4NEF
X-ray structure of human Aquaporin 2
Summary for 4NEF
Entry DOI | 10.2210/pdb4nef/pdb |
Descriptor | Aquaporin-2, CADMIUM ION, ZINC ION, ... (4 entities in total) |
Functional Keywords | water channel, cadmium binding, membrane protein |
Biological source | Homo sapiens (human) |
Cellular location | Apical cell membrane ; Multi-pass membrane protein : P41181 |
Total number of polymer chains | 4 |
Total formula weight | 101235.57 |
Authors | Frick, A.,Eriksson, U.,Mattia, F.D.,Oberg, F.,Hedfalk, K.,Neutze, R.,Grip, W.D.,Deen, P.M.T.,Tornroth-horsefield, S. (deposition date: 2013-10-29, release date: 2014-04-16, Last modification date: 2014-12-10) |
Primary citation | Frick, A.,Eriksson, U.K.,de Mattia, F.,Oberg, F.,Hedfalk, K.,Neutze, R.,de Grip, W.J.,Deen, P.M.,Tornroth-Horsefield, S. X-ray structure of human aquaporin 2 and its implications for nephrogenic diabetes insipidus and trafficking Proc.Natl.Acad.Sci.USA, 111:6305-6310, 2014 Cited by PubMed: 24733887DOI: 10.1073/pnas.1321406111 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.75 Å) |
Structure validation
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