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8P82
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BU of 8p82 by Molmil
Cryo-EM structure of dimeric UBR5
分子名称: E3 ubiquitin-protein ligase UBR5, ZINC ION
著者Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H.
登録日2023-05-31
公開日2023-06-14
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (3.36 Å)
主引用文献UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol.Cell, 83, 2023
8P83
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BU of 8p83 by Molmil
Cryo-EM structure of full-length human UBR5 (homotetramer)
分子名称: E3 ubiquitin-protein ligase UBR5
著者Aguirre, J.D, Kater, L, Kempf, G, Cavadini, S, Thoma, N.H.
登録日2023-05-31
公開日2023-06-14
最終更新日2023-08-16
実験手法ELECTRON MICROSCOPY (3.87 Å)
主引用文献UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.
Mol.Cell, 83, 2023
6IMQ
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BU of 6imq by Molmil
Crystal structure of PML B1-box multimers
分子名称: CHLORIDE ION, Protein PML, ZINC ION
著者Li, Y, Ma, X, Chen, Z, Wu, H, Wang, P, Wu, W, Cheng, N, Zeng, L, Zhang, H, Cai, X, Chen, S.J, Chen, Z, Meng, G.
登録日2018-10-23
公開日2019-07-31
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.06 Å)
主引用文献B1 oligomerization regulates PML nuclear body biogenesis and leukemogenesis.
Nat Commun, 10, 2019
8DJH
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BU of 8djh by Molmil
Ternary complex of SUMO1 with a phosphomimetic SIM of PML and zinc
分子名称: PML 4SD, Small ubiquitin-related modifier 1, ZINC ION
著者Lussier-Price, M, Wahba, H.M, Mascle, X.H, Cappadocia, L, Bourdeau, V, Gagnon, C, Igelmann, S, Sakaguchi, K, Ferbeyre, G, Omichinski, J.G.
登録日2022-06-30
公開日2022-08-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1.
Nucleic Acids Res., 50, 2022
8DJI
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BU of 8dji by Molmil
Ternary complex of SUMO1 with the SIM of PML and zinc
分子名称: Protein PML, Small ubiquitin-related modifier 1, ZINC ION
著者Lussier-Price, M, Wahba, H.M, Mascle, X.H, Cappadocia, L, Bourdeau, V, Gagnon, C, Igelmann, S, Sakaguchi, K, Ferbeyre, G, Omichinski, J.G.
登録日2022-06-30
公開日2022-08-10
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Zinc controls PML nuclear body formation through regulation of a paralog specific auto-inhibition in SUMO1.
Nucleic Acids Res., 50, 2022
4WJN
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BU of 4wjn by Molmil
Crystal structure of SUMO1 in complex with phosphorylated PML
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G.
登録日2014-10-01
公開日2014-12-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1.
Structure, 23, 2015
4WJO
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BU of 4wjo by Molmil
Crystal Structure of SUMO1 in complex with PML
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Cappadocia, L, Mascle, X.H, Bourdeau, V, Tremblay-Belzile, S, Chaker-Margot, M, Lussier-Price, M, Wada, J, Sakaguchi, K, Aubry, M, Ferbeyre, G, Omichinski, J.G.
登録日2014-10-01
公開日2014-12-31
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.46 Å)
主引用文献Structural and Functional Characterization of the Phosphorylation-Dependent Interaction between PML and SUMO1.
Structure, 23, 2015
6UYU
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Crystal structure of K45-acetylated SUMO1 in complex with phosphorylated PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6UYO
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BU of 6uyo by Molmil
Crystal structure of K37-acetylated SUMO1 in complex with PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.639 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6UYQ
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BU of 6uyq by Molmil
Crystal structure of K45-acetylated SUMO1 in complex with PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.501 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6UYR
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BU of 6uyr by Molmil
Crystal structure of K46-acetylated SUMO1 in complex with PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.3 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6UYP
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BU of 6uyp by Molmil
Crystal structure of K39-acetylated SUMO1 in complex with PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.418 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6UYT
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BU of 6uyt by Molmil
Crystal structure of K39-acetylated SUMO1 in complex with phosphorylated PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.662 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6UYV
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BU of 6uyv by Molmil
Crystal structure of K46-acetylated SUMO1 in complex with phosphorylated PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.401 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
6UYS
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BU of 6uys by Molmil
Crystal structure of K37-acetylated SUMO1 in complex with phosphorylated PML-SIM
分子名称: Protein PML, Small ubiquitin-related modifier 1
著者Wahba, H.M, Gagnon, C, Mascle, X.H, Lussier-Price, M, Cappadocia, L, Sakaguchi, K, Omichinski, J.G.
登録日2019-11-14
公開日2019-11-27
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Acetylation of SUMO1 Alters Interactions with the SIMs of PML and Daxx in a Protein-Specific Manner.
Structure, 28, 2020
1QCY
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BU of 1qcy by Molmil
THE CRYSTAL STRUCTURE OF THE I-DOMAIN OF HUMAN INTEGRIN ALPHA1BETA1
分子名称: I-DOMAIN OF INTEGRIN ALPHA1BETA1, MAGNESIUM ION
著者Kankare, J.A, Salminen, T.A, Nymalm, Y, Kaepylae, J, Heino, J, Johnson, M.S.
登録日1999-05-12
公開日2003-09-02
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Jararhagin-derived RKKH Peptides Induce Structural Changes in a1I Domain of Human Integrin a1b1
J.Biol.Chem., 279, 2004
2PP3
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BU of 2pp3 by Molmil
Crystal structure of L-talarate/galactarate dehydratase mutant K197A liganded with Mg and L-glucarate
分子名称: L-GLUCARIC ACID, L-talarate/galactarate dehydratase, MAGNESIUM ION
著者Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C.
登録日2007-04-27
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
Biochemistry, 46, 2007
2PP1
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BU of 2pp1 by Molmil
Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2 liganded with Mg and L-lyxarohydroxamate
分子名称: (2R,3S,4R)-2,3,4-TRIHYDROXY-5-(HYDROXYAMINO)-5-OXOPENTANOIC ACID, L-talarate/galactarate dehydratase, MAGNESIUM ION
著者Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C.
登録日2007-04-27
公開日2007-08-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
Biochemistry, 46, 2007
2PP0
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BU of 2pp0 by Molmil
Crystal structure of L-talarate/galactarate dehydratase from Salmonella typhimurium LT2
分子名称: GLYCEROL, L-talarate/Galactarate Dehydratase
著者Fedorov, A.A, Fedorov, E.V, Yew, W.S, Gerlt, J.A, Almo, S.C.
登録日2007-04-27
公開日2007-08-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Evolution of enzymatic activities in the enolase superfamily: L-talarate/galactarate dehydratase from Salmonella typhimurium LT2.
Biochemistry, 46, 2007
1PT6
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BU of 1pt6 by Molmil
I domain from human integrin alpha1-beta1
分子名称: GLYCEROL, Integrin alpha-1, MAGNESIUM ION
著者Nymalm, Y, Puranen, J.S, Nyholm, T.K.M, Kapyla, J, Kidron, H, Pentikainen, O, Airenne, T.T, Heino, J, Slotte, J.P, Johnson, M.S, Salminen, T.A.
登録日2003-06-23
公開日2004-04-13
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.87 Å)
主引用文献Jararhagin-derived RKKH peptides induce structural changes in alpha1I domain of human integrin alpha1beta1.
J.Biol.Chem., 279, 2004
3CB3
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BU of 3cb3 by Molmil
Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate
分子名称: L-GLUCARIC ACID, MAGNESIUM ION, Mandelate racemase/muconate lactonizing enzyme
著者Fedorov, A.A, Fedorov, E.V, Yew, W.S, Burley, S.K, Gerlt, J.A, Almo, S.C, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2008-02-21
公開日2008-03-04
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of L-Talarate dehydratase from Polaromonas sp. JS666 complexed with Mg and L-glucarate.
To be Published
5JYQ
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BU of 5jyq by Molmil
Structure of Conus Geographus insulin G1
分子名称: Insulin 1, Insulin 1b, SULFATE ION
著者Lawrence, M.C, Menting, J, Norton, R.S, Safavi-Hemami, H.
登録日2016-05-15
公開日2016-09-07
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献A minimized human insulin-receptor-binding motif revealed in a Conus geographus venom insulin.
Nat.Struct.Mol.Biol., 23, 2016
3WNV
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BU of 3wnv by Molmil
Crystal structure of a glyoxylate reductase from Paecilomyes thermophila
分子名称: SULFATE ION, glyoxylate reductase
著者Duan, X, Hu, S, Zhou, P, Zhou, Y, Jiang, Z.
登録日2013-12-17
公開日2014-12-03
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Characterization and crystal structure of a first fungal glyoxylate reductase from Paecilomyes thermophila
Enzyme.Microb.Technol., 60, 2014
1SBX
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BU of 1sbx by Molmil
Crystal structure of the Dachshund-homology domain of human SKI
分子名称: Ski oncogene
著者Wilson, J.J, Malakhova, M, Zhang, R, Joachimiak, A, Hegde, R.S.
登録日2004-02-11
公開日2004-05-25
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal Structure of the Dachshund Homology Domain of human SKI
Structure, 12, 2004
2OG9
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BU of 2og9 by Molmil
Crystal Structure of mandelate racemase/muconate lactonizing enzyme from Polaromonas sp. JS666
分子名称: CALCIUM ION, Mandelate racemase/muconate lactonizing enzyme
著者Kumaran, D, Burley, S.K, Swaminathan, S, New York SGX Research Center for Structural Genomics (NYSGXRC)
登録日2007-01-05
公開日2007-02-27
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal Structure of mandelate racemase/muconate lactonizing enzyme from Polaromonas sp. JS666
To be Published

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件を2024-08-07に公開中

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