4NEF
X-ray structure of human Aquaporin 2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Aquaporin-2 | polymer | 242 | 25236.3 | 4 | UniProt (P41181) Pfam (PF00230) | Homo sapiens (human) | AQP-2, ADH water channel, Aquaporin-CD, AQP-CD, Collecting duct water channel protein, WCH-CD, Water channel protein for renal collecting duct |
| 2 | E, G (A, D) | CADMIUM ION | non-polymer | 112.4 | 2 | Chemie (CD) | |||
| 3 | F (A) | ZINC ION | non-polymer | 65.4 | 1 | Chemie (ZN) | |||
| 4 | H, I, J, K (A, B, C, D) | water | water | 18.0 | 59 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 3 - 241 (UniProt: P41181)
| PDB | External Database | Details |
|---|---|---|
| Gly 1 | - | expression tag |
| Ser 2 | - | expression tag |
| Pro 242 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 100945.3 | |
| Non-Polymers* | Number of molecules | 3 |
| Total formula weight | 290.2 | |
| All* | Total formula weight | 101235.6 |
