PDB: 222415 件ウェブページステータス検索Chemie searchBIRD

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3UV5	Crystal Structure of the tandem bromodomains of human Transcription initiation factor TFIID subunit 1 (TAF1) 分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Transcription initiation factor TFIID subunit 1 著者 Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-11-29 公開日 2012-01-18 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.03 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
3UVY	Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K16acK20ac) 分子名称: Bromodomain-containing protein 4, Histone H4 著者 Filippakopoulos, P, Felletar, I, Picaud, S, Keates, T, Muniz, J, Gileadi, O, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-11-30 公開日 2012-01-18 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
3V1U	Crystal structure of a beta-ketoacyl reductase FabG4 from Mycobacterium tuberculosis H37Rv complexed with NAD+ and Hexanoyl-CoA at 2.5 Angstrom resolution 分子名称: (2S,5R,8R,11S,14S,17S,21R)-5,8,11,14,17-PENTAMETHYL-4,7,10,13,16,19-HEXAOXADOCOSANE-2,21-DIOL, 3-oxoacyl-(Acyl-carrier-protein) reductase, HEXANOYL-COENZYME A, ... 著者 Dutta, D, Bhattacharyya, S, Das, A.K. 登録日 2011-12-10 公開日 2012-11-28 最終更新日 2023-11-08 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystal structure of hexanoyl-CoA bound to beta-ketoacyl reductase FabG4 of Mycobacterium tuberculosis Biochem.J., 450, 2013
3UWC	Structure of an aminotransferase (DegT-DnrJ-EryC1-StrS family) from Coxiella burnetii in complex with PMP 分子名称: 1,2-ETHANEDIOL, 1,4-DIETHYLENE DIOXIDE, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ... 著者 Cheung, J, Franklin, M, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J. 登録日 2011-12-01 公開日 2011-12-14 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural genomics for drug design against the pathogen Coxiella burnetii. Proteins, 83, 2015
4ONO	CD1c in complex with PM (phosphomycoketide) 分子名称: (4R,8S,16S,20R)-4,8,12,16,20-pentamethylheptacosyl dihydrogen phosphate, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin/T-cell surface glycoprotein CD1c/T-cell surface glycoprotein CD1b chimeric protein, ... 著者 Roy, S, Adams, E.J. 登録日 2014-01-28 公開日 2014-10-08 最終更新日 2020-07-29 実験手法 X-RAY DIFFRACTION (2.705 Å) 主引用文献 Molecular basis of mycobacterial lipid antigen presentation by CD1c and its recognition by alpha beta T cells. Proc.Natl.Acad.Sci.USA, 111, 2014
4NEF	X-ray structure of human Aquaporin 2 分子名称: Aquaporin-2, CADMIUM ION, ZINC ION 著者 Frick, A, Eriksson, U, Mattia, F.D, Oberg, F, Hedfalk, K, Neutze, R, Grip, W.D, Deen, P.M.T, Tornroth-horsefield, S. 登録日 2013-10-29 公開日 2014-04-16 最終更新日 2014-12-10 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 X-ray structure of human aquaporin 2 and its implications for nephrogenic diabetes insipidus and trafficking Proc.Natl.Acad.Sci.USA, 111, 2014
3V0M	Crystal structure of the Fucosylgalactoside alpha N-acetylgalactosaminyltransferase (GTA, cisAB mutant L266G, G268A) in complex with a novel UDP-Gal derived inhibitor (5GW) and H-antigen acceptor 分子名称: 5-phenyluridine 5'-(trihydrogen diphosphate), Histo-blood group ABO system transferase, MANGANESE (II) ION, ... 著者 Palcic, M.M, Jorgensen, R. 登録日 2011-12-08 公開日 2013-01-23 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (1.68 Å) 主引用文献 Base-modified Donor Analogues Reveal Novel Dynamic Features of a Glycosyltransferase. J.Biol.Chem., 288, 2013
4O6S	1.32A resolution structure of the hemophore HasA from Pseudomonas aeruginosa (H83A mutant, Zinc Bound) 分子名称: 1,2-ETHANEDIOL, HasAp, PROTOPORPHYRIN IX CONTAINING FE, ... 著者 Lovell, S, Kumar, R, Battaile, K.P, Matsumura, H, Yao, H, Rodriguez, J.C, Moenne-Loccoz, P, Rivera, M. 登録日 2013-12-23 公開日 2014-03-26 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.32 Å) 主引用文献 Replacing the Axial Ligand Tyrosine 75 or Its Hydrogen Bond Partner Histidine 83 Minimally Affects Hemin Acquisition by the Hemophore HasAp from Pseudomonas aeruginosa. Biochemistry, 53, 2014
4OPS	Crystal structure of P domain from norovirus strain Farmington Hills 2004 in complex with HBGA type Leb (tetraglycan) 分子名称: Major capsid protein, alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-3)-[alpha-L-fucopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose 著者 Singh, B.K, Leuthold, M, Hansman, G.S. 登録日 2014-02-06 公開日 2014-12-17 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.76 Å) 主引用文献 Human noroviruses' fondness for histo-blood group antigens. J.Virol., 89, 2015
3RH7	Crystal structure of a putative oxidoreductase (SMa0793) from Sinorhizobium meliloti 1021 at 3.00 A resolution 分子名称: FLAVIN MONONUCLEOTIDE, Hypothetical oxidoreductase 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-04-11 公開日 2011-06-08 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (3 Å) 主引用文献 Crystal structure of a Hypothetical oxidoreductase (SMa0793) from SINORHIZOBIUM MELILOTI 1021 at 3.00 A resolution To be published
4NI2	Crystal structure of the heterodimeric catalytic domain of wild-type human soluble guanylate cyclase 分子名称: 1,2-ETHANEDIOL, Guanylate cyclase soluble subunit alpha-3, Guanylate cyclase soluble subunit beta-1 著者 Seeger, F, Williams, G.J, Tainer, J.A, Garcin, E.D. 登録日 2013-11-05 公開日 2014-04-16 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Interfacial residues promote an optimal alignment of the catalytic center in human soluble guanylate cyclase: heterodimerization is required but not sufficient for activity. Biochemistry, 53, 2014
3UNM	Crystal Structure of The Human MDC1 FHA Domain 分子名称: Mediator of DNA damage checkpoint protein 1 著者 Luo, S, Ye, K. 登録日 2011-11-16 公開日 2012-01-25 最終更新日 2023-11-01 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain Nucleic Acids Res., 40, 2012
3UPL	Crystal structure of the Brucella abortus enzyme catalyzing the first committed step of the methylerythritol 4-phosphate pathway. 分子名称: GLYCEROL, MAGNESIUM ION, Oxidoreductase 著者 Calisto, B.M, Perez-Gil, J, Fita, I, Rodriguez-Concepcion, M. 登録日 2011-11-18 公開日 2012-03-28 最終更新日 2024-03-13 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Crystal structure of Brucella abortus deoxyxylulose-5-phosphate reductoisomerase-like (DRL) enzyme involved in isoprenoid biosynthesis. J.Biol.Chem., 287, 2012
3UQR	Crystal structure of BACE1 with its inhibitor 分子名称: Beta-secretase 1, METHYL (2S)-1-[(2R,5S,8S,12S,13S)-2,13-DIBENZYL-12-HYDROXY-3,5-DIMETHYL-15-(3-[METHYL(METHYLSULFONYL)AMINO]-5-{[(1R)-1-PHENYLETHYL]CARBAMOYL}PHENYL)-8-(2-METHYLPROPYL)-4,7,10,15-TETRAOXO-3,6,9,14-TETRAAZAPENTADECAN-1-OYL]PYRROLIDINE-2-CARBOXYLATE 著者 Chen, T.T, Chen, W.Y, Li, L, Xu, Y.C. 登録日 2011-11-21 公開日 2012-11-21 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (3.056 Å) 主引用文献 Cyanobacterial Peptides as a Prototype for the Design of Potent beta-Secretase Inhibitors and the Development of Selective Chemical Probes for Other Aspartic Proteases J.Med.Chem., 55, 2012
4OKI	X-ray structure of the nucleotide-binding subdomain of the enoylreductase domain of PpsC from Mycobacterium tuberculosis 分子名称: (4S)-2-METHYL-2,4-PENTANEDIOL, Phthiocerol synthesis polyketide synthase type I PpsC, SODIUM ION 著者 Faille, A, Mourey, L, Pedelacq, J.D. 登録日 2014-01-22 公開日 2015-08-05 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.5 Å) 主引用文献 Insights into the catalytic mechanism of the DH domain of the Mycobacterium tuberculosis polyketide synthase PpsC and architecture of the beta-carbon processing domains To be Published
3US5	Crystal structure of a RNA-binding domain of a poly-U binding splicing factor 60KDa (PUF60) from Homo sapiens at 1.38 A resolution 分子名称: CHLORIDE ION, Poly(U)-binding-splicing factor PUF60 著者 Joint Center for Structural Genomics (JCSG), Partnership for T-Cell Biology (TCELL) 登録日 2011-11-23 公開日 2012-01-11 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.38 Å) 主引用文献 Crystal structure of a RNA-binding domain of a poly-U binding splicing factor 60KDa (PUF60) from Homo sapiens at 1.38 A resolution To be published
4OLN	Ancestral Steroid Receptor 1 in complex with estrogen response element DNA 分子名称: 5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*GP*AP*GP*TP*GP*AP*CP*CP*TP*GP*A)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*CP*TP*GP*AP*CP*CP*TP*GP*G)-3', AncSR1, ... 著者 Ortlund, E.O, Murphy, M.N. 登録日 2014-01-24 公開日 2014-10-29 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell(Cambridge,Mass.), 159, 2014
3UT1	Crystal structure of the 3-MBT repeat domain of L3MBTL3 分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COBALT (II) ION, Lethal(3)malignant brain tumor-like protein 3, ... 著者 Zhong, N, Tempel, W, Wernimont, A.K, Graslund, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2011-11-24 公開日 2011-12-28 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.05 Å) 主引用文献 Crystal structure of the 3-MBT repeat domain of L3MBTL3 to be published
4O6C	West Nile Virus Non-structural protein 1 (NS1) Form 2 crystal 分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, NS1, SULFATE ION 著者 Akey, D.L, Smith, J.L. 登録日 2013-12-20 公開日 2014-02-19 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (2.7508 Å) 主引用文献 Flavivirus NS1 structures reveal surfaces for associations with membranes and the immune system. Science, 343, 2014
4O8X	Zinc-bound Rpn11 in complex with Rpn8 分子名称: 1,2-ETHANEDIOL, 26S proteasome regulatory subunit RPN11, 26S proteasome regulatory subunit RPN8, ... 著者 Worden, E.J, Padovani, C, Martin, A. 登録日 2013-12-30 公開日 2014-01-22 最終更新日 2023-09-20 実験手法 X-RAY DIFFRACTION (1.991 Å) 主引用文献 Structure of the Rpn11-Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation. Nat.Struct.Mol.Biol., 21, 2014
4ONK	[Leu-5]-Enkephalin mutant - YVVFL 分子名称: [Leu-5]-Enkephalin mutant - YVVFL 著者 Sangwan, S, Eisenberg, D, Sawaya, M.R, Do, T.D, Bowers, M.T, Lapointe, N.E, Teplow, D.B, Feinstein, S.C. 登録日 2014-01-28 公開日 2014-07-02 最終更新日 2024-04-03 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Factors that drive Peptide assembly from native to amyloid structures: experimental and theoretical analysis of [leu-5]-enkephalin mutants. J.Phys.Chem.B, 118, 2014
3R12	Crystal structure of a Deoxyribose-phosphate aldolase (TM_1559) from THERMOTOGA MARITIMA at 1.75 A resolution 分子名称: CITRIC ACID, Deoxyribose-phosphate aldolase, GLYCEROL, ... 著者 Joint Center for Structural Genomics (JCSG) 登録日 2011-03-09 公開日 2011-04-20 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (1.75 Å) 主引用文献 Crystal structure of a Deoxyribose-phosphate aldolase (TM_1559) from THERMOTOGA MARITIMA at 1.75 A resolution To be published
4OAI	Crystal structure of the cytosolic domain of mouse MiD51 dimer mutant 分子名称: Mitochondrial dynamic protein MID51, SULFATE ION 著者 Loson, O.C, Kaiser, J.T, Chan, D.C. 登録日 2014-01-04 公開日 2014-01-22 最終更新日 2024-02-28 実験手法 X-RAY DIFFRACTION (2 Å) 主引用文献 The Mitochondrial Fission Receptor MiD51 Requires ADP as a Cofactor. Structure, 22, 2014
3UVX	Crystal Structure of the first bromodomain of human BRD4 in complex with a diacetylated histone 4 peptide (H4K12acK16ac) 分子名称: 1,2-ETHANEDIOL, Bromodomain-containing protein 4, FORMIC ACID, ... 著者 Filippakopoulos, P, Picaud, S, Keates, T, Ugochukwu, E, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Weigelt, J, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) 登録日 2011-11-30 公開日 2012-01-25 最終更新日 2023-12-06 実験手法 X-RAY DIFFRACTION (1.91 Å) 主引用文献 Histone recognition and large-scale structural analysis of the human bromodomain family. Cell(Cambridge,Mass.), 149, 2012
3UWN	The 3-MBT repeat domain of L3MBTL1 in complex with a methyl-lysine mimic 分子名称: Lethal(3)malignant brain tumor-like protein 1, UNKNOWN ATOM OR ION, [2-(phenylamino)benzene-1,4-diyl]bis{[4-(pyrrolidin-1-yl)piperidin-1-yl]methanone} 著者 Zhong, N, Tempel, W, Wernimont, A.K, Graslund, S, Ingerman, L.A, Korboukh, V, Kireev, D.B, Gao, C, Frye, S.V, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Brown, P.J, Structural Genomics Consortium (SGC) 登録日 2011-12-02 公開日 2012-03-07 最終更新日 2023-09-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 The 3-MBT repeat domain of L3MBTL1 in complex with a methyl-lysine mimic To be Published

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