5FQB

Crystal Structure of Bacillus cereus Metallo-Beta-Lactamase with 2C

Summary for 5FQB

Entry DOI	10.2210/pdb5fqb/pdb
Related	5FQA
Descriptor	BETA-LACTAMASE 2, ZINC ION, (4~{R})-4-[[4-(aminomethyl)phenyl]carbonylamino]-3,3-bis(oxidanyl)-2-oxa-3-boranuidabicyclo[4.4.0]deca-1(10),6,8-triene-10-carboxylic acid, ... (6 entities in total)
Functional Keywords	hydrolase, antibiotic resistance, lactamase
Biological source	BACILLUS CEREUS
Total number of polymer chains	1
Total formula weight	25671.65
Authors	Cahill, S.T.,Brem, J.,McDonough, M.A.,Schofield, C.J. (deposition date: 2015-12-08, release date: 2016-08-10, Last modification date: 2024-01-10)
Primary citation	Brem, J.,Cain, R.,Cahill, S.,McDonough, M.A.,Clifton, I.J.,Jimenez-Castellanos, J.C.,Avison, M.B.,Spencer, J.,Fishwick, C.W.,Schofield, C.J. Structural basis of metallo-beta-lactamase, serine-beta-lactamase and penicillin-binding protein inhibition by cyclic boronates. Nat Commun, 7:12406-12406, 2016 Cited by PubMed: 27499424 DOI: 10.1038/ncomms12406 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.899 Å)

Structure validation