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8X19
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BU of 8x19 by Molmil
Structure of nucleosome-bound SRCAP-C in the ADP-BeFx-bound state
分子名称: ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Actin, ...
著者Yu, J, Wang, Q, Yu, Z, Li, W, Wang, L, Xu, Y.
登録日2023-11-06
公開日2024-03-06
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural insights into histone exchange by human SRCAP complex.
Cell Discov, 10, 2024
4EXT
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BU of 4ext by Molmil
Structure of polymerase-interacting domain of human Rev1 in complex with translesional synthesis polymerase zeta
分子名称: DNA repair protein REV1, Mitotic spindle assembly checkpoint protein MAD2B, peptide from DNA polymerase zeta catalytic subunit
著者Liu, D.N, Ryu, K.S, Ko, J.S, Choi, B.S.
登録日2012-05-01
公開日2013-05-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Insights into the scaffold mechanism of human Rev1 in translesional synthesis revealed by structural studies on its polymerase-interacting domain
To be Published
5WXN
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BU of 5wxn by Molmil
Structure of the LKB1 and 14-3-3 complex
分子名称: 14-3-3 protein zeta/delta, Serine/threonine-protein kinase STK11
著者Ding, S, Shi, Z.B.
登録日2017-01-08
公開日2017-04-19
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.93 Å)
主引用文献Structure of the complex of phosphorylated liver kinase B1 and 14-3-3 zeta
Acta Crystallogr F Struct Biol Commun, 73, 2017
2R1V
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BU of 2r1v by Molmil
Norepinephrine quinone conjugation to DJ-1
分子名称: DJ-1
著者Zhongtao, Z, Yue, F.
登録日2007-08-23
公開日2008-08-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献DJ-1 activation by catechol quinone conjugation
To be Published
2QAG
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BU of 2qag by Molmil
Crystal structure of human septin trimer 2/6/7
分子名称: GUANOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, Septin-2, ...
著者Sirajuddin, M.
登録日2007-06-15
公開日2007-08-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (4 Å)
主引用文献Structural insight into filament formation by mammalian septins.
Nature, 449, 2007
2R1T
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BU of 2r1t by Molmil
dopamine quinone conjugation to DJ-1
分子名称: DJ-1
著者Zhongtao, Z, Yue, F.
登録日2007-08-23
公開日2008-08-26
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献DJ-1 is a proisopeptidase
To be Published
5XF3
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BU of 5xf3 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,R-configuration)
分子名称: (1R,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
4F6N
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BU of 4f6n by Molmil
Crystal structure of Kaiso zinc finger DNA binding protein in complex with methylated CpG site DNA
分子名称: DNA (5'-D(*CP*GP*TP*AP*TP*AP*GP*AP*(5CM)P*GP*(5CM)P*GP*GP*TP*GP*AP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*TP*CP*AP*CP*(5CM)P*GP*(5CM)P*GP*TP*CP*TP*AP*TP*AP*CP*G)-3'), GLYCEROL, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
4F6M
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BU of 4f6m by Molmil
Crystal structure of Kaiso zinc finger DNA binding domain in complex with Kaiso binding site DNA
分子名称: DNA (5'-D(*CP*GP*TP*TP*AP*TP*TP*GP*GP*CP*AP*GP*GP*AP*AP*GP*CP*AP*C)-3'), DNA (5'-D(*GP*TP*GP*CP*TP*TP*CP*CP*TP*GP*CP*CP*AP*AP*TP*AP*AP*CP*G)-3'), Transcriptional regulator Kaiso, ...
著者Buck-Koehntop, B.A, Stanfield, R.L, Ekiert, D.C, Martinez-Yamout, M.A, Dyson, H.J, Wilson, I.A, Wright, P.E.
登録日2012-05-15
公開日2012-09-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Molecular basis for recognition of methylated and specific DNA sequences by the zinc finger protein Kaiso.
Proc.Natl.Acad.Sci.USA, 109, 2012
5XF5
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BU of 5xf5 by Molmil
Nucleosome core particle with an adduct of a binuclear RAPTA (Ru-arene-phosphaadamantane) compound having a 1,2-diphenylethylenediamine linker (R,S-configuration)
分子名称: (1S,2R)-1,2-diphenylethane-1,2-diamine, DNA (145-MER), Histone H2A type 1-B/E, ...
著者Ma, Z, Adhireksan, Z, Murray, B.S, Dyson, P.J, Davey, C.A.
登録日2017-04-07
公開日2017-10-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.82 Å)
主引用文献Nucleosome acidic patch-targeting binuclear ruthenium compounds induce aberrant chromatin condensation
Nat Commun, 8, 2017
4FR3
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BU of 4fr3 by Molmil
Crystal structure of human 14-3-3 sigma in complex with TASK-3 peptide and stabilizer 16-O-Me-FC-H
分子名称: (4R,5R,6R,6aS,9S,9aE,10aR)-5-hydroxy-9-(methoxymethyl)-6,10a-dimethyl-3-(propan-2-yl)-1,2,4,5,6,6a,7,8,9,10a-decahydrodicyclopenta[a,d][8]annulen-4-yl alpha-D-glucopyranoside, 14-3-3 protein sigma, MAGNESIUM ION, ...
著者Ottmann, C, Anders, C, Schumacher, B.
登録日2012-06-26
公開日2013-05-08
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A semisynthetic fusicoccane stabilizes a protein-protein interaction and enhances the expression of k(+) channels at the cell surface.
Chem.Biol., 20, 2013
5XFL
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BU of 5xfl by Molmil
Crystal structure of the force-sensing device region of alpha N-catenin
分子名称: Catenin alpha-2
著者Hirano, Y, Hakoshima, T.
登録日2017-04-10
公開日2018-03-28
最終更新日2024-03-27
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The force-sensing device region of alpha-catenin is an intrinsically disordered segment in the absence of intramolecular stabilization of the autoinhibitory form
Genes Cells, 23, 2018
2R8U
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BU of 2r8u by Molmil
Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution
分子名称: MOLYBDATE ION, Microtubule-associated protein RP/EB family member 1
著者Huang, X, Lovelace, L.L, Smith, D, Lebioda, L.
登録日2007-09-11
公開日2008-09-23
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Structure of fragment of human end-binding protein 1 (EB1) containing the N-terminal domain at 1.35 A resolution
To be Published
4FJ3
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BU of 4fj3 by Molmil
14-3-3 isoform zeta in complex with a diphoyphorylated C-RAF peptide
分子名称: 14-3-3 protein zeta/delta, RAF proto-oncogene serine/threonine-protein kinase
著者Ottmann, C, Molzan, M.
登録日2012-06-11
公開日2012-09-05
最終更新日2013-07-10
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Synergistic binding of the phosphorylated S233- and S259-binding sites of C-RAF to one 14-3-3zeta dimer
J.Mol.Biol., 423, 2012
8Y0X
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BU of 8y0x by Molmil
Dormant ribosome with SERBP1
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Du, M, Zeng, F.
登録日2024-01-23
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献The global structure of dormant ribosome
To Be Published
8XBW
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BU of 8xbw by Molmil
The cryo-EM structure of the RAD51 N-terminal lobe domain bound to the histone H4 tail of the nucleosome
分子名称: DNA (5'-D(P*AP*CP*CP*GP*CP*TP*TP*AP*AP*AP*CP*GP*CP*AP*CP*GP*TP*A)-3'), DNA (5'-D(P*TP*AP*CP*GP*TP*GP*CP*GP*TP*TP*TP*AP*AP*GP*CP*GP*GP*T)-3'), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-12-07
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (2.89 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
8YTI
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BU of 8yti by Molmil
Crystal Structure of Nucleosome-H1x Linker Histone Assembly (sticky-169a DNA fragment)
分子名称: CALCIUM ION, CHLORIDE ION, DNA (169-MER), ...
著者Adhireksan, Z, Qiuye, B, Padavattan, S, Davey, C.A.
登録日2024-03-26
公開日2024-04-03
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Linker Histones Associate Heterogeneously with Nucleosomes in the Condensed State
To Be Published
6DCX
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BU of 6dcx by Molmil
iASPP-PP-1c structure and targeting of p53
分子名称: RelA-associated inhibitor, Serine/threonine-protein phosphatase PP1-alpha catalytic subunit
著者Glover, J.N.M, Zhou, Y, Edwards, R.A.
登録日2018-05-08
公開日2019-05-15
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.408 Å)
主引用文献Flexible Tethering of ASPP Proteins Facilitates PP-1c Catalysis.
Structure, 27, 2019
8XBT
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BU of 8xbt by Molmil
The cryo-EM structure of the octameric RAD51 ring bound to the nucleosome with the linker DNA binding
分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-12-07
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.12 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
4N7G
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BU of 4n7g by Molmil
Crystal structure of 14-3-3zeta in complex with a peptide derived from ExoS
分子名称: 14-3-3 protein zeta/delta, Exoenzyme S, HEXAETHYLENE GLYCOL
著者Bier, D, Glas, A, Hahne, G, Grossmann, T, Ottmann, C.
登録日2013-10-15
公開日2014-02-19
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Constrained peptides with target-adapted cross-links as inhibitors of a pathogenic protein-protein interaction.
Angew.Chem.Int.Ed.Engl., 53, 2014
8XBU
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BU of 8xbu by Molmil
The cryo-EM structure of the decameric RAD51 ring bound to the nucleosome with the linker DNA binding
分子名称: DNA (153-MER), DNA (156-MER), DNA repair protein RAD51 homolog 1, ...
著者Shioi, T, Hatazawa, S, Ogasawara, M, Takizawa, Y, Kurumizaka, H.
登録日2023-12-07
公開日2024-03-27
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.24 Å)
主引用文献Cryo-EM structures of RAD51 assembled on nucleosomes containing a DSB site.
Nature, 628, 2024
7O07
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BU of 7o07 by Molmil
14-3-3sigma covalently bound to peptide (chloroacetamide-Cys interaction)
分子名称: 14-3-3 protein sigma, MAGNESIUM ION, Transcriptional coactivator YAP1
著者Somsen, B.A, Ottmann, C.
登録日2021-03-25
公開日2021-10-13
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.2 Å)
主引用文献Covalent flexible peptide docking in Rosetta.
Chem Sci, 12, 2021
8Y0W
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BU of 8y0w by Molmil
dormant ribosome with eIF5A, eEF2 and SERBP1
分子名称: 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ...
著者Du, M, Zeng, F.
登録日2024-01-23
公開日2024-02-07
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献dormant ribosome with eIF5A, eEF2 and SERBP1
To Be Published
4MTC
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BU of 4mtc by Molmil
Crystal structure of human C53A DJ-1
分子名称: 1,2-ETHANEDIOL, Protein DJ-1
著者Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L.
登録日2013-09-19
公開日2014-03-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.47 Å)
主引用文献DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.
J.Biol.Chem., 289, 2014
4N12
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BU of 4n12 by Molmil
Crystal structure of human E18D DJ-1 in complex with Cu
分子名称: 1,2-ETHANEDIOL, COPPER (II) ION, Protein DJ-1
著者Cendron, L, Girotto, S, Bisaglia, M, Tessari, I, Mammi, S, Zanotti, G, Bubacco, L.
登録日2013-10-03
公開日2014-03-05
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.478 Å)
主引用文献DJ-1 Is a Copper Chaperone Acting on SOD1 Activation.
J.Biol.Chem., 289, 2014

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