5FQB
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![BU of 5fqb by Molmil](/molmil-images/mine/5fqb) | Crystal Structure of Bacillus cereus Metallo-Beta-Lactamase with 2C | 分子名称: | (4~{R})-4-[[4-(aminomethyl)phenyl]carbonylamino]-3,3-bis(oxidanyl)-2-oxa-3-boranuidabicyclo[4.4.0]deca-1(10),6,8-triene-10-carboxylic acid, BETA-LACTAMASE 2, GLYCEROL, ... | 著者 | Cahill, S.T, Brem, J, McDonough, M.A, Schofield, C.J. | 登録日 | 2015-12-08 | 公開日 | 2016-08-10 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.899 Å) | 主引用文献 | Structural basis of metallo-beta-lactamase, serine-beta-lactamase and penicillin-binding protein inhibition by cyclic boronates. Nat Commun, 7, 2016
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5HH5
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![BU of 5hh5 by Molmil](/molmil-images/mine/5hh5) | |
2FHX
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![BU of 2fhx by Molmil](/molmil-images/mine/2fhx) | Pseudomonas aeruginosa SPM-1 metallo-beta-lactamase | 分子名称: | 1,2-ETHANEDIOL, AZIDE ION, CHLORIDE ION, ... | 著者 | Murphy, T.A, Catto, L.E, Halford, S.E, Hadfield, A.T, Minor, W, Walsh, T.R, Spencer, J. | 登録日 | 2005-12-27 | 公開日 | 2006-01-17 | 最終更新日 | 2022-04-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Crystal Structure of Pseudomonas aeruginosa SPM-1 Provides Insights into Variable Zinc Affinity of Metallo-beta-lactamases. J.Mol.Biol., 357, 2006
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5HIQ
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![BU of 5hiq by Molmil](/molmil-images/mine/5hiq) | |
2H6A
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![BU of 2h6a by Molmil](/molmil-images/mine/2h6a) | Crystal structure of the zinc-beta-lactamase L1 from Stenotrophomonas maltophilia (mono zinc form) | 分子名称: | Metallo-beta-lactamase L1, SULFATE ION, ZINC ION | 著者 | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | 登録日 | 2006-05-31 | 公開日 | 2007-04-17 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
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2GMN
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![BU of 2gmn by Molmil](/molmil-images/mine/2gmn) | Crystal structure of BJP-1, a subclass B3 metallo-beta-lactamase of Bradyrhizobium japonicum | 分子名称: | Metallo-beta-lactamase, ZINC ION | 著者 | Calderone, V, Benvenuti, M, Stoczko, M, Docquier, J.D, Rossolini, G.M, Mangani, S. | 登録日 | 2006-04-07 | 公開日 | 2007-04-24 | 最終更新日 | 2017-10-18 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Postgenomic scan of metallo-beta-lactamase homologues in rhizobacteria: identification and characterization of BJP-1, a subclass B3 ortholog from Bradyrhizobium japonicum. Antimicrob.Agents Chemother., 50, 2006
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2GKL
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![BU of 2gkl by Molmil](/molmil-images/mine/2gkl) | Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate | 分子名称: | Beta-lactamase, GLYCEROL, PYRIDINE-2,4-DICARBOXYLIC ACID, ... | 著者 | Garau, G, Dideberg, O. | 登録日 | 2006-04-03 | 公開日 | 2007-03-13 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.86 Å) | 主引用文献 | Competitive Inhibitors of the CphA Metallo-{beta}-Lactamase from Aeromonas hydrophila Antimicrob.Agents Chemother., 51, 2007
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5HIS
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2GFK
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![BU of 2gfk by Molmil](/molmil-images/mine/2gfk) | Crystal structure of the zinc-beta-lactamase l1 from stenotrophomonas maltophilia (inhibitor 2) | 分子名称: | 2,5-DIPHENYLFURAN-3,4-DICARBOXYLIC ACID, DI(HYDROXYETHYL)ETHER, Metallo-beta-lactamase L1, ... | 著者 | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | 登録日 | 2006-03-22 | 公開日 | 2007-03-27 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
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5IQK
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![BU of 5iqk by Molmil](/molmil-images/mine/5iqk) | Rm3 metallo-beta-lactamase | 分子名称: | ZINC ION, beta-lactamase Rm3 | 著者 | Salimraj, R, Spencer, J. | 登録日 | 2016-03-10 | 公開日 | 2016-03-23 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural and Biochemical Characterization of Rm3, a Subclass B3 Metallo-beta-Lactamase Identified from a Functional Metagenomic Study. Antimicrob.Agents Chemother., 60, 2016
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2HB9
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![BU of 2hb9 by Molmil](/molmil-images/mine/2hb9) | Crystal Structure of the Zinc-Beta-Lactamase L1 from Stenotrophomonas Maltophilia (Inhibitor 3) | 分子名称: | 4-AMINO-5-(2-METHYLPHENYL)-2,4-DIHYDRO-3H-1,2,4-TRIAZOLE-3-THIONE, Metallo-beta-lactamase L1, SULFATE ION, ... | 著者 | Nauton, L, Garau, G, Kahn, R, Dideberg, O. | 登録日 | 2006-06-14 | 公開日 | 2007-05-29 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | 主引用文献 | Structural insights into the design of inhibitors for the L1 metallo-beta-lactamase from Stenotrophomonas maltophilia. J.Mol.Biol., 375, 2008
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2DOO
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![BU of 2doo by Molmil](/molmil-images/mine/2doo) | The structure of IMP-1 complexed with the detecting reagent (DansylC4SH) by a fluorescent probe | 分子名称: | BETA-LACTAMASE IMP-1, N-[4-({[5-(DIMETHYLAMINO)-1-NAPHTHYL]SULFONYL}AMINO)BUTYL]-3-SULFANYLPROPANAMIDE, ZINC ION | 著者 | Kurosaki, H, Yamaguchi, Y, Yasuzawa, H, Jin, W, Yamagata, Y, Arakawa, Y. | 登録日 | 2006-05-01 | 公開日 | 2006-11-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Probing, inhibition, and crystallographic characterization of metallo-beta-lactamase (IMP-1) with fluorescent agents containing dansyl and thiol groups Chemmedchem, 1, 2006
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8HXP
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![BU of 8hxp by Molmil](/molmil-images/mine/8hxp) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-(but-3-en-1-yl)thiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-but-3-enyl-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HXO
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![BU of 8hxo by Molmil](/molmil-images/mine/8hxo) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-isobutylthiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-(2-methylpropyl)-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, GLYCEROL, ... | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.902 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HXE
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![BU of 8hxe by Molmil](/molmil-images/mine/8hxe) | Crystal structure of B3 L1 MBL in complex with 2-amino-5-(4-propylbenzyl)thiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-[(4-propylphenyl)methyl]-1,3-thiazole-4-carboxylic acid, Metallo-beta-lactamase L1 type 3, THIOCYANATE ION, ... | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-04 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HXU
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![BU of 8hxu by Molmil](/molmil-images/mine/8hxu) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-pentylthiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-pentyl-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ... | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.945 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HY2
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![BU of 8hy2 by Molmil](/molmil-images/mine/8hy2) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-phenethylthiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-(2-phenylethyl)-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ... | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HXN
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![BU of 8hxn by Molmil](/molmil-images/mine/8hxn) | Crystal structure of B2 Sfh-I MBL in complex with 2-amino-5-(4-(but-3-en-1-yloxy)benzyl)thiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-[(4-but-3-enoxyphenyl)methyl]-1,3-thiazole-4-carboxylic acid, Beta-lactamase, ETHANOL, ... | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HXW
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![BU of 8hxw by Molmil](/molmil-images/mine/8hxw) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-heptylthiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-heptyl-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, FORMIC ACID, ... | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.39 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HY6
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![BU of 8hy6 by Molmil](/molmil-images/mine/8hy6) | Crystal structure of B1 NDM-1 MBL in complex with 2-amino-5-phenethylthiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-(2-phenylethyl)-1,3-thiazole-4-carboxylic acid, GLYCEROL, Metallo-beta-lactamase type 2, ... | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HXI
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![BU of 8hxi by Molmil](/molmil-images/mine/8hxi) | Crystal structure of B3 L1 MBL in complex with 2-amino-5-(4-isopropylbenzyl)thiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-[(4-propan-2-ylphenyl)methyl]-1,3-thiazole-4-carboxylic acid, GLYCEROL, Metallo-beta-lactamase L1 type 3, ... | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-04 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.81 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HY1
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![BU of 8hy1 by Molmil](/molmil-images/mine/8hy1) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-(thiophen-2-ylmethyl)thiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-(thiophen-2-ylmethyl)-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.937 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HX5
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![BU of 8hx5 by Molmil](/molmil-images/mine/8hx5) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-(4-methoxybenzyl)thiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-[(4-methoxyphenyl)methyl]-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-04 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HXV
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![BU of 8hxv by Molmil](/molmil-images/mine/8hxv) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-hexylthiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-hexyl-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-05 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.603 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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8HYD
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![BU of 8hyd by Molmil](/molmil-images/mine/8hyd) | Crystal structure of B1 VIM-2 MBL in complex with 2-amino-5-(2-(thiophen-2-yl)ethyl)thiazole-4-carboxylic acid | 分子名称: | 2-azanyl-5-(2-thiophen-2-ylethyl)-1,3-thiazole-4-carboxylic acid, Beta-lactamase class B VIM-2, ZINC ION | 著者 | Yan, Y.-H, Zhu, K.-R, Li, G.-B. | 登録日 | 2023-01-06 | 公開日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | 主引用文献 | Discovery of 2-Aminothiazole-4-carboxylic Acids as Broad-Spectrum Metallo-beta-lactamase Inhibitors by Mimicking Carbapenem Hydrolysate Binding. J.Med.Chem., 66, 2023
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