6FBE
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![BU of 6fbe by Molmil](/molmil-images/mine/6fbe) | KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the third primer nucleotide. | 分子名称: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*GP*GP*TP*GP*CP*GP*TP*GP*GP*TP*C)-3'), ... | 著者 | Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2017-12-19 | 公開日 | 2018-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.589 Å) | 主引用文献 | Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4BDP
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![BU of 4bdp by Molmil](/molmil-images/mine/4bdp) | CRYSTAL STRUCTURE OF BACILLUS DNA POLYMERASE I FRAGMENT COMPLEXED TO 11 BASE PAIRS OF DUPLEX DNA AFTER ADDITION OF TWO DATP RESIDUES | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*AP*TP*GP*CP*AP*A)-3'), DNA (5'-D(*TP*AP*TP*TP*GP*CP*AP*TP*GP*AP*TP*GP*C)-3'), MAGNESIUM ION, ... | 著者 | Kiefer, J.R, Mao, C, Beese, L.S. | 登録日 | 1997-11-17 | 公開日 | 1999-01-13 | 最終更新日 | 2023-08-02 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Visualizing DNA replication in a catalytically active Bacillus DNA polymerase crystal. Nature, 391, 1998
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8TL1
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8TL8
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![BU of 8tl8 by Molmil](/molmil-images/mine/8tl8) | Structure of Orthoreovirus RNA Chaperone SigmaNS R6A mutant in complex with bile acid | 分子名称: | GLYCOCHOLIC ACID, Protein sigma-NS | 著者 | Prasad, B.V.V, Zhao, B, Hu, L, Neetu, N. | 登録日 | 2023-07-26 | 公開日 | 2024-03-06 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of orthoreovirus RNA chaperone sigma NS, a component of viral replication factories. Nat Commun, 15, 2024
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6FBF
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![BU of 6fbf by Molmil](/molmil-images/mine/6fbf) | KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the fourth primer nucleotide. | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*CP*GP*GP*TP*GP*CP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*GP*CP*AP*(OH3)P*CP*GP*C)-3'), ... | 著者 | Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2017-12-19 | 公開日 | 2018-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.001 Å) | 主引用文献 | Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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8TKA
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6FBC
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![BU of 6fbc by Molmil](/molmil-images/mine/6fbc) | KlenTaq DNA polymerase processing a modified primer - bearing the modification at the 3'-terminus of the primer. | 分子名称: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... | 著者 | Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2017-12-19 | 公開日 | 2018-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.54 Å) | 主引用文献 | Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6FBD
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![BU of 6fbd by Molmil](/molmil-images/mine/6fbd) | KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the second primer nucleotide. | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*AP*(OH3)P*C)-3'), DNA (5'-D(P*AP*AP*AP*CP*GP*GP*TP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... | 著者 | Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2017-12-19 | 公開日 | 2018-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.099 Å) | 主引用文献 | Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6FBG
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![BU of 6fbg by Molmil](/molmil-images/mine/6fbg) | KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the fifth primer nucleotide. | 分子名称: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*CP*CP*GP*GP*TP*GP*TP*GP*GP*TP*C)-3'), ... | 著者 | Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2017-12-19 | 公開日 | 2018-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.702 Å) | 主引用文献 | Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6FBH
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![BU of 6fbh by Molmil](/molmil-images/mine/6fbh) | KlenTaq DNA polymerase processing a modified primer - bearing the modification upstream at the sixth primer nucleotide. | 分子名称: | 1,2-ETHANEDIOL, 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*AP*AP*CP*GP*TP*CP*CP*GP*GP*TP*GP*GP*GP*TP*C)-3'), ... | 著者 | Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2017-12-19 | 公開日 | 2018-09-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Snapshots of a modified nucleotide moving through the confines of a DNA polymerase. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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1EXD
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![BU of 1exd by Molmil](/molmil-images/mine/1exd) | CRYSTAL STRUCTURE OF A TIGHT-BINDING GLUTAMINE TRNA BOUND TO GLUTAMINE AMINOACYL TRNA SYNTHETASE | 分子名称: | ADENOSINE MONOPHOSPHATE, GLUTAMINE TRNA APTAMER, GLUTAMINYL-TRNA SYNTHETASE, ... | 著者 | Bullock, T.L, Sherlin, L.D, Perona, J.J. | 登録日 | 2000-05-02 | 公開日 | 2000-05-15 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Tertiary core rearrangements in a tight binding transfer RNA aptamer. Nat.Struct.Biol., 7, 2000
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3UDL
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![BU of 3udl by Molmil](/molmil-images/mine/3udl) | 3-heterocyclyl quinolone bound to HCV NS5B | 分子名称: | 3-(5-benzyl-1,2,4-oxadiazol-3-yl)-6-fluoro-1-[2-fluoro-4-(trifluoromethyl)benzyl]-7-(4-methylpiperazin-1-yl)quinolin-4(1H)-one, HCV NS5B polymerase | 著者 | Somoza, J.R. | 登録日 | 2011-10-28 | 公開日 | 2011-12-21 | 実験手法 | X-RAY DIFFRACTION (2.174 Å) | 主引用文献 | Quinolones as HCV NS5B polymerase inhibitors. Bioorg.Med.Chem.Lett., 21, 2011
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5W35
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![BU of 5w35 by Molmil](/molmil-images/mine/5w35) | |
7QH5
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![BU of 7qh5 by Molmil](/molmil-images/mine/7qh5) | |
5W33
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![BU of 5w33 by Molmil](/molmil-images/mine/5w33) | |
5W36
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5E41
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![BU of 5e41 by Molmil](/molmil-images/mine/5e41) | Crystal structure of the large fragment of DNA Polymerase I from Thermus aquaticus in a closed ternary complex with 5-(N-(10-hydroxydecanoyl)-aminopentenyl)-2'-deoxyuridine-triphosphate | 分子名称: | 2'-deoxy-5-{(1E)-5-[(10-hydroxydecanoyl)amino]pent-1-en-1-yl}uridine 5'-(tetrahydrogen triphosphate), DNA (5'-D(*AP*AP*AP*AP*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), ... | 著者 | Hottin, A, Betz, K, Marx, A. | 登録日 | 2015-10-05 | 公開日 | 2016-12-07 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural Basis for the KlenTaq DNA Polymerase Catalysed Incorporation of Alkene- versus Alkyne-Modified Nucleotides. Chemistry, 23, 2017
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5W34
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3DOG
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![BU of 3dog by Molmil](/molmil-images/mine/3dog) | Structure of Thr 160 phosphorylated CDK2/cyclin A in complex with the inhibitor N-&-N1 | 分子名称: | (2R)-2-{[4-(benzylamino)-8-(1-methylethyl)pyrazolo[1,5-a][1,3,5]triazin-2-yl]amino}butan-1-ol, Cell division protein kinase 2, Cyclin-A2, ... | 著者 | Echalier, A, Endicott, J. | 登録日 | 2008-07-04 | 公開日 | 2008-09-30 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | N-&-N, a new class of cell death-inducing kinase inhibitors derived from the purine roscovitine. Mol.Cancer Ther., 7, 2008
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1RZT
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![BU of 1rzt by Molmil](/molmil-images/mine/1rzt) | Crystal structure of DNA polymerase lambda complexed with a two nucleotide gap DNA molecule | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*CP*GP*GP*CP*AP*AP*CP*GP*CP*AP*C)-3', 5'-D(*GP*TP*GP*CP*G)-3', ... | 著者 | Pedersen, L.C, Garcia-Diaz, M, Bebenek, K, Krahn, J.M, Blanco, L, Kunkel, T.A. | 登録日 | 2003-12-29 | 公開日 | 2004-03-02 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | A structural solution for the DNA polymerase lambda-dependent repair of DNA gaps with minimal homology. Mol.Cell, 13, 2004
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4DQS
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![BU of 4dqs by Molmil](/molmil-images/mine/4dqs) | Binary complex of Bacillus DNA Polymerase I Large Fragment and duplex DNA with rC in primer terminus paired with dG of template | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*GP*A*CP*GP*TP*AP*CP*GP*TP*GP*AP*TP*CP*GP*CP*A)-3'), DNA polymerase, ... | 著者 | Wang, W, Beese, L.S. | 登録日 | 2012-02-16 | 公開日 | 2012-06-06 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.66 Å) | 主引用文献 | Structural factors that determine selectivity of a high fidelity DNA polymerase for deoxy-, dideoxy-, and ribonucleotides. J.Biol.Chem., 287, 2012
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1EUQ
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![BU of 1euq by Molmil](/molmil-images/mine/1euq) | CRYSTAL STRUCTURE OF GLUTAMINYL-TRNA SYNTHETASE COMPLEXED WITH A TRNA-GLN MUTANT AND AN ACTIVE-SITE INHIBITOR | 分子名称: | 5'-O-[N-(L-GLUTAMINYL)-SULFAMOYL]ADENOSINE, GLUTAMINYL TRNA, GLUTAMINYL-TRNA SYNTHETASE | 著者 | Sherlin, L.D, Bullock, T.L, Newberry, K.J, Lipman, R.S.A, Hou, Y.-M, Beijer, B, Sproat, B.S, Perona, J.J. | 登録日 | 2000-04-17 | 公開日 | 2000-06-04 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Influence of transfer RNA tertiary structure on aminoacylation efficiency by glutaminyl and cysteinyl-tRNA synthetases. J.Mol.Biol., 299, 2000
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2VOD
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![BU of 2vod by Molmil](/molmil-images/mine/2vod) | Crystal structure of N-terminal domains of Human La protein complexed with RNA oligomer AUAUUUU | 分子名称: | 5'-R(*AP*UP*AP*UP*UP*UP*UP)-3', LUPUS LA PROTEIN | 著者 | Kotik-Kogan, O, Valentine, E.R, Sanfelice, D, Conte, M.R, Curry, S. | 登録日 | 2008-02-15 | 公開日 | 2008-05-06 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structural Analysis Reveals Conformational Plasticity in the Recognition of RNA 3' Ends by the Human La Protein. Structure, 16, 2008
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7KQM
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![BU of 7kqm by Molmil](/molmil-images/mine/7kqm) | Binary complex of TERT (telomerase reverse transcriptase) with RNA/telomeric DNA hybrid | 分子名称: | 1,2-ETHANEDIOL, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*TP*TP*CP*TP*TP*TP*GP*TP*GP*CP*AP*CP*CP*TP*G)-3'), ... | 著者 | Choi, W.S, Weng, P.J, Yang, W. | 登録日 | 2020-11-17 | 公開日 | 2022-03-23 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.73 Å) | 主引用文献 | Flexibility of telomerase in binding the RNA template and DNA telomeric repeat. Proc.Natl.Acad.Sci.USA, 119, 2022
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6Q4T
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![BU of 6q4t by Molmil](/molmil-images/mine/6q4t) | KOD DNA pol in a closed ternary complex with 7-deaza-7-(2-(2-hydroxyethoxy)-N-(prop-2-yn-1-yl)acetamide)-2-dATP | 分子名称: | 1,2-ETHANEDIOL, DNA (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*CP*AP*C)-3'), DNA (5'-D(P*AP*AP*CP*TP*GP*TP*GP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), ... | 著者 | Kropp, H.M, Diederichs, K, Marx, A. | 登録日 | 2018-12-06 | 公開日 | 2019-02-27 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.997 Å) | 主引用文献 | The Structure of an Archaeal B-Family DNA Polymerase in Complex with a Chemically Modified Nucleotide. Angew.Chem.Int.Ed.Engl., 58, 2019
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