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4V9M
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70S Ribosome translocation intermediate FA-4.2A containing elongation factor EFG/FUSIDIC ACID/GDP, mRNA, and tRNA bound in the pe*/E state.
分子名称: 23S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ...
著者Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
登録日2013-04-25
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Crystal structures of EF-G-ribosome complexes trapped in intermediate states of translocation.
Science, 340, 2013
4V9N
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BU of 4v9n by Molmil
Crystal structure of the 70S ribosome bound with the Q253P mutant of release factor RF2.
分子名称: 16S rRNA (1504-MER), 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Santos, N, Zhu, J, Donohue, J.P, Korostelev, A.A, Noller, H.F.
登録日2013-04-26
公開日2014-07-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structure of the 70S Ribosome Bound with the Q253P Mutant Form of Release Factor RF2.
Structure, 21, 2013
4V9O
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Control of ribosomal subunit rotation by elongation factor G
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Pulk, A, Cate, J.H.D.
登録日2013-05-03
公開日2014-07-09
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Control of ribosomal subunit rotation by elongation factor G.
Science, 340, 2013
4V9P
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Control of ribosomal subunit rotation by elongation factor G
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Pulk, A, Cate, J.H.D.
登録日2013-05-03
公開日2014-07-09
最終更新日2014-12-17
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Control of ribosomal subunit rotation by elongation factor G.
Science, 340, 2013
4V9Q
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BU of 4v9q by Molmil
Crystal Structure of Blasticidin S Bound to Thermus Thermophilus 70S Ribosome.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Svidritskiy, E, Ling, C, Ermolenko, D.N, Korostelev, A.A.
登録日2013-06-12
公開日2014-07-09
最終更新日2019-07-17
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Blasticidin S inhibits translation by trapping deformed tRNA on the ribosome.
Proc.Natl.Acad.Sci.USA, 110, 2013
4V9R
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BU of 4v9r by Molmil
Crystal structure of antibiotic DITYROMYCIN bound to 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
登録日2013-12-05
公開日2014-07-09
最終更新日2014-12-10
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
4V9S
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BU of 4v9s by Molmil
Crystal structure of antibiotic GE82832 bound to 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Bulkley, D.P, Brandi, L, Polikanov, Y.S, Fabbretti, A, O'Connor, M, Gualerzi, C.O, Steitz, T.A.
登録日2013-12-05
公開日2014-07-09
最終更新日2018-06-27
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献The antibiotics dityromycin and GE82832 bind protein S12 and block EF-G-catalyzed translocation.
Cell Rep, 6, 2014
4W29
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70S ribosome translocation intermediate containing elongation factor EFG/GDP/fusidic acid, mRNA, and tRNAs trapped in the AP/AP pe/E chimeric hybrid state.
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Zhou, J, Lancaster, L, Donohue, J.P, Noller, H.F.
登録日2014-07-02
公開日2014-10-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.8 Å)
主引用文献How the ribosome hands the A-site tRNA to the P site during EF-G-catalyzed translocation.
Science, 345, 2014
4W2E
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Crystal structure of Elongation Factor 4 (EF4/LepA) bound to the Thermus thermophilus 70S ribosome
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Gagnon, M.G, Lin, J, Steitz, T.A.
登録日2014-06-04
公開日2014-10-01
最終更新日2023-07-26
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of elongation factor 4 bound to a clockwise ratcheted ribosome.
Science, 345, 2014
4W2F
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BU of 4w2f by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with amicoumacin, mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4W2G
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BU of 4w2g by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (soaked), mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4W2H
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BU of 4w2h by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with pactamycin (co-crystallized), mRNA and deacylated tRNA in the P site
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Osterman, I.A, Szal, T, Tashlitsky, V.N, Serebryakova, M.V, Kusochek, P, Bulkley, D, Malanicheva, I.A, Efimenko, T.A, Efremenkova, O.V, Konevega, A.L, Shaw, K.J, Bogdanov, A.A, Rodnina, M.V, Dontsova, O.A, Mankin, A.S, Steitz, T.A, Sergiev, P.V.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Amicoumacin a inhibits translation by stabilizing mRNA interaction with the ribosome.
Mol.Cell, 56, 2014
4W2I
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Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S Ribosomal Protein S10, ...
著者Polikanov, Y.S, Szal, T, Jiang, F, Gupta, P, Matsuda, R, Shiozuka, M, Steitz, T.A, Vazquez-Laslop, N, Mankin, A.S.
登録日2014-09-12
公開日2014-10-15
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA.
Mol.Cell, 56, 2014
4W4G
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BU of 4w4g by Molmil
Postcleavage state of 70S bound to HigB toxin and AAA (lysine) codon
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Schureck, M.A, Maehigashi, T, Dunkle, J.A, Dunham, C.M.
登録日2014-08-14
公開日2015-10-21
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Defining the mRNA recognition signature of a bacterial toxin protein.
Proc.Natl.Acad.Sci.USA, 112, 2015
4WF1
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BU of 4wf1 by Molmil
Crystal structure of the E. coli ribosome bound to negamycin.
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ...
著者Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C.
登録日2014-09-11
公開日2014-11-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome.
Proc.Natl.Acad.Sci.USA, 111, 2014
4WOI
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BU of 4woi by Molmil
4,5-linked aminoglycoside antibiotics regulate the bacterial ribosome by targeting dynamic conformational processes within intersubunit bridge B2
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Pulk, A, Cate, J.H.D, Blanchard, S, Wasserman, M, Altman, R, Zhou, Z, Zinder, J, Green, K, Garneau-Tsodikova, S.
登録日2014-10-15
公開日2015-08-05
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Chemically related 4,5-linked aminoglycoside antibiotics drive subunit rotation in opposite directions.
Nat Commun, 6, 2015
4WPO
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BU of 4wpo by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the pre-translocational state
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-20
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4WQ1
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Complex of 70S ribosome with tRNA-Tyr and mRNA with C-A mismatch in the first position in the A-site.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-21
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WQF
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BU of 4wqf by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G and fusidic acid in the post-translocational state
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-21
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4WQR
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BU of 4wqr by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the first position in the A-site.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-22
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.15 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WQU
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BU of 4wqu by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G trapped by the antibiotic dityromycin
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-22
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4WQY
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BU of 4wqy by Molmil
Crystal structure of the Thermus thermophilus 70S ribosome in complex with elongation factor G in the post-translocational state (without fusitic acid)
分子名称: 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ...
著者Lin, J, Gagnon, M.G, Steitz, T.A.
登録日2014-10-22
公開日2015-01-28
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Conformational Changes of Elongation Factor G on the Ribosome during tRNA Translocation.
Cell, 160, 2015
4WR6
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BU of 4wr6 by Molmil
Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-23
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WRA
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BU of 4wra by Molmil
Complex of 70S ribosome with tRNA-Tyr and mRNA with A-A mismatch in the first position in the A-site and with antibiotic paromomycin.
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-23
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015
4WRO
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BU of 4wro by Molmil
Complex of 70S ribosome with tRNA-Phe and mRNA with C-A mismatch in the second position in the A-site
分子名称: 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ...
著者Rozov, A, Demeshkina, N, Yusupov, M, Yusupova, G.
登録日2014-10-24
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.05 Å)
主引用文献Structural insights into the translational infidelity mechanism.
Nat Commun, 6, 2015

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