of the complex of type I Ribosome inactivating protein from Momordica balsamina with Methylethylamine at 1.80 A resolution To be Published
7NPJ	Crystal structure of Mycobacterium tuberculosis ArgC in complex with 6-phenoxy-3-pyridinamine 分子名称: 6-phenoxy-3-pyridinamine, N-acetyl-gamma-glutamyl-phosphate reductase 著者 Gupta, P, Mendes, V, Blundell, T.L. 登録日 2021-02-27 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (2.81 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
8QVK	Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. 分子名称: Bifunctional epoxide hydrolase 2, N-(5,5-dioxodibenzothiophen-2-yl)-4,4-difluoro-piperidine-1-carboxamide 著者 Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. 登録日 2023-10-18 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Exploring serial crystallography for drug discovery. Iucrj, 2024
8QVM	Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. 分子名称: Bifunctional epoxide hydrolase 2, TRIETHYLENE GLYCOL 著者 Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. 登録日 2023-10-18 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Exploring serial crystallography for drug discovery. Iucrj, 2024
8QWI	Comparison of room-temperature and cryogenic structures of soluble Epoxide Hydrolase with ligands bound. 分子名称: 2-(1H-BENZIMIDAZOL-2-YLSULFANYL)ETHANOL, Bifunctional epoxide hydrolase 2, SULFATE ION 著者 Dunge, A, Uwangue, O, Phan, C, Bjelcic, M, Gunnarsson, J, Wehlander, G, Kack, H, Branden, G. 登録日 2023-10-19 公開日 2024-08-14 実験手法 X-RAY DIFFRACTION (2.12 Å) 主引用文献 Exploring serial crystallography for drug discovery. Iucrj, 2024
8RKC	Capsid of bacteriophage JBD30 decorated with minor capsid protein trimers computed in I4 symmetry 分子名称: Bacteriophage Mu GpT domain-containing protein, Mu-like prophage FluMu N-terminal domain-containing protein 著者 Valentova, L, Fuzik, T, Plevka, P. 登録日 2023-12-23 公開日 2024-08-14 実験手法 ELECTRON MICROSCOPY (2.95 Å) 主引用文献 Structure and replication of Pseudomonas aeruginosa phage JBD30 Embo J., 2024
7NNI	Crystal structure of Mycobacterium tuberculosis ArgC apoenzyme 分子名称: N-acetyl-gamma-glutamyl-phosphate reductase 著者 Gupta, P, Mendes, V, Blundell, T.L. 登録日 2021-02-24 公開日 2021-06-30 最終更新日 2024-01-31 実験手法 X-RAY DIFFRACTION (1.544 Å) 主引用文献 A fragment-based approach to assess the ligandability of ArgB, ArgC, ArgD and ArgF in the L-arginine biosynthetic pathway of Mycobacterium tuberculosis Comput Struct Biotechnol J, 19, 2021
8SP5	LINE-1 retrotransposon endonuclease domain complex with Mn2+ 分子名称: LINE-1 retrotransposon endonuclease, MANGANESE (II) ION, SULFATE ION 著者 D'Ordine, A.M, Jogl, G, Sedivy, J.M. 登録日 2023-05-02 公開日 2024-05-22 実験手法 X-RAY DIFFRACTION (2.23 Å) 主引用文献 Identification and characterization of small molecule inhibitors of the LINE-1 retrotransposon endonuclease. Nat Commun, 15, 2024
6DK8	RetS kinase region without cobalt 分子名称: NICKEL (II) ION, RetS (Regulator of Exopolysaccharide and Type III Secretion) 著者 Mancl, J.M, Schubot, F.D. 登録日 2018-05-29 公開日 2019-03-20 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 Helix Cracking Regulates the Critical Interaction between RetS and GacS in Pseudomonas aeruginosa. Structure, 27, 2019
8SPW	PS3 F1 Rotorless, low ATP 分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase subunit alpha, ... 著者 Sobti, M, Stewart, A.G. 登録日 2023-05-03 公開日 2024-01-24 最終更新日 2024-04-17 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 The series of conformational states adopted by rotorless F 1 -ATPase during its hydrolysis cycle. Structure, 32, 2024
8EMC	CryoEM characterization of BrxL -- a unique AAA+ phage restriction Factor. 分子名称: Protease Lon-related BREX system protein BrxL 著者 Shen, B.W, Stoddard, B.L. 登録日 2022-09-27 公開日 2023-02-01 最終更新日 2024-06-19 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure, substrate binding and activity of a unique AAA+ protein: the BrxL phage restriction factor. Nucleic Acids Res., 51, 2023
6DLZ	Open state GluA2 in complex with STZ after micelle signal subtraction 分子名称: CYCLOTHIAZIDE, GLUTAMIC ACID, Glutamate receptor 2,Voltage-dependent calcium channel gamma-2 subunit 著者 Twomey, E.C, Yelshanskaya, M.V, Vassilevski, A.A, Sobolevsky, A.I. 登録日 2018-06-04 公開日 2018-08-22 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.9 Å) 主引用文献 Mechanisms of Channel Block in Calcium-Permeable AMPA Receptors. Neuron, 99, 2018
8F5W	Dihydropyrimidine Dehydrogenase (DPD) C671S Mutant Soaked with Dihydrothymine and NADPH Quasi-Anaerobically 分子名称: 1-DEOXY-1-(7,8-DIMETHYL-2,4-DIOXO-3,4-DIHYDRO-2H-BENZO[G]PTERIDIN-1-ID-10(5H)-YL)-5-O-PHOSPHONATO-D-RIBITOL, Dihydropyrimidine dehydrogenase [NADP(+)], FLAVIN-ADENINE DINUCLEOTIDE, ... 著者 Kaley, N, Smith, M, Forouzesh, D, Liu, D, Moran, G. 登録日 2022-11-15 公開日 2023-02-01 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (1.97 Å) 主引用文献 Mammalian dihydropyrimidine dehydrogenase: Added mechanistic details from transient-state analysis of charge transfer complexes. Arch.Biochem.Biophys., 736, 2023
8S9I	Crystal structure of the gp32 C-terminal peptide/Dda/dT8 分子名称: Dda helicase, dT8, gp32 C-terminal peptide 著者 He, X, Yun, M.K, White, S.W. 登録日 2023-03-28 公開日 2023-06-28 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (3.53 Å) 主引用文献 Crystal structure of the gp32 C-terminal peptide/Dda/dT8 To Be Published
6DMV	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Soaked for 40 s in 2 mM Mg2+ and 200 mM K+ at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-05 公開日 2018-08-15 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.52 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
8SPS	High resolution structure of ESRRB nucleosome bound OCT4 at site a and site b 分子名称: DNA (168-MER), Histone H2A type 2-C, Histone H2B type 2-E, ... 著者 Lian, T, Guan, R, Bai, Y. 登録日 2023-05-03 公開日 2023-06-28 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Structural mechanism of LIN28B nucleosome targeting by OCT4. Mol.Cell, 83, 2023
4K5U	Recognition of the BG-H Antigen by a Lamprey Variable Lymphocyte Receptor 分子名称: Variable lymphocyte receptor, beta-D-galactopyranose 著者 Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A. 登録日 2013-04-15 公開日 2013-06-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.698 Å) 主引用文献 Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor. J.Biol.Chem., 288, 2013
6DOA	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid: Reaction in 2 mM Mg2+ and 200 mM K+ for 480 s at 21 C 分子名称: 1,2-ETHANEDIOL, DNA (5'-D(*CP*GP*AP*TP*GP*T)-3'), GLYCEROL, ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-15 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.474 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018
8F7U	Macrocyclic Plasmin Inhibitor 分子名称: (5S,8R,18S,21R)-N-{[4-(aminomethyl)phenyl]methyl}-21-[(benzenesulfonyl)amino]-3,11,20-trioxo-2,5,8,12,19-pentaazatetracyclo[21.2.2.2~5,8~.2~13,16~]hentriaconta-1(25),13,15,23,26,28-hexaene-18-carboxamide, Activation peptide, GLYCEROL, ... 著者 Guojie, W. 登録日 2022-11-20 公開日 2023-02-08 実験手法 X-RAY DIFFRACTION (1.47 Å) 主引用文献 Synthesis and structural characterization of new macrocyclicplasmin inhibitors Chemmedchem, 2023
6DOI	Crystal Structure of Bacillus Halodurans Ribonuclease H1 in Complex with an RNA/DNA Hybrid (1.54 Angstrom wavelength): Soak in 0.5 mM EGTA and 200 mM K+ at 21 C 分子名称: 1,2-ETHANEDIOL, 5'-R(*AP*CP*AP*U)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), 5'-R(P*CP*G)-3' portion of intact RNA (5'-R(*AP*CP*AP*UP*CP*G)-3'), ... 著者 Samara, N.L, Yang, W. 登録日 2018-06-09 公開日 2018-08-22 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (1.948 Å) 主引用文献 Cation trafficking propels RNA hydrolysis. Nat. Struct. Mol. Biol., 25, 2018

<1410141114121413141414151416141714181419142014211422142314241425>