PDB: 215264 件ウェブページステータス検索Chemie searchBIRD

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5HBU	Structure of the E. coli nucleoid occlusion protein SlmA bound to DNA and the C-terminal tail of the cytoskeletal cell division protein FtsZ 分子名称: DNA (5'-D(*GP*TP*GP*AP*GP*TP*AP*CP*TP*CP*AP*C)-3'), FtsZ CTT peptide, Nucleoid occlusion factor SlmA 著者 Schumacher, M.A, Zeng, W. 登録日 2016-01-02 公開日 2016-04-13 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Structures of the nucleoid occlusion protein SlmA bound to DNA and the C-terminal domain of the cytoskeletal protein FtsZ. Proc.Natl.Acad.Sci.USA, 113, 2016
5HCY	EGFR kinase domain mutant "TMLR" with 3-carboxamide azaindole compound 13 分子名称: 6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]-~{N}-(oxan-4-yl)-1-propan-2-yl-pyrrolo[3,2-c]pyridine-3-carboxamide, Epidermal growth factor receptor, SULFATE ION 著者 Eigenbrot, C, Yu, C. 登録日 2016-01-04 公開日 2016-09-07 最終更新日 2024-03-06 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor. J.Med.Chem., 59, 2016
4B73	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function 分子名称: (2S)-4-amino-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 著者 Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. 登録日 2012-08-16 公開日 2012-10-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function. Nat.Chem.Biol., 8, 2012
1OJ1	Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana catesbeiana of Two Crystal Structures Complexed with (2,5 CpG) and d(ApCpGpA) 分子名称: CYTIDYL-2'-5'-PHOSPHO-GUANOSINE, RC-RNASE6 RIBONUCLEASE, SULFATE ION 著者 Tsai, C.-J, Liu, J.-H, Liao, Y.-D, Chen, L.-y, Cheng, P.-T, Sun, Y.-J. 登録日 2003-06-28 公開日 2004-07-15 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Nonproductive and Novel Binding Modes in Cytotoxic Ribonucleases from Rana Catesbeiana of Two Crystal Structures Complexed with C(2,5 Cpg) and D(Apcpgpa) To be Published
5Z3N	Structure of large fragment of DNA Polymerase I from Thermus aquaticus Host-Guest complex with the unnatural base 5fC pair with dA 分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*AP*AP*CP*GP*GP*CP*GP*CP*CP*GP*(5FC)P*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... 著者 Zeng, H, Mondal, M, Song, R.Y, Zhang, J, Xia, B, Gao, Y.Q, Yi, C.Q. 登録日 2018-01-08 公開日 2018-11-21 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Unnatural Cytosine Bases Recognized as Thymines by DNA Polymerases by the Formation of the Watson-Crick Geometry. Angew. Chem. Int. Ed. Engl., 58, 2019
1OG5	Structure of human cytochrome P450 CYP2C9 分子名称: CYTOCHROME P450 2C9, HEME C, S-WARFARIN 著者 Williams, P.A, Cosme, J, Ward, A, Angove, H.C, Matak Vinkovic, D, Jhoti, H. 登録日 2003-04-24 公開日 2003-07-17 最終更新日 2024-05-08 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal Structure of Human Cytochrome P450 2C9 with Bound Warfarin Nature, 424, 2003
2VGE	Crystal structure of the C-terminal region of human iASPP 分子名称: RELA-ASSOCIATED INHIBITOR 著者 Robinson, R.A, Lu, X, Jones, E.Y, Siebold, C. 登録日 2007-11-12 公開日 2008-02-05 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Biochemical and Structural Studies of Aspp Proteins Reveal Differential Binding to P53, P63 and P73 Structure, 16, 2008
8PNQ	Influenza A/H7N9 polymerase in elongation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]uridine, 51-mer vRNA loop (v51_mut_S), MAGNESIUM ION, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-30 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.88 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
8PNP	Influenza A/H7N9 polymerase in pre-initiation state with continuous Pol II pS5 CTD peptide mimic bound in site 1A/2A 分子名称: 51-mer vRNA loop (v51_mut_S), Polymerase acidic protein, Polymerase basic protein 2, ... 著者 Arragain, B, Cusack, S. 登録日 2023-06-30 公開日 2024-02-21 実験手法 ELECTRON MICROSCOPY (2.49 Å) 主引用文献 The host RNA polymerase II C-terminal domain is the anchor for replication of the influenza virus genome. Nat Commun, 15, 2024
5HVX	Full length Wild-Type Open-form Sodium Channel NavMs 分子名称: 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DODECAETHYLENE GLYCOL, ... 著者 Sula, A, Booker, J.E, Naylor, C.E, Wallace, B.A. 登録日 2016-01-28 公開日 2017-03-01 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (2.45 Å) 主引用文献 The complete structure of an activated open sodium channel. Nat Commun, 8, 2017
4B76	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function 分子名称: NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3, [2,4-bis(fluoranyl)-3-phenoxy-phenyl]methylazanium 著者 Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. 登録日 2012-08-16 公開日 2012-10-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.14 Å) 主引用文献 Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function. Nat.Chem.Biol., 8, 2012
5DN2	Human NRP2 b1 domain in complex with the peptide corresponding to the C-terminus of VEGF-A 分子名称: 1,4-DIETHYLENE DIOXIDE, GLYCEROL, Neuropilin-2, ... 著者 Tsai, Y.C.I, Frankel, P, Fotinou, C, Rana, R, Zachary, I, Djordjevic, S. 登録日 2015-09-09 公開日 2016-07-20 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (1.95 Å) 主引用文献 Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket. Febs J., 283, 2016
5HCX	EGFR kinase domain mutant "TMLR" with azabenzimidazole compound 7 分子名称: Epidermal growth factor receptor, SULFATE ION, ~{N}-[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]-2-methyl-1-propan-2-yl-imidazo[4,5-c]pyridin-6-amine 著者 Eigenbrot, C, Yu, C. 登録日 2016-01-04 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor. J.Med.Chem., 59, 2016
4B74	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function 分子名称: (2S)-4-[(2-ammonioethyl)amino]-N-[(1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propyl]-4-oxobutan-2-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 著者 Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. 登録日 2012-08-16 公開日 2012-10-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.18 Å) 主引用文献 Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function Nat.Chem.Biol., 8, 2012
4B2C	Structure of the factor Xa-like trypsin variant triple-Ala (TPA) in complex with eglin C 分子名称: 1,2-ETHANEDIOL, CALCIUM ION, CATIONIC TRYPSIN, ... 著者 Menzel, A, Neumann, P, Stubbs, M.T. 登録日 2012-07-13 公開日 2012-08-01 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.43 Å) 主引用文献 Thermodynamic signatures in macromolecular interactions involving conformational flexibility. Biol.Chem., 395, 2014
5B1X	Crystal structure of human dendritic cell inhibitory receptor (DCIR) C-type lectin domain in complex with biantennary glycan 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose, C-type lectin domain family 4 member A, CALCIUM ION 著者 Nagae, M, Yamaguchi, Y. 登録日 2015-12-21 公開日 2016-05-11 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.902 Å) 主引用文献 Crystal structure of human dendritic cell inhibitory receptor C-type lectin domain reveals the binding mode with N-glycan Febs Lett., 590, 2016
4ZDT	Crystal structure of the RING finger domain of Slx1 in complex with the C-terminal domain of Slx4 分子名称: GLYCEROL, SULFATE ION, Structure-specific endonuclease subunit slx1, ... 著者 Lian, F.M, Xie, S, Qian, C.M. 登録日 2015-04-19 公開日 2016-02-03 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 Crystal structure and SUMO binding of Slx1-Slx4 complex Sci Rep, 6, 2016
5HCZ	EGFR kinase domain mutant "TMLR" with 3-azetidinyl azaindazole compound 21 分子名称: 2-[1-[1-[(2~{S})-butan-2-yl]-6-[[2-(1-cyclopropylsulfonylpyrazol-4-yl)pyrimidin-4-yl]amino]pyrazolo[4,3-c]pyridin-3-yl]azetidin-3-yl]propan-2-ol, Epidermal growth factor receptor, SULFATE ION 著者 Eigenbrot, C, Yu, C. 登録日 2016-01-04 公開日 2016-09-07 最終更新日 2023-09-27 実験手法 X-RAY DIFFRACTION (2.62 Å) 主引用文献 Discovery of a Noncovalent, Mutant-Selective Epidermal Growth Factor Receptor Inhibitor. J.Med.Chem., 59, 2016
1PZU	An asymmetric NFAT1-RHR homodimer on a pseudo-palindromic, Kappa-B site 分子名称: 5'-D(*AP*AP*TP*GP*GP*AP*AP*AP*TP*TP*CP*CP*TP*C)-3', 5'-D(*TP*TP*GP*AP*GP*GP*AP*AP*TP*TP*TP*CP*CP*A)-3', Nuclear factor of activated T-cells, ... 著者 Jin, L, Sliz, P, Chen, L, Macian, F, Rao, A, Hogan, P.G, Harrison, S.C. 登録日 2003-07-14 公開日 2003-09-09 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 An asymmetric NFAT1 dimer on a pseudo-palindromic KB-like DNA site Nat.Struct.Biol., 10, 2003
3L8B	Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin 分子名称: DNA (5'-D(*AP*C*TP*(G35)P*TP*TP*AP*AP*GP*CP*AP*GP*TP*CP*CP*GP*CP*G)-3'), DNA (5'-D(*GP*CP*GP*GP*AP*CP*TP*GP*CP*TP*TP*AP*A)-3'), DNA polymerase, ... 著者 Aller, P, Ye, Y, Wallace, S.S, Burrows, C.J, Doublie, S. 登録日 2009-12-30 公開日 2010-03-09 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Crystal structure of a replicative DNA polymerase bound to the oxidized guanine lesion guanidinohydantoin. Biochemistry, 49, 2010
4B71	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function 分子名称: (1R)-1-(4-chloro-2-fluoro-3-phenoxyphenyl)propan-1-aminium, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3 著者 Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. 登録日 2012-08-16 公開日 2012-10-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function. Nat.Chem.Biol., 8, 2012
7H1W	PanDDA analysis group deposition -- Crystal Structure of ZIKV NS2B-NS3 protease in complex with Z270834034 分子名称: (2R)-2-(6,7-dihydrothieno[3,2-c]pyridin-5(4H)-yl)propan-1-amine, DIMETHYL SULFOXIDE, Serine protease NS3, ... 著者 Ni, X, Godoy, A.S, Marples, P.G, Fairhead, M, Balcomb, B.H, Tomlinson, C.W.E, Koekemoer, L, Aschenbrenner, J.C, Lithgo, R.M, Thompson, W, Wild, C, Williams, E.P, Winokan, M, Chandran, A.V, Fearon, D, Walsh, M.A, von Delft, F. 登録日 2024-04-03 公開日 2024-05-08 最終更新日 2024-05-22 実験手法 X-RAY DIFFRACTION (1.396 Å) 主引用文献 PanDDA analysis group deposition of ZIKV NS2B-NS3 protease To Be Published
4B6E	Discovery of an allosteric mechanism for the regulation of HCV NS3 protein function 分子名称: 1H-indazol-7-amine, NON-STRUCTURAL PROTEIN 4A, SERINE PROTEASE NS3, ... 著者 Saalau-Bethell, S.M, Woodhead, A.J, Chessari, G, Carr, M.G, Coyle, J, Graham, B, Hiscock, S.D, Murray, C.W, Pathuri, P, Rich, S.J, Richardson, C.J, Williams, P.A, Jhoti, H. 登録日 2012-08-09 公開日 2012-10-03 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (2.46 Å) 主引用文献 Discovery of an Allosteric Mechanism for the Regulation of Hcv Ns3 Protein Function. Nat.Chem.Biol., 8, 2012
1QBP	CRYSTAL STRUCTURE OF A BROMINATED RNA HELIX WITH FOUR MISMATCHED BASE PAIRS 分子名称: 5'-R(*UP*GP*(CBV)P*(CBV)P*AP*GP*UP*UP*CP*GP*CP*UP*GP*GP*C)-3' 著者 Anderson, A.C, O'Neil, R.H, Filman, D.J, Frederick, C.A. 登録日 1999-04-26 公開日 1999-11-26 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.1 Å) 主引用文献 Crystal structure of a brominated RNA helix with four mismatched base pairs: An investigation into RNA conformational variability. Biochemistry, 38, 1999
6J0I	Structure of [Co2+-(Chromomycin A3)2]-d(TTGGCGAA)2 complex 分子名称: 1,2-HYDRO-1-OXY-3,4-HYDRO-3-(1-METHOXY-2-OXY-3,4-DIHYDROXYPENTYL)-8,9-DIHYROXY-7-METHYLANTHRACENE, 2,6-dideoxy-4-O-methyl-alpha-D-galactopyranose-(1-3)-(2R,3R,6R)-6-hydroxy-2-methyltetrahydro-2H-pyran-3-yl acetate, 3-C-methyl-4-O-acetyl-alpha-L-Olivopyranose-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol-(1-3)-(2R,5S,6R)-6-methyltetrahydro-2H-pyran-2,5-diol, ... 著者 Satange, R.B, Chuang, C.Y, Hou, M.H. 登録日 2018-12-24 公開日 2019-07-24 最終更新日 2023-11-22 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Polymorphic G:G mismatches act as hotspots for inducing right-handed Z DNA by DNA intercalation. Nucleic Acids Res., 47, 2019

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