2GKL
Crystal structure of the zinc carbapenemase CPHA in complex with the inhibitor pyridine-2,4-dicarboxylate
Summary for 2GKL
Entry DOI | 10.2210/pdb2gkl/pdb |
Related | 1X8G 1X8H 1X8I |
Descriptor | Beta-lactamase, ZINC ION, PYRIDINE-2,4-DICARBOXYLIC ACID, ... (5 entities in total) |
Functional Keywords | hydrolase, lactamase, inhibitor, zn |
Biological source | Aeromonas hydrophila |
Cellular location | Periplasm (Probable): P26918 |
Total number of polymer chains | 1 |
Total formula weight | 25729.63 |
Authors | Garau, G.,Dideberg, O. (deposition date: 2006-04-03, release date: 2007-03-13, Last modification date: 2023-10-25) |
Primary citation | Horsfall, L.E.,Garau, G.,Lienard, B.M.R.,Dideberg, O.,Schofield, C.J.,Frere, J.M.,Galleni, M. Competitive Inhibitors of the CphA Metallo-{beta}-Lactamase from Aeromonas hydrophila Antimicrob.Agents Chemother., 51:2136-2142, 2007 Cited by PubMed: 17307979DOI: 10.1128/AAC.00866-06 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.86 Å) |
Structure validation
Download full validation report